Flick of whiskers helps tease out brain's 'shadow' signaling system
...f the brain. "Our take on this is that astrocytes really are part of higher brain function," said Nedergaard, noting that astrocytes are much more complex in people than in rodents, while neurons aren't that much different ?just longer. "For years, people have considered the astrocyte like a housekeeper t...New strategy rapidly identifies cancer targets
...ome high-throughput DNA sequencing, and we weren't really finding much," he said. Instead, the team added tools from the burgeoning field of proteomics, the study of proteins. "We decided this more functional assay would get us to the disease-causing genes more rapidly," said Druker, who has been studyin...Mussels evolve quickly to defend against invasive crabs
...ass. "The consistency over two years and two sites really suggests an underlying robust mechanism," says Byers, who is Freeman's dissertation advisor. While this sort of rapid evolutionary response to predators has been exhibited in some other species, all have been vertebrates. The blue mussel, which Fre...New light microscope sharpens scientists' focus
...in is located is nice," Betzig said, "but what you really want to know is where multiple proteins are in rel...f we can begin to refine this technique, we should really be able to take it to a lot of new applications." ...Cornell researchers find serious fish virus in Northeast for first time
...we're talking about the lower Great Lakes -- there really is no treatment," said Bowser. "The best management option is to try and contain the spread of it as best we can." Hot summer weather impacts how the virus spreads because warmer water can stress fish, thereby lowering their natural defenses and ma...A new tool against brain disease
...n adjustment to try to co-exist," he said. "But we really do not know at this point." Walker emphasized that the study could not have been done without his group's ongoing collaboration with the University of KwaZulu Natal. "These are studies that simply could not have been done in the United States,...How HIV 'exhausts' killer T cells
...n adjustment to try to co-exist," he said. "But we really do not know at this point." Walker emphasized that the study could not have been done without his group's ongoing collaboration with the University of KwaZulu Natal. "These are studies that simply could not have been done in the United States,...... -- the snake. "A snake is the only predator you really need to see close up. If it's a long way away it's not dangerous," Isbell said. Neurological studies by others show that the structure of the brain's visual system does not actually fit with the idea that vision evolved along with reaching and gras...UF scientists restore sight to chickens with blinding disease
...chick. "The process sounds straightforward but it really isn't," Semple-Rowland said. "It took quite a long time to build the vector, develop the injection procedure and figure out how to hatch the eggs. By doing the injection early during development, we actually treat the cells before they become photore...Stanford doctors advance in bid to turn mice stem cells into blood vessels
...ow them into contracting myocytes in cultures: You really see them contracting, you really know they're alive, and you start to believe this stem cell stuff has possibilities." For the study...How satellite tracking revealed the migratory mysteries of endangered Atlantic loggerhead turtles
...ow complicated the migration of marine vertebrates really is and how sophisticated our conservation efforts must be to safeguard these animals. Given the range these reptiles can cover an international cooperative effort in seven African states is needed to create a strategy that would protect them." Resea...MIT 'seeing machine' offers hope to blind
...ed all 10 "word-images" correctly. "They responded really well to the visual language," Goldring said. "One woman told me she would love to see recipes written that way." They also used the machine to navigate through a virtual environment, raising the potential for "previewing" unfamiliar buildings a pers...Cigarette smoke blocks cell repair mechanism, University of Florida study shows
..., he said. "Some of these cells that survive are really acquiring true mutagenic characteristics," Narayan said. "A defect in only one cell is important for growth of a full-blown tumor. You don't need 1,000 or 1 million cells to be affected. Only a single cell which may have genomic instability due to co...Ever-happy mice may hold key to new treatment of depression
...sion' in animals," says Dr. Debonnel. "The results really surprised us; our 'knock-out' mice acted as if they had been treated with antidepressants for at least three weeks." This research represents the first time depression has been eliminated through genetic alteration of an organism. "The discovery o...Adult stem cells are touchy-feely, need environmental clues
...onment might limit the fate of stem cells, I never really thought that it would be sufficient to direct cell fate," said Lee Sweeney, a coauthor of the study and chairman of Physiology in Penn's School of Medicine. "When I saw Adam's first images, I was stunned to see that the physical environment alone wa...First 'encyclopedia' of nuclear receptors reveals organisms' focus on sex, food
...ers centered on reproduction and metabolism. So it really is all about sex and food. "The power of this a...hat may predict functions heretofore unknown. This really is pointing to new directions in biology." Much already is known about individual nuclear receptors...Mechanism identified for promising neurological drug
...nce of inflammation. However, says Swanson, "it's really been unclear up till now how minocycline works to prevent the inflammatory response." Swanson credits the study's lead author, Conrad Alano, PhD, assistant professor of neurology at SFVAMC and UCSF, with the insight that the action of minocycline cl...Bones hold the key to blood renewal
...in the June issue of Nature Medicine. Bones are really two systems in one. The cavities inside bones are filled with spongy bone marrow, in which stem cells divide and their daughter cells differentiate into all kinds of blood cells, including large numbers of immune cells for the body's defense. The hem...New lab technique churns out fungus' potential cancer fighter
...ets researchers finally produce enough rasfonin to really start investigating how it functions, and how we might harness it to fight cancer." In 2000, researchers from Chiba University in Japan and the University of Tokyo simultaneously discovered a compound in certain fungi that selectively destroyed cell...Chewing up a key regulator of fat synthesis keeps mice lean despite a high-fat diet
...emistry was clearly satisfying for Montminy. "What really made this an interesting story is that the molecular mechanism and the biology intersected since we were able to explain how TRB3 made the mice lean," he reflects. "That doesn't happen very often." Additional contributors to this study included ass...