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Tag: "recurrence" at biology news

Major cancer study aims to identify protein markers for early-stage disease

...a cancer's response to treatment and to detect the recurrence of cancer after treatment. "This is an extraordinarily exciting endeavor," says Fisher. "We truly believe in this project, and that it is going to help people. We think that the methods we're proposing will work." The UCSF component of this res...

Report focuses on the role good microbes play in future medicine

...g the incidence of kidney stones, and reducing the recurrence of bladder tumors. ...

Pak1 expression increases tamoxifen resistance in breast cancer patients

...sociated with the women's chances of breast cancer recurrence and the effects of tamoxifen therapy. The authors...w levels of Pak1 had longer survival without tumor recurrence than patients who did not receive treatment. Overexpression of certain types of Pak1 was associated ...

First-ever genomic test predicts which lung cancer patients need chemotherapy to live

...mors that indicate a patient is likely to suffer a recurrence of disease. Recurrent tumors are typically fatal, ...ch early-stage lung cancer patients would suffer a recurrence of their cancer and which patients would not," said Anil Potti, M.D., an assistant professor of medi...

Combined treatment extends life expectancy for lung cancer patients

...world to administer this combined treatment. The recurrence rate was much lower with the combined treatment. W...average of 44 months. While there was an increased recurrence rate in larger tumors ?33 percent recurred at an average of 34 months ?the overall survival rate was...

Mass. General study finds potential ovarian cancer stem cells

...esponsible for the ultimately fatal drug-resistant recurrence that is characteristic of ovarian cancer," says Paul Szotek, MD, of the MGH Pediatric Surgical Research Laboratories, first author of the PNAS report. "We believe this likely is the first time stem-like cells have been found in models of ovarian can...

New genetic test for breast cancer

...Adding chemotherapy can further reduce the risk of recurrence by about 25 percent, but it benefits only a small ...s genetic assessment estimates a patient's risk of recurrence more precisely than standard clinical characteristics, such as tumor size and grade. It also helps ...

AIDS-related cognitive impairment exists in two separate forms

...It is very difficult to predict relapse and cancer recurrence in men who have a score of 6 or 7," she said. "Hal...cking the methylation of a single gene can predict recurrence of prostate cancer in patients who have had their glands surgically removed. In a clinical study of...

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

...It is very difficult to predict relapse and cancer recurrence in men who have a score of 6 or 7," she said. "Hal...cking the methylation of a single gene can predict recurrence of prostate cancer in patients who have had their glands surgically removed. In a clinical study of...

Faults in newly discovered breast stem cells may lead to tumours

... eliminated by chemotherapy sometimes experience a recurrence of their cancer. A cancerous stem cell could provide one possible explanation for such a recurrence. Chemotherapy works by targeting cells that are dividing rapidly, which is typical behaviour of cancer cells. But an errant stem-like cell may be mo...

New test to detect rare proteins in blood

...lready-diagnosed breast cancer patients to monitor recurrence or treatment effectiveness. "The critical issue ...lly reoccur," says Greene. Detection of very early recurrence is important and Greene feels the power of this technology will facilitate recognizing early phases ...

Antioxidant selenium offers no heart-disease protection

...mine if selenium supplementation could prevent the recurrence of non-melanoma skin cancer. Results of the trial, the only large randomized clinical trial to date to examine selenium supplementation alone in the prevention of CVD, appear in the April 15 issue of the American Journal of Epidemiology. Saverio S...

Magnetic probe successfully tracks implanted cells in cancer patients

...es such as vaccines to treat cancer or prevent its recurrence or stem cells to repair damaged organs, say the researchers. Bulte and a team of Dutch researchers used MRI and a magnetic probe approved by both European and U.S. agencies to locate therapeutic cells injected into eight melanoma patients. "Our r...

Vaccine targets tumors where they live

...stable. One patient remained alive without disease recurrence for 59 months after vaccination without any other therapy. This approach may be useful for altering the tumor environment in order to induce anti-tumor immunity and provides a foundation upon which other vaccine strategies can be contemplated for loc...

Genes linked to treatment resistance in children with leukemia

...otype was associated with hematological relapse, a recurrence of the cancer in the blood and bone marrow and the most common reason for treatment failure in childhood ALL. This risk was further increased if the child also had a TYMS 3/3 genotype. No genotype was associated with hematological relapse among patie...

AACR Favors 'full spectrum of stem cell research biology'

... tumors, raising the prospect of eliminating tumor recurrence following initial treatment and developing cancer therapies that are truly curative. # Embryonic stem cells' ability spontaneously to form tumors should not hinder the progress of stem cell research, since these cells will be used only as precursors...

One bacteria stops another on contact

...ems to go away for awhile, then something triggers recurrence of the disease. Work by Scott Hultrgen at Washington University has indicated that E. coli cells may hide in the walls of the bladder and urinary tract in a dormant state, explained Low. It is possible that the newly discovered CDI system contribut...

Scientists turn tobacco against cancer

...d in treating metastatic disease and in preventing recurrence in certain high-risk patients. But the technology to produce large amounts of antibody is expensive, and researchers would like to find alternatives. Dr. Koprowski, Dr. Ko and their co-workers had previously shown that tobacco plant-made monoclonal a...

New Finding May Aid Adult Stem Cell Collection

...er said. And if it helps to prevent the spread and recurrence of STDs, patient-delivered partner treatment could be a valuable tool to add to the physician's black bag. ...

Measurement Challenges In Detecting Cancer Biomarkers

...er said. And if it helps to prevent the spread and recurrence of STDs, patient-delivered partner treatment could be a valuable tool to add to the physician's black bag. ...

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