Reducing antibiotic use lowers rates of drug-resistant bacteria
...seases, now available online. The study found that reducing antibiotic use for pediatric respiratory tract inf...f Institut Pasteur. Intervention methods such as reducing the number of prescriptions and, when ordered, the dose and duration of antibiotics, "can induce sig...Researchers identify molecular anchor that allows bacterial invasion of central nervous system
...cterial interactions with the blood-brain barrier, reducing mortality rates up to 90 percent in mice. "Mice that were infected with the normal, or wild-type, Streptococcus bacteria containing iagA died within days showing evidence of bacterial meningitis. In contrast, most of the mice survived when infecte...New technique multiplies life span in simple organisms
...ancer Center, Longo is studying the feasibility of reducing or preventing the age-dependent DNA mutations that cause cancer. Longo and his collaborators began studying SIR2 in 2000, soon after a well-known set of experiments by Leonard Guarente at the Massachusetts Institute of Technology. Guarente was the f...Bare metal stents deliver gene therapy to heart vessels with less inflammation in animal studies
...eneficial genes to patients with heart disease, by reducing the risk of inflammation that often negates initial benefits. The new technique, using a compound that binds in an extremely thin layer to bare metal surfaces, may have potential uses in other areas of medicine that make use of metallic implants. Ca...Evolutionary conservation of a mechanism of longevity from worms to mammals
...oncluding that "�the longevity-promoting effect of reducing clk-1/mclk1 activity that was initially observed in C. elegans is conserved in mice, supporting the idea that some molecular mechanisms of aging are shared throughout the animal kingdom." ...Molecular research suggest shift needed in how some drugs are created
...ich would be beneficial for treating arthritis and reducing inflammation, said Nair, who also is a researcher in the Center for Biophysics and Computational Biology at Illinois. Signaling in the pathway uses protein molecules that contain death-domains. "What our structure tells us is that the particular arr...Federal grant funds research on novel HIV therapy
...immune cells, improving innate immune function and reducing symptoms of depression that are associated with the disease. Steven D. Douglas, M.D., professor of Pediatrics, chief of the Section of Immunology and director of Clinical Immunology Laboratories at The Children's Hospital of Philadelphia, is the pri...Cord blood cells may widen treatment window for stroke
... greatly curbed the brain's inflammatory response, reducing the size of the stroke and resulting in greatly improved recovery. The rats' inflammatory response to injury from stroke peaked 48 hours after the brain attack, which was when intravenous delivery of the cells appeared most beneficial. "We were very...Johns Hopkins flu expert calls for mandatory vaccination of health care workers
...flu shots have been almost 88 percent effective at reducing the risk of flu infection and that they reduced by one-half the number of deaths among hospital patients from the disease. Perl's view, which is likely to inform further debate on the subject of voluntary versus mandatory worker vaccination programs...Research: Snails were overlooked contributors to marsh destruction
...ater-borne pollutants and calm storm-driven waves, reducing the threat of hurricane-induced flood and erosion. So scientists and citizens alike watched with alarm as the marshes started dying off from Louisiana to South Carolina beginning in 1999. Most earlier research pointed to the effects of a severe drou...In SAD patients, autumn antidepressants can prevent winter depression
...sant treatment in the fall offers a new option for reducing the rate of fall-winter depression in patients with SAD, the results suggest. "It is a highly novel approach to start treatment before the development of a major depressive disorder," says Dr. Rosenthal, author of the newly revised Winter Blues: Sea...Penn researchers study the use of ultrasound for treatment of cancer
...t on shutting down the blood flow to the tumor and reducing the growth of the tumor in mice," said Chandra Sehgal, PhD, Director of Ultrasound Research in the Department of Radiology at Penn and the study's principal investigator. "We wanted to study this use of ultrasound because we observed that some of th...Technique offers new view of dynamic biological landscape
...ediate during the conversion of a gene to protein, reducing its lifespan by mutating the mRNA message lowers the amount of protein the cell can produce. The group called this approach "decreased abundance by mRNA perturbation" (DAmP). "The DAmP technique gave us a way of lowering the abundance of a target g...UCR environmental scientists propose chemical solution to cleaning California's Salton Sea
...amide, a new type of polymer used increasingly for reducing sediment loss from agricultural fields. Results f...f fertilizers appear to be the best approaches for reducing algae blooms in the Salton Sea," Amrhein said. Unless measures are taken to clean the Salton Sea, e...Biologists discover new pathway into plant cells
... produce multiple toxins that attack wheat plants, reducing yields and ruining wheat used as seed. In the United States, it's a particular problem in the Great Plains and Midwest. Ciuffetti has spent much of her career studying these "host-selective" toxins. "Until now, we didn't really know exactly how the ...Study finds that nutritionally enhanced rice reduces iron deficiency
...her levels of iron can have an important impact on reducing micronutrient malnutrition, according to a new stu...on in the body and can significantly contribute to reducing micronutrient malnutrition. "In the past, we relied on supplements and fortification to overcome ...Birth defects: 8 million annually worldwide
...sparities between richer and poorer nations and at reducing the toll of infant deaths, especially in low- and middle-income countries. "Experience from high-income countries shows that overall mortality and disability from birth defects could be reduced by up to 70 percent if the recommendations in this rep...Embryos tell story of Earth's earliest animals
...educing" substance, such as hydrogen sulfide. Such reducing substances slow or stop the internal degradation p...rtilization envelope did not fossilize, even under reducing conditions. The scientists predict early animal fossils from 500 million years ago will be embryos...Infection 'alarm' yields clues to immune system behavior
...ght be helped by a drug that curbs inflammation by reducing the sensitivity of IKK. Still other diseases that are characterized by a weak inflammatory response might be helped by a drug that makes IKK even more sensitive to infection messages. The researchers believe their computer model of this cellular ala...... into a useful eco-friendly plastic, significantly reducing the environmental impact of this ubiquitous, but difficult-to-recycle waste stream, according to a study scheduled to appear in the April 1 issue of the American Chemical Society journal, Environmental Science & Technology . The microbes, a spe...