Berkeley researchers lay groundwork for cell version of DNA chip
...s" that reside on the surface of every cell, and a reaction between two types of molecules, a nitrogen-contain...oth cell friendly and precise, so we exploited the reaction to very specifically link a DNA molecule to the surface of a living cell," said Chandra. "DNA is not...A case of mistaken molecular identity
...uals with the tropical disease can shut down a key reaction in the retina, causing night blindness. "This is...tients, we see scarring because there is a complex reaction that causes inflammation," he said. "But there are no such scars in the eyes of Chagas patients with...How low can you go? Ants learn to limbo
...a at one end of a channel. They observed the ants' reaction towards a horizontal barrier placed between the food and the ants' nest using high speed video recordings from the side. They then tracked the ants' movements and did a kinematic analysis of the results. ...Trial success for diabetic nerve therapy
...y adverse event reported being mild injection-site reaction in four of the 12 diabetic patients tested, all of which resolved quickly. "We are delighted by the progress of our clinical programme in diabetic neuropathy and by the reception it has received from the medical and scientific community," said Edwar...... sugars for food). The focus of the research was a reaction that takes place in enzymes in the photosynthetic ...surrounding temperature, the scientists timed this reaction to see how reaction rates changed as things heated up. A general rule for enzyme reactions states ...Pest control research leads to pain control discovery
...rs reverse hyperalgesia and bring their withdrawal reaction back into the normal range. Hammock said "these sEHIs are of similar or greater potency in reducing inflammation in rodents to Vioxx, but also when combined with Vioxx can dramatically reduce the concentrations of the Cox 2 inhibitor needed," Hammo...For Stanford scientists, RNAi gene therapy takes two steps forward, one step back
...sted that RNAi gene therapy might induce an immune reaction or switch off the wrong gene or genes. As these concerns faded, things began looking up for RNAi with three RNAi therapies now in human trials - two for macular degeneration and one for a type of pneumonia. However, these studies involve simply infu...Key stress protein linked to toxicities responsible for Parkinson's, Alzheimer's
...y nitric oxide (NO), causes inhibition of PDI by a reaction called S-nitrosylation, thereby reducing PDI's neuroprotective benefits. This data provides the first molecular link between NO free radicals and protein misfolding, which is currently thought to be a common pathway in the pathogenesis of virtually ...How plants avoid feeling the burn
...molecules, which lie flat on the surface of a tiny reaction chamber, are first picked up by the STM probe's gold tip and chemically bound between these two electrodes, forming a kind of nanoscale bridge. "Gold is a soft metal, and when you pull it apart, eventually, you can measure the conduction of a single ...Rehydrate -- your RNA needs it
...lecule---even far from the site where the chemical reaction occurs---affect the rates at which the enzyme changes conformation and catalyzes the reaction. Something similar had been seen in protein enzymes, but never before in RNA enzymes. The earlier finding, published in PNAS two years ago, suggested tha...Injection may prevent infertility in men receiving cancer chemotherapy
...nificant testicular damage is caused by the immune reaction to it. We hope to begin clinical studies in cancer patients in the next few months." ...Case Western Reserve University researchers find protein associated with brain cell death
...e Case researchers began targeting research on the reaction between the plaque and immune cells. In in vitro studies of brain tissue from mice, the researchers found that the microglia had the appropriate immune response that the plaque was harmful, but then the protein Vav was found to be a component in o...Gene first linked to rare disease may trigger skin cancer, other tumors
...t to be a trigger of cylindromas--sparked the same reaction in the mutant cells, they found. "In the absence of CYLD, it is the accumulation of Bcl-3 that is the problem," Fässler said. "Bcl-3 is normally under tight regulation; it is primarily found out in the cytoplasm, with very little in the nucleus." Cy...Plant protection from cold decoded
...g Zhu has described how a little-known biochemical reaction regulates that genetic cascade. Zhu's findings were published in the May 15 online version of the Proceedings of the National Academy of Sciences in a paper titled The Negative Regulator of Plant Cold Responses, HOS1 is a RING E3 Ligase That Mediate...Small molecule interactions were central to the origin of life
...le organic molecules, multiplied through catalyzed reaction cycles and an external source of available energy.... system," explains Shapiro. "The existence of side reaction paths can provide the network with the capacity of reacting to circumstances." Shapiro outlines how...Allergy battle could be won in five years, says scientist
...h the protective cell layer and block the allergic reaction before it occurs. "The effect will be like avoiding allergens altogether. Removing carpets and rigorous cleaning of homes are established ways to avoid allergens, but they are only partially effective because their effects do not 'travel' with alle...UCI scientists find chlorine may contribute to ozone formation
...formation. The primary cause of urban ozone is the reaction of hydroxyl radical (OH) with hydrocarbons and nitrogen oxides. OH is a highly reactive molecule made of oxygen and hydrogen that forms photochemically in air. "For the last 30 years, we've known that the hydroxyl radical is the primary cause of o...New bird flu drug promises to beat the problem of resistance
... a very different manner, by undergoing a chemical reaction with protein. Furthermore, this chemical reaction only takes place at one specific part of the neuraminidase, a part that is essential for the neurami...Smell of success for nanobiosensors
...animal noses on a microelectrode and measuring the reaction when the proteins come into contact with different...-NOSED project focused on replicating the physical reaction that takes place in animal noses, the project partners are now planning to continue their research a......the name Lamarck or the term soft inheritance, the reaction is, 'Oh my God, here we go again'," Richards says. "But from a molecular biology point of view there is a mechanism to do soft inheritance, and epigenetic inheritance can be construed as a form soft inheritance. That's all I'm saying. The really he...