Stem cells engage in dialogue with the cells that regulate their futures
...ave the niche. The researchers also found that the receiving end for the Notch pathway, the trigger, is required in the niche cells, making them receivers of signals, not just senders. Work by other scientists had shown that TCF-beta signaling from niche cells is required to maintain active stem cells. "Our...Intravenous gene therapy protects normal tissue of mice during whole-body radiation
...mber of the population would die within 30 days of receiving a large dose of radiation to the entire body. In the study, mice were used to test the protective effects of manganese superoxide dismutase plasmid liposome (MnSOD-PL) gene therapy on the bone marrow during whole-body irradiation. The researchers ...HIV-1 kills immune cells in the gut that may never bounce back
...have to be re-examined, with HIV-positive patients receiving colonoscopies earlier and perhaps more frequently than current recommendations allow. In the laboratory, these findings should give researchers another angle with which to approach HIV vaccines. "What good is a vaccine going to be if you get immu...LSD treatment for alcoholism gets new look
...alcoholics quit drinking for the same period after receiving group therapy, and less than 12 per cent quit in response to traditional psychotherapy techniques commonly used at that time. Published in the Quarterly Journal for Studies on Alcohol, the 1962 study was received with much skepticism. One research...Cocaine high caused by interference in neuronal receiving stations
...ed the effect to interactions between two types of receiving stations in neurons for nerve signals from their n...eurotransmitters activate protein receptors on the receiving neurons, which induce the nerve impulses in the receiving cell. These receptors also adjust themselv...Researchers identify new weapon to fight deadly bacterial sepsis
...therapy for organ and bone marrow transplants, and receiving high-dose chemotherapy for cancer. Young children and elderly people are also at a higher risk for the condition because of their weaker immune systems. Now, Assistant Professor Kota V. Ramana and Professor Satish Srivastava of the University of T...Rescuing injured hearts by enhancing regeneration
...iac wall and the least amount of scarring. Rats receiving only the p38 MAP kinase inhibitor had increased pr...had improved heart function at three months. Those receiving only FGF1 maintained their functional improvement, but did not show as much cell proliferation as th...New study suggests promising drug combinations for sleeping sickness
...he death rate was much higher amongst individuals receiving one of the combinations, so the trial was stopped. In the trial, the cure rate for nifurtimox-eflornithine was over twice that for melarsoprol-nifurtimox and substantially higher than that for melarsoprol-eflornithine. The rates of adverse even...T for two: Scientists show how immune system chooses best way to fight infection
...ction. Regulatory T cells, if given to individuals receiving transplants, may help suppress the rejection response. Now, a team of researchers has discovered a novel mechanism determining whether a maturing T cell is likely to emerge from the thymus as an effector cell or a regulatory cell. The research sug...Replacing insulin is top-ranked breakthrough foreseen for health in developing world
... a particular regenerative medicine application is receiving in industrialized nations. However, as highlighted in the 2005 report of the UN Task Force on Science, Technology, and Innovation, domestic innovation by developing countries is important as it is more likely to be targeted towards local health need...New research shows big improvement in survival after stroke
... patients were being admitted to hospital with 90% receiving scans. This improved level of stroke care has directly benefited stroke sufferers across New Zealand." However, as the death rate declines, there has been a significant increase in the number of patients with an impaired level of consciousness an...Poor athletic performance linked to vitamin deficiency
...daily allowances set by the U.S. government may be receiving lower amounts of nutrients than there bodies need, said Manore. Athletes who restrict calories or limit food groups like dairy or meat have an increased chance of deficiency. Such athletes are often concerned about maintaining a low body weight for s...New HIV statistics indicate increasing toll of AIDS on African American community
...are that they have HIV. These individuals are not receiving life-saving medical care and may unknowingly transmit HIV to sex- and needle-sharing partners. In addition, African-Americans are diagnosed at later stages in the disease more often than other racial/ethnic groups, diminishing medications' effective...Experimental cancer drugs counter muscle deterioration seen in muscular dystrophy
...ted, dystrophic mice. Furthermore, dystrophic mice receiving treatment were able to perform physical exercise (e.g. running on a treadmill) similar to normal, non-dystrophic mice. Muscular dystrophy is a group of more than 30 genetic diseases, characterized by progressive weakness and deterioration of skele...First-time analysis reveals millions of Europeans left at risk from influenza
...y one third (35%) of all high risk populations are receiving seasonal influenza vaccine in Europe, resulting in avoidable morbidity, hospitalisations and mortality. For the first time, researchers have attempted to develop a model to enable European public health officials to visualise the need for better i...Effective HIV control may depend on viral protein targeted by immune cells
...and University of KwaZulu-Natal in South Africa is receiving early online release in Nature Medicine. "Unders...s indicating poorer control of HIV. In people receiving no antiretroviral treatment, the improved HIV control associated with Gag-specific CD8 response woul...Brains can recover from alcoholic damage but patients should stop drinking as soon as possible
...ients that managed to abstain from alcohol without receiving any psychotherapeutic medication were included in the study, and those with secondary alcohol-induced disorders, as well as heavy cigarette smokers (more than 10 cigarettes a day), were excluded. Ten healthy volunteers (six men, four women), matched ...Gene therapy for hereditary lung disease advances
...scontinue their replacement therapy 28 days before receiving the gene therapy. One volunteer who had not bee...-1 antitrypsin, which was detectable 30 days after receiving an injection. However, residual levels of alpha-1 antitrypsin from the replacement therapy in the ot...Researchers examine why food tastes bad to chemotherapy recipients
About two million cancer patients currently receiving certain drug therapies and chemotherapy find foods...ems such as persistent metallic tastes of patients receiving chemotherapy. They hope to identify the cause of the metallic flavor in the mouth when drinking wa......s that can occur with food allergy. Instead of receiving shots, as seasonal allergy sufferers do, the subjects were given small doses of powdered egg orally, mixed in food. “We started the subjects with a very small concentration of egg product -- the equivalent of less than one-thousandth of an egg -- and...