Achilles heel of the herpes virus possibly found
...one end of the protein exposed outside of the cell ready to link up with viruses -- or to serve the receptor's "real" function, which still remains to be discovered. They also showed that HSV does not enter into pig cells that have an altered human B5 protein that is changed by mutations that affect a func...Say what? Bacterial conversation stoppers
... can mimic the power of a multi-cellular organism, ready to face challenges too daunting for an individual microbe going it alone. Swelling populations trigger their quorum-sensing apparatuses, which have different effects in different types of bacteria. One species might respond by releasing a toxin, whil...MicroRNA tweaks protein that controls early heart development
...in levels. You can imagine a pool of messenger RNA ready to make a protein, and by virtue of a microRNA, that protein synthesis can immediately be shut off and turned back on based on a cell's environment or its needs at the time." Dr. Yong Zhao, a postdoctoral researcher in Dr. Srivastava's lab at UT Sou...Scientists find a maturity gene in fly
...their bodies. "How does an animal know when it is ready to mature ?what determines that time?" Thummel asks. "That's a big question of which we have poor understanding. This gene, DHR4, controls the time at which the animal begins to mature. It also plays an important role ?along with many other genes ?du...MWG Biotech expands siMAX?siRNA portfolio with new scales, lengths and design tools
...their bodies. "How does an animal know when it is ready to mature ?what determines that time?" Thummel asks. "That's a big question of which we have poor understanding. This gene, DHR4, controls the time at which the animal begins to mature. It also plays an important role ?along with many other genes ?du...Mosquitoes are more attracted to individuals infected with malaria
...biting behaviour of the mosquito vector when it is ready for a new host. Such manipulation could have a profound effect on the epidemiology of disease and, if it is not considered, could lead to severe biases in the estimates of the intensity of malaria transmission. Citation: Lacroix R, Mukabana WR, Goua...New study finds how cells with damaged DNA alert the immune system
...g-term memory of prior invaders. These cells stand ready to find and destroy cells infected by viruses before the virus can spread. "We don't have direct information about the role of the DNA damage pathway in regulating immune responses to infectious diseases, but given what we have shown here, it is cer...Renewed hope for Parkinson's patients
...g-term memory of prior invaders. These cells stand ready to find and destroy cells infected by viruses before the virus can spread. "We don't have direct information about the role of the DNA damage pathway in regulating immune responses to infectious diseases, but given what we have shown here, it is cer...UW scientists report a new method to speed bird flu vaccine production
...e quantities. The new technique promises to ensure ready generation of seed strains for the production of vaccines required to blunt the spread of influenza. In the event of an outbreak of especially virulent strains of influenza, such as the H5N1 or "bird flu" viruses now being monitored by scientists, an...Mammalian Transcriptome Mapped
...d the RNA transcripts would be like dubbed copies, ready to play. One big surprise about the recent transcriptome results is the amount of noncoding RNA expressed in cells. (Noncoding RNA does not encode for proteins and therefore does not fit into the classical definition of a gene.) While Wahlestedt and...Normal chromosome ends elicit a limited DNA damage response
...ow right after DNA replication, when the cell gets ready for cell division, chromosome ends are exposed," says research fellow and first author Ramiro Verdun who emphasizes that, "it would be very unhealthy for the cell if it happened at any other time." In addition, Verdun and his colleagues found that s...New view of cancer: 'Epigenetic' changes come before mutations
...genitor genes. This leads to a population of cells ready to cause new growth. The second step involves an initiating mutation within the population of epigenetically disrupted progenitor cells at the earliest stages of new cell growth, such as the rearrangement of chromosomes in the development of leukemi...Cells from amniotic fluid used to tissue-engineer a new trachea
...hs before birth and a tissue-engineered patch made ready for use soon after delivery. His team is also working on stem-cell-based, tissue-engineered grafts to fix spina bifida (in which the spinal column doesn't close fully during fetal development) and structural cardiac defects, using similar principles....Cord blood cells may widen treatment window for stroke
...r treatment criteria, smaller hospitals often lack ready access to a CT scan, a test needed to rule out a hemorrhagic stroke caused by a burst blood vessel. The drug can worsen this less common type of stroke. "New and more flexible treatments are needed to help more patients," Dr. Willing said. "Cord blo...Johns Hopkins flu expert calls for mandatory vaccination of health care workers
...is based on research showing that despite free and ready access to the vaccine, only 40 percent of all health care workers actually get a flu shot. "We have gone as far as possible with vaccination programs emphasizing education and health promotion," says Perl, an associate professor of medicine and path...Sleeping sickness parasite shows how cells divide their insides
...two complete structures, and associated Golgi, are ready to be allocated to daughter cells. Significant recent advances in the molecular genetics of trypanosomes by Elisabetta Ullu and Christian Tschudi's group at Yale, allowed direct manipulation of protein levels using the innate RNA interference (...3D ultrasound device poised to advance minimally invasive surgery
...n human patients, but its success in dogs makes it ready for clinical trials, according to the researchers. Endoscopic surgical methods have the advantage of reduced postoperative pain and a faster recovery. However, the two-dimensional ultrasound imaging now available offers surgeons only a limited view...Rare Tibetan antelope listed as endangered
...n human patients, but its success in dogs makes it ready for clinical trials, according to the researchers. Endoscopic surgical methods have the advantage of reduced postoperative pain and a faster recovery. However, the two-dimensional ultrasound imaging now available offers surgeons only a limited view...Clawed frog helps Fanconi anemia research make leaps
...nient extract rich in all the essential components ready for full replication. Then, by chemically activating the extract and adding sperm DNA from the male frog, the proteins in the extract unwind the DNA and the replication process is off and running under the watchful eyes of the researchers. "That'......want to rely on condoms for birth control. I'm not ready for a vasectomy, though. This new procedure could be the answer that gives men the decisive control we lack with current contraceptives." In the RISUG study, doctors inject a gel into the tube that sperm travel through after they are produced (known...