Bioinformatics reveals new gene regulation system
...kwards ?a common feature of DNA sequences that are recognized by regulatory molecules. They designated the sequence the NrdR-box. Because the signal was found in so many diverse groups of bacteria, the researchers thought it might represent a universal regulatory mechanism. The next question was whether the si...Where Bacteria Get Their Genes
...sfer, unique to the bacterial world, has long been recognized as common. But until now scientists did not know which of a bacterium's genes came from lateral gene transfer and which had been inherited from its parent. In their study, the scientists focused on the best-studied group of bacteria, the Gamma-Prote...Scientists discover global pattern of big fish diversity in open oceans
... though space and time. It reveals that some areas recognized today as good fishing are perhaps even more important than we realize ?which makes it all the more urgent to protect these last remaining bits, say the authors. Today the east coast of the U.S., just south of Cape Hatteras and along the east coast o...Tamoxifen-like drug suggests new ways to selectively block estrogen
...llcome, hence the name GW5638. McDonnell, at Duke, recognized its potential and demonstrated efficacy in animal models of tamoxifen-resistant breast cancer. The drug has completed initial phase I clinical testing and has garnered significant interest from the pharmaceutical industry. ...New vaccine means bye-bye to bacteria in the lung
...aeruginosa, called OprF, which had previously been recognized as a promising vaccine candidate. This region of the bacteria was expressed in the capsid area of the vector. Immunization of mice with this vaccine induced antibody production and protected the mice from exposure to a deadly dose of the bacteria. Im...Alien woodwasp, threat to US pine trees, found in N.Y.
... stumbled across the specimen of S. noctilio . "I recognized it immediately," says Hoebeke, a taxonomic expert who has examined tens of thousands of insects sent to him from agencies and scholars over the past 25 years. "I'm always on the lookout for exotics -- for any species that are not yet established in t...Second messenger NAADP shows fast, dose-related impact on satiety cycle
...e notes, Viagra is the world's most successful and recognized secondary messenger targeting drug to reach the market. Cholecystokinin, a first messenger, activates NAADP; so which is 'therapeutic?' Several earlier drugs designed for obesity treatment were chosen because they released a chemical ?the hormone s...Disabling gene defuses rheumatoid arthritis in mice
...d instability. Rheumatoid arthritis has long been recognized as a condition that involves defensive cells from ...sically, everyone thought that the T cells somehow recognized something specific in the joint like collagen or some other protein and attacked it," Peng explains....Some Brain Cells Change Channels
...hough the cells' channel-changing ability has been recognized for a few years, the key players controlling it hadn't been identified. Now, by studying mice, the Hopkins team has identified two proteins, called PICK1 and NSF for short, that help replace channels that let charged calcium ions in with another kind...Researchers test new therapy for advanced melanoma
...es the immune system formed a memory response that recognized the melanoma cells as foreign and prevented tumor regrowth. "We were very encouraged by the results of the preclinical studies." Dr. Heller said. "We're hoping this translates into a beneficial treatment for patients." The Phase 1 clinical trial by...Embryonic Stem Cells Treated With Growth Factor Reverse Hemophilia In Mice: UNC Researchers
...lls robustly engraft within the liver and were not recognized by the immune system as foreign. "Within a few weeks, PEPs became hepatocytes," Fair added. "They went from something that is a very early grandparent of the hepatocyte to becoming hepatocytes. After 115 days, nearly four months after injection, mic...Where bacteria get their genes
...sfer, unique to the bacterial world, has long been recognized as common. But until now scientists did not know which of a bacterium's genes came from lateral gene transfer and which had been inherited from its parent. In their study, the scientists focused on the best-studied group of bacteria, the Gamma-Prote...Newly Discovered 'Branding' Process Helps Immune System Cells Pick Their Fights
...ls select and present chemically modified peptides recognized by unique CD4 T cells. Proceedings of the National Academy of the Sciences, 102 (22), 7928-7933. Funding from the National Institutes of Health and the Kilo Diabetes and Vascular Research Foundation supported this research. ...Distributed Basic Local Alignment Search Toolkit (W.ND-BLAST)
...r to rinse medical equipment is increasingly being recognized as a significant source of microbes that may contribute to many of these life-threatening infections. Infection control practitioners, scientists and epidemiologists convened to review this problem at the annual meeting of the Society for Healthcare...New strategies to reduce hospital-aquired infections
...r to rinse medical equipment is increasingly being recognized as a significant source of microbes that may contribute to many of these life-threatening infections. Infection control practitioners, scientists and epidemiologists convened to review this problem at the annual meeting of the Society for Healthcare...Habitat use by North Pacific right whales, Eubalaena japonica, in the Bering Sea and Gulf of Alaska
...only a few dozens. Recently these whales have been recognized as a different species from right whales seen in the North Atlantic and others in the Southern Hemisphere. To help define areas and ecological parameters critical to the survival of this remnant population of right whales, habitat use was investigat...Genpathway and Baylor College of Medicine Identify New Genes in Breast Cancer
...uck's group previously showed that each odorant is recognized by a combination of receptors, and that each recep...ted to find out whether inputs from receptors that recognized the same odorant are all targeted to the same places in the cortex, producing a distinctive spatial ...Decoding the logic of olfaction
...uck's group previously showed that each odorant is recognized by a combination of receptors, and that each recep...ted to find out whether inputs from receptors that recognized the same odorant are all targeted to the same places in the cortex, producing a distinctive spatial ......de Children’s Research Hospital is internationally recognized for its pioneering work in finding cures and saving children with cancer and other catastrophic diseases. Founded by late entertainer Danny Thomas and based in Memphis, Tenn., St. Jude freely shares its discoveries with scientific and medical communi......hough the cells' channel-changing ability has been recognized for a few years, the key players controlling it hadn't been identified. Now, by studying mice, the Hopkins team has identified two proteins, called PICK1 and NSF for short, that help replace channels that let charged calcium ions in with another kind...