Clam embryo study shows pollutant mixture adversely affects nerve cell development
...own as BCE--can act synergistically to alter a key regulator in nervecell development. While scientists have previously studied the effectsof these pollutants individually, this is the first time anyone hasdemonstrated that BCE's components can work together to adverselyaffect neuron growth in a model organism...Novel Enzyme Shows Potential As An Anti-HIV Target
...or of transcription?, for example, is an essential regulator of HIV gene expression. Without Tat, HIV transcripts don’t reach full length and can’t effect viral replication. In a new study, Melanie Ott and colleagues identify an enzyme that regulates viral transcription by modifying Tat. The regulation of HIV...New Technique for Tracking Gene Regulators
...e they describe thehuman-genome binding sites of a regulator protein known as CREB.“Though scientists have now decoded almost all of the entire humangenome ?the series of nucleotide bases (labeled A, T, G, and C) thatmake up the source code for running the machinery of the cell ?we arejust beginning to deciphe...Fox Chase Cancer Center scientists identify immune-system mutation
...ll lineage. This indicates that Th-POK is a master regulator of the maturation process." Understanding the development of critical components of the immune system can contribute to medical advances in stimulating desirable immune responses and halting undesirable immune reactions, Kappes said. This understand......s regulatory structure, called chromatin, is a key regulator of gene expression in healthy and diseased cells, Bernstein said. Chromatin is composed of DNA spooled around bundles of histone proteins, and resembles a chain of beads which is then compressed into a working chromosome. Chemical tags placed on the ...