Computational verification of protein-protein interactions by orthologous co-expression
...ted high levels of sirtuin1 protein. (Rodgers will receive the Nupur Dinesh Thekdi Research Award on April 14 for this work as part of the School of Medicine's 28th annual Young Investigators' Day celebration.) "When there's no incoming food, muscles make lactate and alanine and send them to the liver to be...Eliminate Data Analysis Bottlenecks in Drug Discovery
...ted high levels of sirtuin1 protein. (Rodgers will receive the Nupur Dinesh Thekdi Research Award on April 14 for this work as part of the School of Medicine's 28th annual Young Investigators' Day celebration.) "When there's no incoming food, muscles make lactate and alanine and send them to the liver to be...While on trail of dioxin, scientists pinpoint cancer target of green tea
...and pains no longer have to chew on willow bark to receive the benefits of the substance salicin ?they simply take an aspirin –the current research opens the door to extending the health benefits first discovered in green tea to people who never touch the beverage. Isolating the chemicals that protect agains...Natural Killers Could Lead to New Hepatitis Treatments
...tream against blood flow. They halt only when they receive a chemical signal to unleash an immune-system assault on marauding microbes, other invaders or damaged tissue. The findings offer a new way of thinking about this important class of immune cell, which is responsible for the inflammation and cell dea...Active Vaccine Prevents Mice From Developing Prion Disease
...ding to the study. By comparison, mice that didn't receive the vaccine survived only an average of 185 days, and all were dead by 300 days. The NYU scientists are in the process of redesigning the vaccine for deer and cattle. After choosing the appropriate bacteria for each vaccine, they must genetically mo...Asymptomatic HIV babies could use earlier treatment
...born later in the study period were more likely to receive triple therapy and less likely to experience AIDS-related complications or death. In fact, none of the 23 children who received triple therapy died or developed AIDS before their third birthday. In contrast, about 55 percent of the children in the fi...Hopkins AIDS experts issue warning about global efforts to provide drug therapies
...me another case where only a few privileged people receive therapy. What international authorities can do is help these countries plan for rationing, so that the medical and ethical mistakes of the past are not repeated." ...Antiretroviral Therapy May Prevent HIV Transmission From Breastfeeding Mothers To Infants
...me period with comparable HIV disease, who did not receive antiretroviral therapy because it was unavailable to them at the time they were breastfeeding. The results indicated that antiretroviral therapy suppresses HIV RNA in breast milk and may therefore reduce mother-to-child transmission of HIV during br...The first impact factor for PLoS Biology ?13.9
... media coverage, and subsequent issues continue to receive regular attention. Content from PLoS Biology has been read, copied, redistributed, and reused, without restriction (aside from proper citation of the authors), and now we know that the journal has also been cited time and time again. PLoS Biology wa...Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine
...re deadly, killing 100 percent of those who do not receive the right antibiotics soon after exposure. "There is," the authors note, "an urgent need for vaccine development." One of this microbe's enduring mysteries has been how it gains a foothold in the host without triggering a protective immune response....New study: Sexually transmitted disease treatment can be effectively administered by sex partners
...r other [STDs] they may have, such as HIV" if they receive treatment for chlamydia or gonorrhea, Dr. Kissinger said. "While this is a valid concern, the alternative to not doing patient-delivered partner treatment is to rely on the patient to refer the partners. We know that that results in less than 50 perc...Measurement Challenges In Detecting Cancer Biomarkers
...r other [STDs] they may have, such as HIV" if they receive treatment for chlamydia or gonorrhea, Dr. Kissinger said. "While this is a valid concern, the alternative to not doing patient-delivered partner treatment is to rely on the patient to refer the partners. We know that that results in less than 50 perc...New Finding May Aid Adult Stem Cell Collection
...r other [STDs] they may have, such as HIV" if they receive treatment for chlamydia or gonorrhea, Dr. Kissinger said. "While this is a valid concern, the alternative to not doing patient-delivered partner treatment is to rely on the patient to refer the partners. We know that that results in less than 50 perc...Morphine for Chest Pain Increases Death Risk
...s that patients given morphine were more likely to receive evidence-based medicine, were more likely to be treated by a cardiologist and were more likely to receive an invasive cardiac procedure." Meine recommended that physicians with hospitalized heart attack pa...Scalpel-free surgery could reduce risk of HIV and hepatitis exposure for health care workers
...operations. As many as 87 percent of surgeons will receive an injury that breaks the skin -- thus allowing for possible disease transmission - at some point in their career. There are an estimated 40,000 new cases of HIV each year, and hepatitis C is increasing at an even faster rate, according to the report......g to the muscles to take the appropriate action to receive the reward. Computer models of how a bee assimila... for a simple behavior or if a person must work to receive the reward. His discovery is one of many that renowned neuroscientists in La Jolla have conveyed in...Drug Offers Alternative to Surgical Treatment After Miscarriage
... failure. Of these, 491 were assigned at random to receive misoprostol. The rest of the women underwent vacuum aspiration. The women in the misoprostol group were treated with 4 vaginal doses of misoprostol, each containing 200 mcg. of the drug. If the uterus had not expelled its contents by the end of three...Sleeping Sickness Epidemic Spreading in Uganda
... failure. Of these, 491 were assigned at random to receive misoprostol. The rest of the women underwent vacuum aspiration. The women in the misoprostol group were treated with 4 vaginal doses of misoprostol, each containing 200 mcg. of the drug. If the uterus had not expelled its contents by the end of three...Unexpected lock and key mechanism found for the assembly of tumor blood vessels
...When the integrin meets with VCAM, both cell types receive survival signals at this active stage of blood vessel development, which occurs mainly in tumors in adults," said Varner. "This was a chance discovery, which was exciting, and we think it may have important clinical significance." In their current s...