Long-term changes in experience cause neurons to sprout new long-lasting connections
... dendrites, like twigs from a branch, and form the receiving ends of synapses, which are the junctions between neurons where neurotransmitters are released. The researchers induced a long-term change in the sensory experience of mice by trimming the animals' whiskers, selectively cutting some but leaving neig...High estrogen levels associated with dementia in older men
...nes play a role. One large study showed that women receiving estrogen therapy had an increased risk of cognitive impairment and dementia. However, the evidence for how testosterone levels affect men is contradictory. To better understand the role of sex hormones in dementia, researchers led by Mirjam Geerli...Studies suggest new brain protein may help in treating schizophrenia, insomnia and anxiety
...ion Americans. Animals pretreated with NPS before receiving a drug that normally induces psychotic-like behavi... neurotransmitter that initiates an impulse by the receiving neuron. Currently, the team is looking at whether natural mutations in the genes of NPS and its rece...Production of key Alzheimer's protein monitored for first time in humans
...g was to follow the mental performance of patients receiving the treatment over many months or years. "This new test could let us directly monitor patients in clinical trials to see if the drug is really doing what we want it to do in terms of Abeta metabolism," Bateman says. "If further study confirms the v...Radioactive scorpion venom for fighting cancer
...e low and comparable to those from a family member receiving standard thyroid cancer therapy. Jackson is enc...f the earlier phase II trials showed that patients receiving up to 40 mCi of weekly dose did not show evidence of any adverse reactions attributable to the radia...Ritalin packs punch by elevating norepinephrine, suppressing nerve signal transmissions
...y pathway response to the whisker stimulation when receiving two different doses of methylphenidate. They found that both the low and moderate doses of methylphenidate: Elevated norepinephrine in the area of the brain that processes information related to whisker movement. Norepinephrine helps transmit senso...Cancer virus protein needed for successful infection
...ing p13 remained uninfected, while all six rabbits receiving cells with normal HTLV-1 became infected. "Our findings are the first to indicate that the HTLV-1 p13 protein plays an essential biological role during the early phase of virus infection in an animal model," Lairmore says. Next, the researchers w...Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection
...er than those in control groups. In fact, of those receiving BM-NSC-IL-23, 60 percent survived beyond day 120 tumor-free. Only 20 percent of those treated with IL-23 that was not attached to neural stem cells survived, and no animals survived if they received neural stem cells without IL-23. Even after additi...Protein found to control tumor growth in certain breast cancers
...D mice to accelerate tumorigenesis. In those mice receiving Nod1 cell lines tumor growth did not occur even in the presence of estrogen pellets, indicating that Nod1 acts as an effective cellular brake on estrogen-dependent tumor growth. In addition, the presence of Nod1 reduced the expression of the natural...Newly discovered killer cell fights cancer
...ich received injections of IKDCs, but not in those receiving conventional NK cells only. Evidence from the shrunken tumors revealed certain "cell-killing" proteins that could be traced to IKDCs. These results are published separately in Nature Medicine. Housseau's group is conducting further studies to veri...Stem cell transplants improve recovery in animal models for stroke, cerebral palsy
...anted cells were present two months later, animals receiving treatment developed new neurons, apparently formed from endogenous stem cells. "The mechanism that we are putting forward is these donor cells are secreting nourishing trophic factors that are helping the host brain cells survive and stimulating ste...Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections
...aph skin and soft tissue infections among patients receiving care at the Grady Health System (Grady Memorial Hospital and its affiliated outpatient clinics in Atlanta) are now due to MRSA. The vast majority of these MRSA skin and soft tissue infections are due to a single clone or strain of MRSA called USA300...All placebos not created alike
...ream). In the second phase of the study, patients receiving sham acupuncture reported a more significant decrease in pain and symptom severity than those receiving placebo pills for the duration of the trials. The results of this study show that the placebo effect...Protein receptor cools passion of 'kiss and run' nerve cells
... targets the mechanism to modify release." On the receiving cell, the post-synaptic side, there is a range of protein receptors that vary in sensitivity to the amount of neurotransmitter that's released. Some scientists think if the release of neurotransmitter can be controlled to take into account the sensit...Nobelist discovers antidepressant protein in mouse brain
... which bind to receptors located on the surface of receiving cells. Serotonin selective reuptake inhibitors (SSRIs), medications commonly prescribed for anxiety and depression, compensate for reduction in serotonin signaling by boosting levels and binding of serotonin to receptors. Previous studies have sugges...One in 14 men having a heart attack drive themselves to hospital
...e time it takes them to get to the hospital and in receiving treatment and being admitted when they arrive. "Women need to be much more aware of the risks they face from heart attacks and the importance of seeking prompt treatment." The team's previous paper, published in the Journal of Advanced Nursing in S...Cyclosporine inhibits hepatitis C virus in vitro
...rgo interferon-ribavirin combination therapy after receiving a liver transplant in hopes of a sustained virologic response. At the same time, of course, the patients must take immunosuppressive agents to guard against transplant rejection. The most commonly used anti-rejection medication is Tacrolimus, altho...New study reveals promising osteoporosis treatment
...Dawley rats (average weight, 160g) into six groups receiving the following diets: control; mineral deficiency-induced osteoporosis (MD); MD supplemented with Mg-CaP; Zn-CaP; F-CaP; and Mg/Zn/F-CaP. Each supplement was 0.6% of the MD diet. The post-mortem examination of the femurs in the MD Mg/Zn/F-CaP group sh...Major WHO study concludes calcium supplements can reduce complications during pregnancy
...ple. By one estimate, about 50 percent of patients receiving antiretroviral therapy in the United States harbor HIV viruses that are resistant to at least one of the available drugs. In fact, people with an infection typically have a diverse array of HIV mutants, some of which are resistant to antiviral drugs.......ple. By one estimate, about 50 percent of patients receiving antiretroviral therapy in the United States harbor HIV viruses that are resistant to at least one of the available drugs. In fact, people with an infection typically have a diverse array of HIV mutants, some of which are resistant to antiviral drugs....