Tag: "relapse" at biology news

Methamphetamine Abuse, HIV Infection Cause Changes in Brain Structure

...ties. These could potentially affect treatment and relapse prevention efforts, as well as things like money management and driving performance.?/p> The brain volume changes associated with methamphetamine abuse did not correlate with the amount of the drug a person ingested. However, the study results su...

Genes linked to treatment resistance in children with leukemia

...ype. No genotype was associated with hematological relapse among patients in the lower-risk arm of the study. The researchers also looked for evidence of leukemia in each patient's central nervous system (CNS), a region that is vulnerable to infiltration by cancer cells. Genetic variations may have particul...

'License to kill' enables powerful immune attack cells in mice

...creases the immune system's ability to fight off a relapse of the leukemia." ...

Many smokers fail to quit after cancer diagnosis

... of cancer patients who smoke continue to do so or relapse after trying to quit. The report, published in the January 1, 2006 issue of CANCER, a peer-reviewed journal of the American Cancer Society, says smoking cessation is an underutilized tool in cancer management and that healthcare providers often fai...

Microarray technology for tailoring breast cancer therapy

... 38 patients who had a poor prognosis - defined as relapse or death from any cause within 5 years. The remaining 121 patients were defined as the 'good prognosis' group. The researchers also used gene expression profiling to separate patients who did well with and without adjuvant therapy, and those whose tu...

Gene variation affects tamoxifen's benefit for breast cancer

... in the CYP2D6 gene appear to be at higher risk of relapse when treated with five years of tamoxifen." Researchers at the U-M Comprehensive Cancer Center were among the group to discover CYP2D6 metabolizes tamoxifen, and they are leading ongoing work looking at how genetic differences affect women's respons...

In SAD patients, autumn antidepressants can prevent winter depression

...s were then followed over the winter season. The relapse rate was 16% for patients taking bupropion extende...he spring, there was no increase in the depression relapse rate compared with the placebo group. Patients with SAD have episodes of depression occurring in th...

Gene expression profile helps predict chemotherapy response in ovarian cancer patients

... research is to help determine which patients will relapse and which will not, and to better understand the reasons for this." Cannistra's group has been working to develop a genetic profile of ovarian cancer that will enable clinicians to more accurately determine a patient's prognosis. As a first step in ...

St. Jude projects 90 percent cure rate for ALL

...y having the tools to precisely assess the risk of relapse in a specific patient, we can design the most effective treatments possible at the start of therapy. That's a key element of our success in raising the cure rate for ALL while limiting toxic effects of therapy." That success is based to a large exte...

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

...to administer, appears to be a better predictor of relapse and disease-free survival than the Gleason Score, ...Rodriguez said. "It is very difficult to predict relapse and cancer recurrence in men who have a score of 6 or 7," she said. "Half of patients with these sco...

AIDS-related cognitive impairment exists in two separate forms

...to administer, appears to be a better predictor of relapse and disease-free survival than the Gleason Score, ...Rodriguez said. "It is very difficult to predict relapse and cancer recurrence in men who have a score of 6 or 7," she said. "Half of patients with these sco...

Mayo Clinic study finds two genes predict outcome for breast cancer patients

...ion of women who are and are not at risk for early relapse or cancer-related death. Results of the study are...was previously discovered as a potential marker of relapse in hormone-receptor positive breast cancer treated with tamoxifen," says Matthew Goetz, M.D., who co...

Novel therapy combinations gain ground in treating hepatitis

... studies have shown that with 48 weeks of therapy, relapse rates are near 20 to 30 percent, but with an exten...2a) plus RBV for 72 weeks in patients with a prior relapse to 48 weeks of treatment. A total of 81 patients were treated with either CIFN or with pegIFN a2a f...

Successful lung cancer surgery not enough to break nicotine dependence in many smokers

... & Prevention, is the first to look at smoking relapse among people who were "forced" to quit due to impe...continue smoking despite the risk, but the rate of relapse ranged from a low of 13 percent to about 60 percent. This study was unique in that it sought to incl...

Gene expression test reveals ER and HER-2 status of breast tumors

...enomic test that could estimate the risk of cancer relapse after surgery, determine the ER and HER2 receptor status, and also gauge the sensitivity of the tumor to hormone therapy and chemotherapy," says Lajos Pusztai, M.D., Ph.D., associate professor in the M. D. Anderson Department of Breast Medical Oncolo...

New compound prevents alcoholic behavior, relapse in animals by blocking stress response

...ing factor (CRF), which is also thought to trigger relapse in rats that have developed a long-term dependency...th cases and eliminated the rats?susceptibility to relapse under stress. Yet the compound did not affect their native curiosity or lower levels of drinking alc...

Cancer stem cells similar to normal stem cells can thwart anti-cancer agents

... Donnenberg, the very fact that cancers can and do relapse after apparently successful therapy indicates the survival of a drug-resistant, tumor-initiating population of cells in many types of refractory cancers. “Because of the similarities between the way that normal stem cells and cancer stem cells protec...

Research shows cord blood comparable to matched bone marrow

...y when HLA types are mismatched. Rates of leukemia relapse also are lower with mismatched umbilical cord blood transplants. This study also showed that in addition to having a good match, higher cell doses for umbilical cord blood transplants improved survival rates. The study was done by extensive revie...

1