Anthrax paralyzes immune cells with lethal toxin, UF research shows
...lethal toxin blocks the function of a protein that regulates how actin assembles," said Southwick, who believes his findings may also explain how anthrax paralyzes other types of cells, like the platelets that normally help blood clot. "We know that patients with anthrax bleed," Southwick said, adding that ...Fat fish put obesity on the hook
... our brains called the “adipostat.” The adipostat regulates body weight homeostatically, like the thermostat in a house, and works to keep long-term energy stores—a.k.a. body fat—constant. The adipostat is what makes it difficult for people to lose weight and keep it off. “Americans—even children—are ge...Penn researchers link cell's protein recycling systems
...hers suggest that the level of the HDAC6 in a cell regulates its sensitivity to accumulation of misfolded proteins, and that increasing the activity of HDAC6 can prevent the degeneration normally associated with accumulating old, damaged proteins. The researchers suggest further that when proteasomes are impai...Brain holds clues to bipolar disorder
...– the complex machinery inside of nerve cells that regulates numerous processes inside the body. Using animal and cellular models, Dr. Manji and colleagues at NIMH showed that disruptions in these pathways resulted in many of the core symptoms of bipolar disorder and explained many other observations about the...Researchers discover inherited mutation for leukemia
...archers are now studying the chemical pathway that regulates the gene, considering possible therapies, working to identify other CLL families and looking for other predisposing genes. In 2005, other Ohio State Comprehensive Cancer Center researchers discovered a germline mutation in a gene for a microRNA t...FDA sees nanotech challenges in every product category it regulates
...al devices, and food products. Overall, the agency regulates products that are worth nearly $1.5 trillion annually and that account for almost 25 percent of US consumer spending. “Today, there are more than 500 manufacturer-identified nanotechnology consumer products being sold. These can be found in an onli...