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Molecular biology fills gaps in knowledge of bat evolution

...hey diversified and how different bat families are related to each other," Springer said. "It also quantifies the fraction of the fossil record that is missing for bats." The team, using DNA sequencing, analyzed data from portions of 17 nuclear genes from representatives of all bat families. Their results ...

Lack of enzyme turns fat cells into fat burners

...ey enzyme inthe regulation of weight, obesity, and related problems."Wakil and his colleagues studied the oxidation of fatty acid andglucose in cultures of fat cells isolated from both normal and mutantmice that lacked ACC2. When the mice were fed a normal diet, fatty acidoxidation was 80 percent higher in t...

Current human embryonic stem cell lines contaminated UCSD/Salk team finds

...human cells aregenetically unable to make it. In a related paper published November29, 2004 by the Journal of...n of New York.In addition to Varki, authors of the related study in JBC includedMuriel Bardor, Ph.D. and Dzung Nguyen, Ph.D., post-doctoral fellows,and Sandra ...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...Laboratory of Molecular Medicine, used the closely related simian immunodeficiency virus (SIV) as a stand-in for HIV. By aiming an X-ray beam through a crystallized form of gp120, they obtained the first high-resolution three-dimensional images of the protein in its unbound form. They surmounted considerable...

UW's Rosetta software to unlock secrets of many human proteins

...eloped the program, "And how they arestructured is related to their function in the body."Because there is an astronomical number of possible conformations for agiven protein, collecting the data would take many thousands oflifetimes to complete with conventional computers, said Dr. RichardBonneau, one of th...

Researchers find how protein allows insects to detect and respond to pheromones

...eloped the program, "And how they arestructured is related to their function in the body."Because there is an astronomical number of possible conformations for agiven protein, collecting the data would take many thousands oflifetimes to complete with conventional computers, said Dr. RichardBonneau, one of th...

Male circumcision reduces risk of HIV transmission from women to men

...ristics, thedifference in probability of infection related to circumcision statusdid not change.In addition to the results on circumcision, another significant resultof the study was the high overall rate of per-contact infection. Inpast studies that attempted to calculate the probability offemale-to-male in...

A much-needed shot in the arm for HIV vaccine development

...healthresearch to address new health threats."In a related commentary on the plan, David D. Ho, Scientific Directorof the Aaron Diamond AIDS Research Center at the Rockefeller Universityin New York, said that "there is no doubt that this roadmap will beregarded as a useful instrument to bring greater cohesio...

New Technique for Tracking Gene Regulators

...ional genes, and help transfer thisinformation and related technology to the private sector for thebenefit of society (see DOEgenomes.org).Related Links * John Dunn's web site * Brookhaven Biology Department ...

Bacteria collection sheds light on urinary tract infections

... isolated from patients with UTIs were genetically related to E.coli strains from cows that were in the collection of strains at the Gastroenteric Disease Center. Riley and DebRoy reported their findings in a recent issue of Clinical Infectious Diseases. About 8 to 10 million people are diagnosed with urin...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

...asions I'veseen very promising drugs candidates or related research get cannedbecause no money was to be made...cals to attack knowntargets, and posting data from related chemistry and biologyexperiments. Volunteers could use chat rooms and bulletin boards toannounce dis...

Scientists seek answers on what activates deadly anthrax spores

...roup also would like to understand another closely related bacterium, Bacillus cereus, one strain of which can produce anthrax-like symptoms. The research team includes Conn Mallett, Ph.D., Derek Parsonage, Ph.D., graduate students Carleitta Paige, Jamie Wallen, and Tim Colussi, and senior research assistan...

Mitochondrial DNA mutations play significant role in prostate cancer

....To determine whether mtDNA mutations are causally related to prostatecancer, the researchers introduced into a prostate cancer cell linemtDNAs harboring a known disease-causing mtDNA mutation and, as acontrol, the same mtDNA but without the disease mutation. They theninjected these modified prostate cancer ...

Molecular machine may lead to new drugs to combat human diseases

...fe evolved. "It's thought that RNA, or a molecule related to RNA, possibly were the first biomolecules, because they are capable of both performing work and carrying around their own genetic code," Golden said. She and her research team used an intron from a bacteriophage, a molecule that attacks bacteria,...

Automatic extraction of gene/protein biological functions from biomedical text

...the demand for automatic extraction of information related to gene functions from text has been increasing. Results: We have developed a method for automatically extracting the biological process functions of genes/protein/families based on Gene Ontology (GO) from text using a shallow parser and sentence st...

Gene variations explain drug dose required to control seizures

... noting that many other anti-epilepsy drugs act on related brain proteins. "The range of doses taken by patients at epilepsy clinics is great," Goldstein said. "For someone at the higher end, it can take months to get their seizures under control. This study uncovers factors that might determine, in advance...

Scientists collaborate to assess health of global environment

...on desertification is due out in June; and reports related to wetlands, the role of the private sector and impacts on human health are scheduled for July. According to Mooney, these topics were chosen because the organizations that oversee major international treaties dealing with biological systems requeste...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...latively rare disease, it is but one of a group of related "lysosomal storage diseases," which in total occur in about one in 5,000 births. The current study is part of a large, collaborative effort at Duke University Medical Center to find an effective treatment for Pompe disease. The Duke team earlier dev...

Scientists decipher genome of fungus that can cause life-threatening infections

...ientists have deciphered thegenomes of two closely related strains of Cryptococcus neoformans, afungus whose ...thogenicity by comparing the genomes of twoclosely related strains of significantly different virulence. "Notonly have we established a genomic platform for t...

First 'atlas' of key brain genes could speed research on cancer, neurological diseases

...lities in thedevelopment or function of nerves and related structures.Although the gene regulators were pinpointed using mouse brains, themap applies to the human brain as well. “This is the first systematic mapping of all of the major brain areasthat shows what regulatory genes are expressed in those speci...

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Breaking Biology News(10 mins):NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3
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