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Tag: "regulating" at biology news

Bioartificial kidney under study at MCG

...ich are involved in diverse functions ranging from regulating vitamin D to modulating the immune response. "Existing forms of dialysis have only replaced the ability of the kidneys to rid the body of waste products and correct abnormalities in blood chemistry; they don't replace kidney function, " says Dr. Szer...

A new mechanism of regulating RNA degradation

...vestigators now know that it plays a major role in regulating the life span of numerous RNAs, and thus controls gene activity. To better understand what controls the NMD system, Maquat and her postdoctoral fellow, Yoon Ki Kim, Ph.D., used a critical component of the NMD complex, Upf1, as bait in a molecular fi...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...vestigators now know that it plays a major role in regulating the life span of numerous RNAs, and thus controls gene activity. To better understand what controls the NMD system, Maquat and her postdoctoral fellow, Yoon Ki Kim, Ph.D., used a critical component of the NMD complex, Upf1, as bait in a molecular fi...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

...ption factor, which also plays animportant role in regulating the interferon effect. Further functionalanalyses will be necessary to map the molecular mechanisms in detail.Besides the Rheumatology Clinic at Uppsala Akademiska Hospital,hospitals in Umeå and Lund, in Sweden, and several hospitals in Finlandas wel...

W.M. Keck Foundation funds study of friendly microbes

...wn chemical compounds that play important roles in regulating the properties of the microbial community and human physiology. To do so, the researchers will use a new type of mass spectrometer with an unprecedented capacity to accurately and rapidly identify these metabolites. "We very grateful to the Keck fou...

New Technique for Tracking Gene Regulators

...so scientists know itis important, particularly in regulating cell differentiation,survival, and the function of nerve cells. But there has been no easyway to screen the entire genome. “We are the first to do a genome-widesurvey,?says Dunn.The problem has been the sheer magnitude of information in the genome:th...

Novel Enzyme Shows Potential As An Anti-HIV Target

...ion was long thought to influence transcription by regulating the structure and function of chromatin, which is an assembly of proteins (mostly histones) and DNA. Another, more widely accepted model proposes that histone acetylation controls transcription by recruiting cofactors required for transcription. Ace...

Study finds more than one-third of human genome regulated by RNA

...he sidelines may be one of theprincipal players in regulating cellular mechanisms. "It's exciting to see how many genes are regulated by microRNAs. We nowknow that this type of gene control is much more widespread thanpreviously appreciated," says Whitehead Member and MIT professor ofbiology David Bartel.Micro...

NYU researchers simulate molecular biological clock

...he sidelines may be one of theprincipal players in regulating cellular mechanisms. "It's exciting to see how many genes are regulated by microRNAs. We nowknow that this type of gene control is much more widespread thanpreviously appreciated," says Whitehead Member and MIT professor ofbiology David Bartel.Micro...

An HIV Protein Plays a Surprising Role in Gene Activation

...oteins and mechanisms dedicated to the business of regulating gene expression, and retroviruses like HIV have evolved myriad ways of redirecting that machinery to their own benefit. Humans and other eukaryotes have three types of RNA polymerases, each charged with transcribing different types of genetic elemen...

Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers

..." Bradley said. "Their behavior indicates they are regulating oxygen." Bradley and Hetz will next work on developing a comprehensive model of insect breathing. "We'd like to expand our present model to explain all aspects of insect breathing. And we'd like to examine insects that do not show this pattern -- fo...

Zebrafish may hold key to understanding human nerve cell development

... glial cells play apreviously unidentified role in regulating the development of sensoryhair cell precursors -- the specialized neurons found in the inner earof humans that make hearing possible. This research increases ourunderstanding of how nerve cells develop and whether it may be possibleto regenerate thes...

Harmful Bacterium Commonly Found in Poultry May Survive Refrigeration and Frozen Storage Combined

... glial cells play apreviously unidentified role in regulating the development of sensoryhair cell precursors -- the specialized neurons found in the inner earof humans that make hearing possible. This research increases ourunderstanding of how nerve cells develop and whether it may be possibleto regenerate thes...

GenMAPP 2.0 released

... glial cells play apreviously unidentified role in regulating the development of sensoryhair cell precursors -- the specialized neurons found in the inner earof humans that make hearing possible. This research increases ourunderstanding of how nerve cells develop and whether it may be possibleto regenerate thes...

White blood cell waste disposal system plays critical regulatory role

...ep that is a key component of the feedback circuit regulating the balance between neutrophil production and destruction. The research, published in the March issue of Immunity, suggests that the process for disposal of dying neutrophils is actively linked to neutrophil production. A clear understanding of the p...

Scientists discover that host cell lipids facilitate bacterial movement

...t and modify the functions of proteins involved in regulating actin assembly. PIP2 and PIP3 also prevent capping proteins from binding to the ends of actin filaments, allowing new actin filament assembly. Because Listeria is capable of stimulating actin assembly and PIP2 and PIP3 are known to localize to regio...

Implanted Devices Detect High-Risk Heart Failure Patients

...able to appropriately react to external stimuli by regulating their beating action -- are known to be at higher risk of suffering a heart attack. The new insight from CRT-D devices is possible because they record detailed data on heart function 24 hours a day. These new findings are important for two reasons, ...

Chemists identify key gene in development of type 1 diabetes

...fighting diabetes, they say. "The MIF gene may be regulating other genes involved in type 1 diabetes," says Al-Abed. "We don't know yet, but we're looking into this." Besides drug intervention, the new finding could lead to gene therapy to prevent the disease, possibly by disrupting the network of genes involv...

Towards precise classification of cancers based on robust gene functional expression profiles

...fighting diabetes, they say. "The MIF gene may be regulating other genes involved in type 1 diabetes," says Al-Abed. "We don't know yet, but we're looking into this." Besides drug intervention, the new finding could lead to gene therapy to prevent the disease, possibly by disrupting the network of genes involv...

New component of the 'brakes' on nerve regeneration found

...perhaps beneficial to regeneration or recovery--in regulating response to injury. "Further characterization of the underlying mechanisms of these findings and their relation to myelin inhibition may provide important insights into designing therapeutic strategies to block myelin inhibition and cell death in the...

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