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Tag: "regenerative" at biology news

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state

...ain their identity is key to the emerging field of regenerative medicine. “These findings may help us to understand how the key genes which control cell fate are regulated, and how, when dysregulated, they can lead to disease. This may ultimately allow us to develop targeted therapies to stimulate adult stem cell...

Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin

...embryonic stem cells, doctors practicing so-called regenerative medicine eventually might be able to extract stem cells from an individual’s blood, then grow them in the laboratory to large numbers and tweak them so that they are directed to create a needed organ. In this way, he said, physicians might avoid the ...

More recycling on the farm could reduce environmental problems

...'s reliance on oil imports and water. A switch to regenerative agriculture would involve a variety of changes, in...er. Yet despite similarities, Pearson's concept of regenerative agriculture is distinct from organic farming; for example, regenerative agriculture could use some c...

Master regulatory gene of epithelial stem cells identified

... p53 gene. Without p63, mutant mice run out of the regenerative epithelial stem cells. The findings also have imp...dies found that p63 maintains a steady pool of the regenerative cells, while other studies argued that p63 has more to do with causing the cells to differentiate in...

First demonstration of new hair follicle generation in an animal model

...rally believe that mammals had essentially no true regenerative qualities. (The liver can regenerate large portions, but it is not de novo regeneration; some of the original liver has to remain so that it can regenerate.) In this study, researchers found that wound healing in a mouse model created an “embryoni...

The sturdier sex? -- Study by Pittsburgh scientists finds female stem cells work better

...ology, is the first ever to report a difference in regenerative capabilities of muscle stem cells based on sex. ...sed on these results, future studies investigating regenerative medicine should consider the sex of the stem cells to be an important factor. Furthermore, investiga...

UW launches study testing adult stem cells for heart damage repair

...um medical intervention. This type of therapy - regenerative medicine - treats diseases by using growth factors...wth," explains Amish Raval, head of cardiovascular regenerative medicine at UW Health. The goal with this approach, he says, is to promote either angiogenesis, wh...

Selective marker found to indicate aggressive form of breast cancer

...ancer with similarities to mammary stem cells, the regenerative cells believed to be the site of breast cancer ini...helia." DiRenzo said. "If it is indeed specific to regenerative cells, then it will make for an excellent diagnostic tool for a cancer of regenerative mammary cells...

Stanford scientists make major breakthrough in regenerative medicine

... the first step toward a major revolution in human regenerative medicine—a future where advanced organ damage can ...a series of generations, suggesting that a similar regenerative process might be possible in people. "We hope the mechanisms underlying this phenomenon will ultim...

Research project tackles 'regeneration' gap

... pathways used by some of nature’s most remarkably regenerative animals. Already, UF McKnight Brain Institute ...is "bold" because it takes a comprehensive view of regenerative medicine, according to Arlene Y. Chiu, Ph.D., director for scientific activities at the California I...

Mechanical 'artificial hearts' can remove need for heart transplant by returning heart to normal

...ore therapeutic targets in this expanding field of regenerative therapy," he added. LVADs are currently mainly used in those patients awaiting heart transplant, whose heart failure is very severe. The researchers are hopeful that the technique used in this study could also be used to restore heart function amo...

How fish mend a broken heart

...e damaged cardiac muscle one of the most prominent regenerative failures of mammals," wrote Alexandra Lepilina and... certain amphibians and fish, display an "elevated regenerative spectrum, with many more tissues capable of impressive regeneration," they said. For instance, certa...

Cloned mice created from fully differentiated cells, a milestone in cloning research

...urrent studies may have important implications for regenerative medicine, since the findings suggest the potential of adult stem cells in this arena may be more limited than previously thought. However, of particular interest to Dr. Cheng is the relevance of their findings to cancer stem cell research. "An inte...

Key to zebrafish heart regeneration uncovered

...researchers find the key to unlocking this dormant regenerative capacity in mammals, and such an advance could lea...pecies. The key is to find a way to 'turn on' this regenerative ability." The research was supported by the National Institutes of Health, the American Heart Ass...

Stem cells engage in dialogue with the cells that regulate their futures

...hola-Baker added that stem cells hold high hope in regenerative medicine: tapping into the ways cells repair the body to create therapies to fix or replace injured tissues. She mentioned that it is thought that most, if not all, adult tissues contain stem cells. Through self-renewing division," she explained, ...

Diabetes slows nerve recovery after heart transplant

...lanted heart as a very specific model to study the regenerative capacity of the heart's sympathetic nervous system, we determined that reinnervation--or the heart's ability to develop new nerves to replace damaged ones--is slower in diabetic patients," said Frank M. Bengel, a visiting associate professor of radio...

Muscle and bone from an ink-jet printer

...nology could be the tailoring of tissue-engineered regenerative therapies. In preparation for preclinical studies, the Pittsburgh researchers are following up this work by combining the versatile ink-jet system with advanced live cell imaging developed at Carnegie Mellon’s Robotics Institute and Molecular Biosens...

Replacing insulin is top-ranked breakthrough foreseen for health in developing world

...ping countries seen emerging from the new world of regenerative medicine, according to a study published today in ...U of T Joint Centre for Bioethics), the study says regenerative medicine has the potential to help developing countries address a suite of disastrous health problem...

Neural stem cells lend the brain a surprising capacity for self-repair

...r restored the genes' activity and, with it, their regenerative potential. "At two weeks, the knockout animals' brains had developed a big hole," said Yuh-Nung Jan, a Howard Hughes Medical Institute investigator at the University of California, San Francisco. "We thought that the mice would not live long, but b...

Fish species plays surprise role in aiding coral reef recovery

...of species groups that underlie the resilience and regenerative capacity of coral reef ecosystems. ...

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(Date:7/11/2014)... 3, 2014, Shenzhen, China Researchers from Salk Institute ... the first time evaluated the safety and reliability ... successfully developed a new method, TALEN-HDAdV, which could ... stem cell (hiPSC). This study published online in ... theoretical foundation for stem cell-based gene therapy. , ...
(Date:7/11/2014)... 2014 The increased risk of kidney injury related ... fluids reflects the mass of HES molecules, according to ... journal of the International Anesthesia Research Society (IARS). , ... effect of HES on cultured human renal proximal tubule ... Wunder and colleagues of University Hospital Wrzburg, Austria. ...
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