Tool developed to silence genes in specific tissues using RNAi
...perform all the work of the cell. RNAi, therefore, recognizes the double strand of viral RNA as different, and sets in motion cell machinery that destroys the invading RNA. This involves cutting up the double-stranded RNA, separating it into single strands, and destroying other single-stranded RNA molecules tha...Chemical guidance of T cells leads to immunologic memory and long-term immunity
...ue surface protein called a T-cell receptor, which recognizes only specific antigens (pieces of virus or bacteria that trigger the immune response). During an infection, CD8+ T cells that recognize antigens from the infecting pathogen are activated. These antigen-specific CD8+ T cells expand into a large popula...Illinois pig to make history as source of first complete swine genome
...d through its National Research Initiative -- also recognizes the success of the university's participation in the Livestock Genome Sequencing Initiative (LGSI), also funded by the agency, said IGB Director Harris Lewin. "It's truly gratifying to have the USDA acknowledge the efforts of our LGSI and our nation...Scientists seek to unwrap the sweet mystery of the sugar coat on bacteria
...rate coating is critical in how your immune system recognizes bacteria." Mahal and graduate student Ken Hsu report their findings in the advance on-line edition and March issue of Nature Chemical Biology. The scientists studied the sugar coats of four strains of bacteria: two lab strains of E. coli, one path...In the mind's eye: How the brain makes a whole out of parts
...urnal Neuron. The question of how the brain sees, recognizes and understands objects is one of the most intriguing in neuroscience, associate professor and paper co-author Charles E. Connor said. "This may not even seem like a scientific question to some people, because seeing is so automatic and we are so g...Anthrax inhibitor counteracts toxin, may lead to new therapeutics
...the Rensselaer-Toronto team is also polyvalent and recognizes these surface patterns on the anthrax toxin molecular structure, allowing it to bind at multiple sites and become four orders of magnitude more potent than an inhibitor that binds to a single site. "Think about how two Lego blocks snap together. A ...Hooked on fishing, and we're heading for the bottom, says scientist
...tigious 2005 International Cosmos Award. The award recognizes exemplary research that "promotes the harmonious co-existence of nature and mankind." Dr. Pauly, 59, has authored or co-authored more than 500 scientific articles, book chapters and shorter contributions, and authored, or (co-)edited about 30 books a...Greasing interferon's gears may pave way to greater therapeutic benefits, fewer side effects
...selected as the journal's Paper of the Week, which recognizes the top one percent of the journal's papers in significance and overall importance. The development of a mechanism to tweak Stat1's responsiveness may prove particularly useful for patients with such disorders as hepatitis C, multiple sclerosis and...First big influenza genome study reveals flu evolution
...re dramatically. The human immune system no longer recognizes the virus, and infection begins anew. Steven Salzberg, senior author of the Nature paper, says the new work illustrates this chain of molecular events. "The study demonstrates that these influenza subpopulations, or variant strains, represent a po...Earliest European Farmers Left Little Genetic Mark On Modern Europe
...s,?he added. Impact of HIV treatment The report recognizes that access to HIV treatment has improved markedly over the past two years. More than one million people in low-and middle-income countries are now living longer and better lives because they are on antiretroviral treatment and an estimated 250 000 t...2005 AIDS figures released by WHO and UNAIDS
...s,?he added. Impact of HIV treatment The report recognizes that access to HIV treatment has improved markedly over the past two years. More than one million people in low-and middle-income countries are now living longer and better lives because they are on antiretroviral treatment and an estimated 250 000 t...Removing egg from nest may help save endangered whooping crane
...n is lowest when eggs are removed, says Boyce. He recognizes the need to minimize human influence in national parks, but says priority should be given to ensure persistence of threatened and endangered species so that diversity is not lost permanently. "Surely we cannot appreciate benefits to ecological-proces......h one another, in bacterial congress. The plasmid recognizes organic compounds called phenols that leak out of damaged cells when a plant is wounded. A bacterial protein called VirA acts like an antenna, detecting phenols in a plant wound; the phenols, in turn, signal VirA to add a phosphate (PO4) group to a r...New classification of eukaryotes has implications for AIDS treatment, agriculture and beyond
... disease-causing organisms. The new classification recognizes 6 major clusters of organisms, rather than the 4 traditional Kingdoms. Here are three examples. 1) Pneumocystis, an opportunistic pathogen causing mortality in AIDS patients and immunocompromised individuals, is now known to be a fungus, indicating...Rutgers to lead $52.7 million protein research program
...of New Jersey. "Federal funding of this magnitude recognizes the caliber of our faculty and the quality of their research, and positions us for broader collaborations with other institutions and industries in New Jersey and beyond. The NESG, and other major programs at Rutgers in structural and computational b...Yale scientists identify structure for RNA quality control
...r autoantigen in patients with autoimmune disease, recognizes misfolded RNAs, creating a RNA quality control sys...ealed two distinct RNA binding sites, one of which recognizes misfolded small RNAs. Unlike most proteins, Ro has a hole through the middle - and the hole is used ...Study: Plants use dual defense system to fight pathogens
...he immune pathways that interested the researchers recognizes what they call pathogen-associated molecular patte... the pathogen's effector proteins. If an R-protein recognizes a pathogen's presence, it usually induces a very strong immune response, in most cases stopping a wo...Breast tumors in mice eradicated using cancer vaccine
...ave found that by doing this the immune system now recognizes regions of the HER-2/neu molecule that are not immunogenic when presented by other vaccine approaches. Paterson first hit on the idea of using Listeria as a cancer vaccine vector over ten years ago. "It took a while to dissect what elements of an i...Researchers seek to discover what really happens when a virus enters the body
...mples she uses to support her thesis that the body recognizes some invading substances are not dangerous include the development of a fetus during a woman's pregnancy and the production of milk by lactating women. So the question remains: do we really know what a body's host cell does when a virus infects it?......n S. Hershey Medical Center. "We believe that AAV2 recognizes that the cancer cells are abnormal and destroys them. This suggests that AAV2 has great potential to be developed as an anti-cancer agent." The study was presented June 20, 2005, at the 24th annual meeting of the American Society for Virology held J...