Molecular DNA switch found to be the same for all life
...ational changes in theDnaA-like core of the origin recognition complex. This study was led by Botchan and Nogales... by a single complex of proteins called the origin recognition complex (ORC). However, until now, models of the ORC proteins have lacked sufficient detail to iden......o identify operating principles to probe molecular recognition events with luminescence measurements. These find... electron transfer can be exploited to transduce a recognition event into a significant change in the luminescence of a quantum dot. This research proves this imp...Researchers uncover new mechanism of tumor suppressor
...irst study, Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2, was conducted in Kutateladze's laboratory with the assistance of graduate student Pedro Peña and research assistant Foteini Davrazou. Other co-authors include Rui Zhao, PhD, an assistant professor in the UCDHSC Departmen...FSU biologists uncover mechanisms that shape cells for better or worse
...l communication occurs in this model system." In recognition of groundbreaking work to-date by the FSU scientists -- and to further the understanding of the mechanisms involved in cell-cell communication leading to oocyte polarity -- the National Institutes of Health have awarded Deng a highly competitive "R01...Purdue creates new low-cost system to detect bacteria
...ment to identify a person's face using specialized recognition software," Rajwa said. "You could describe the fac...ell the colony fits the template, and then pattern recognition software is used to classify the bacteria. "One of the most important developments is being able t...Mice lacking key immune component still control chronic viral infections
...at summon other defensive measures. To enable this recognition process, other cells regularly chop up viral prote...egies that they use to block the classical antigen recognition processes that rely on MHC Class I," Virgin says. Follow-up studies now underway have produced pre...Role of protein in immune response may aid HIV research
...overy of the protein called PGLYRP ? peptidoglycan recognition proteins ? earlier this year. Patients, such as those with HIV/AIDS, are susceptible to bacterial infections that are easily averted by people with healthy immune systems but are life-threatening to people with impaired systems. Drs. Dziarski an...Mystery solved: Gold's power against autoimmune diseases defined
...sentation of these pieces alerts other specialized recognition cells of the immune system called lymphocytes, which starts the normal immune response. Usually this response is limited to harmful bacteria and viruses, but sometimes this process goes awry and the immune system turns towards the body itself causing...New weapon in battle against osteoporosis
...from this distressing illness in Germany alone. In recognition of the importance of her results, Dr. Meliha Karsak from the Bonn-based Life & Brain Center has recently been awarded the Osteology Prize of the German Society for Endocrinology, which entails a cash award of 8,000 euros. Her study will now be p...Although the human brain is skilled at facial recognition and discrimination, new research from Georgetown U...g faces" but instead uses the same kind of pattern recognition techniques to distinguish between people as it uses to search for differences between other groups o...Enzyme crystal structure reveals 'unexpected' genome repair functions
...ains a domain structurally similar to the mismatch recognition domain of a bacterial DNA repair protein MutS. MutS helps recognize and repair mismatched DNA in E. coli. These two proteins have little sequence similarity. Biochemical assays following this discovery indicate that this domain allows XPB to interact...Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections
...k groups but are widespread and now endemic." The recognition of community-acquired MRSA as a primary cause of skin and soft tissue infections offers implications for prevention and treatment. In the past, Dr. Blumberg says, "skin and soft tissue infections occurring in the community were generally MSSA, and t...Face perception is modulated by sexual orientation
...Of all the visual skills possessed by humans, face recognition is arguably the most developed. Past brain imaging studies have shown that the brain's cortical network for face perception includes regions in visual cortex that process the identification of individuals as well as social cues, such as gaze directio...Rewind, please: Nature paper shows that cell division is reversible
... in cell division, and he has earned international recognition for his work in the area of chromosomal movement and cell cycle control. ...Biologists visualize protein interaction that may initiate viral infection
...on, the dengue virus attaches to the "carbohydrate recognition domain," or CRD, of a key binding protein called DC-SIGN, located on a host cell's surface. Using a powerful imaging tool called cryo-electron microscopy, the biologists took a picture of the virus attached to the CRD shortly after the two joined to...Polymer aids in blood clotting, pointing way to new treatment
...rypanosomatids was a key breakthrough." Docampo's recognition of the acidocalcisome in various organisms has enabled scientists to detect muscle-like motors that operate a variety of movements within cells, said Arthur Kornberg, who won the 1959 Nobel Prize in Medicine or Physiology for discovering mechanisms i...Wound monitor 'sniffs out' infections
...ased multi-technology gas sensor array and pattern recognition system, enabling the rapid analyses of molecules in the air. It is envisaged that the monitor will be take the form of a mobile unit which sits alongside other monitoring equipment next to the patient. Key applications for the device will include mo...Scientists seek to unwrap the sweet mystery of the sugar coat on bacteria
...o catch these rapid changes. "There's a growing recognition of the importance of carbohydrates on bacterial cell surfaces," says Dr. Lara Mahal, lead researcher and assistant professor of chemistry and biochemistry with the Institute for Cellular and Molecular Biology. "The carbohydrate coating is critical in...'Word-vision' brain area confirmed
...euron the results of reading, language, and object recognition tests both before and after the surgery on the 46-... while his performance remained flawless in object recognition and naming, face processing, and general language abilities," reported the researchers. "Such select...Anthrax inhibitor counteracts toxin, may lead to new therapeutics
... also could be useful for creating specific target recognition in biological sensors. The team says their work demonstrates for the first time that liposome-based polyvalent inhibitors are effective in animals and they are continuing development on the anthrax inhibitor through additional animal testing. ...