regulating 2 6

Tag: "regulating" at biology news

Pest control research leads to pain control discovery

...ces. "Our laboratory was initially interested in regulating the development of insect larvae," said Hammock, a distinguished professor of entomology and member of the National Academy of Sciences. The discovery switched the focus of the research from "pest control to pain control." M. Eric Gershwin, chief o...

Chewing up a key regulator of fat synthesis keeps mice lean despite a high-fat diet

...omeone weighing 200 pounds. Defining how molecules regulating fat storage interact could lead to novel measures to curb obesity. Further evidence linking TRB3 to disease comes from recent findings from a team of Italian scientists who report that mutations in the human TRB3 gene are associated with several ins...

Parkinson's disease mechanism discovered

...at one protein, called Ypt1p, which is involved in regulating trafficking could also be switched on to suppress alpha-synuclein toxicity in yeast cells. "Our findings indicated that this ER-to-Golgi trafficking pathway is intimately coupled to the pathology, although in humans there are likely others involved ...

The molecular mechanism of a diabetes vaccine revealed

...such precision, we can copy nature's own system in regulating the immune system and therefore, help to boost the immune system in preventing the destruction of insulin-producing pancreatic cells," says Cohen. Postdoctoral fellow Dr. Alexandra Zanin-Zhorov spearheaded the project; the other scientists participa...

Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent

...researchers induced theta in one of three ways ?by regulating the rats' anesthesia, by stimulating the septum directly with an injection of carbachol, or by using the sensory stimulation method of pinching the tail.) The amplitude and frequency of the theta rhythm of the epileptic rats was significantly alter...

Researchers identify human DNA on the fast track

...tend to be located near genes that are involved in regulating the function of genes. Furthermore, 12 of the regions are adjacent to genes involved in the development of the brain. The Nature paper looks in depth at the region that has undergone the most change in the human lineage, which the researchers calle...

Study links high levels of nitric oxide to infertility and sperm DNA damage

...ised as a molecule that plays an important role in regulating the biology and physiology of the reproductive system, and we know that it can affect human sperm functions, such as motility, viability and metabolism. At low concentrations it can have a positive effect on cells, but a negative effect at high conce...

Tropical forest CO2 emissions tied to nutrient increases

...ical rain forests play a dominant role on Earth in regulating atmospheric CO2, the primary greenhouse gas that has increased by roughly 33 percent since the Industrial Revolution began about 1760. A paper on the subject by Cleveland and CU-Boulder Associate Professor Alan Townsend of INSTAAR is being published...

Study identifies new role for breast cancer susceptibility gene

.... BRCA1 is known to serve as a tumor suppressor by regulating DNA damage repair and maintaining genomic stabilit...uppression beyond maintaining genomic stability by regulating intercellular signaling within the tissue microenvironment. This view will extend BRCA1's tumor supp...

New stem-cell findings can help the body to cure itself

...ature cells known as stem cells, but the mechanism regulating the number of new cells produced has remained something of a mystery. However, in a new study to be published by Cell stem-cell researcher Jonas Frisén has succeeded in showing how the body's own stem cells do just this. Working alongside an American...

Researchers find cause of frontotemporal dementia

...mong other things, the frontal lobe is involved in regulating behavior, movement and mood, and is responsible for cognitive functions like memory and speech. So, FTD is clinically characterized by changes in personality and, in a later stage, loss of cognitive functions. Looking for the needle in the haysta...

When it comes to gene transcription, random pauses aren’t quite so random, study finds

...ts into the control mechanisms that cells have for regulating the genes they express." ...

Brain region linked to fly slumber

...fore possible, the authors argue, that a mechanism regulating both sleep and learning could be evolutionarily conserved. So studying the mushroom bodies may help to throw light on the mechanisms governing vertebrate and invertebrate sleep. In addition to Allada, other authors on the Nature paper are Jena L. Pi...

Potato blight pathogenicity explained by genome plasticity

...large regulatory protein that exerts its effect by regulating the expression of other genes, possibly effector genes." While the exact mechanism by which these partial gene copies function as a source of modular diversity remains to be resolved, this study highlights the importance of genome plasticity in evol...

What controls stickiness of 'smart' chromosomal glue

...e cohesin-snipping enzyme separase plays a role in regulating step-wise cohesin loss; she and her colleagues are now exploring that possibility. ...

Salk scientists untangle steroid hormone signaling in plants

...the nucleus where it tweaked the activity of genes regulating plant growth. A closer inspection, however, revealed that BIN2 resides in multiple compartments of a cell, including the nucleus, and it is there--not in the cytoplasm--that BIN2 meets up with BES1 and prevents it from activating growth genes. "All...

Ozone recovering, but unlikely to stabilize at pre-1980 levels, says study

...the nucleus where it tweaked the activity of genes regulating plant growth. A closer inspection, however, revealed that BIN2 resides in multiple compartments of a cell, including the nucleus, and it is there--not in the cytoplasm--that BIN2 meets up with BES1 and prevents it from activating growth genes. "All...

New angiogenesis finding may help fight cancer growth

...gene for a compound that is supposedly involved in regulating the nervous system?" The researchers searched for NK-B receptors - molecules that can "recognize" and respond to NK-B - and found great numbers of them on endothelial cells, which line the inside of blood vessels. Endothelial cells form the inte...

Mobile DNA part of evolution's toolbox

...ems, as would be expected if the LF-SINE copy were regulating the activity of ISL1. The discoverer of mobile DNA elements, Barbara McClintock, suggested in 1950 that they might play a role in the regulation of genes -- a hypothesis that was more fully developed by Roy Britten and Eric Davidson in about 1970,...

New mechanism explains glucose effect on wakefulness

...inted how glucose inhibits neurons that are key to regulating wakefulness. In the process, they have discovered ...thus providing new insights into cellular pathways regulating vigilance states and energy balance," wrote Burdakov and colleagues. "These results provide evidenc...

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