New engineered drug may offer prolonged arthritis relief
...r mounting the body's immune response and normally react to IL-1 by growing in numbers and releasing molecules that further activate the immune system. Active IL1RA therefore serves to dampen the immune cells' rate of proliferation, Shamji said. White blood cells treated with the modified drug increased ...Molecular 'signature' protects cells from viruses
...al, we ought to understand precisely how the cells react to this genetic material.'...Scientists find new way to manipulate DNA
...rent polymers, and pinpoint exactly how they would react to different flows. Vanapalli is now a post-doctoral fellow at Twente University in the Netherlands. The equation they developed can be applied to design flows that break polymers into certain lengths, or to design polymers to withstand certain fl...Environmental toxins may cause body's defenses to worsen lung disease
...nduced cell damage. "By looking at how the cells react to these stimuli, we hope to gain insight into what triggers and mediates the immune system response," Borchers says. This will help scientists determine which lymphocytes are important for regulating damage in the lungs, so they can develop ways t...Who gives stem cells their marching orders?
...l soup they've manufactured themselves, stem cells react to subtle changes in chemical concentration, moving apart and taking on distinct identities. The million-dollar question: How do these cells ?all initially the same, and exposed to the same environment ?end up acting in such different ways, and in so...Two nerve cells in direct contact
... axis. Interestingly, this cell seems initially to react only to the movements in front of its own eye (ipsilateral), but remain blind to movements in front of the other eye (contralateral). However, if the ipsilateral movement stimuli are combined with the contralateral, it is seen that the latter do inde...New UD technology removes viruses from drinking water
...fection process, this natural organic material can react with chlorine to produce a variety of toxic chemicals called disinfection byproducts. "Our iron-based technology can help ensure drinking-water safety by reducing microbial pathogens and disinfection byproducts simultaneously," Chiu noted. App...Brain works more chaotically than previously thought
...demonstrate that certain cells in the white matter react to glutamate: the precursor to what are known as oligodendrocytes. Oligodendrocytes are the brain's "insulating cells". They produce the myelin, a sort of fatty layer that surrounds the axons and ensures rapid retransmission of signals. "It is likely...Fruit flies and global warming -- Some like it hot
...ia have discovered ways in which fruit flies might react to extreme fluctuations in temperature. Short-term exposure to high heat stress ("heat hardening") has been known to have negative effects on Drosophila. But Loeschcke and Hoffmann discovered that it can have advantages too. Flies exposed to heat har...How to manage forests in hurricane impact zones
...al stands of pine trees, looking at how each would react to hurricane wind speeds, to make recommendations for different situations. "Our simple simulation of stem breakage potential suggests that stand spacing and tree height can be manipulated to reduce risk, and provides a start for managing forests...Primitive yeast yields secrets of human cholesterol and drug metabolism
... may provide clues to how and why different people react differently to certain drugs. “Understanding the molecular underpinnings of so-called pharmacogenetic variation will have a big impact on the future of medicine,?he says....Common algae helps illustrate mammalian brain electrical circuitry
...to studying how different nerve cells in the brain react to stimuli from the environment, this mouse model is the first to be able to provide real-time mapping of brain circuitry in a living, intact mammal, the researchers said. The light-producing gene inserted into the mice is taken from the water-dwe...Scientists to track impact of Asian dust and pollution on clouds, weather, climate change
...to studying how different nerve cells in the brain react to stimuli from the environment, this mouse model is the first to be able to provide real-time mapping of brain circuitry in a living, intact mammal, the researchers said. The light-producing gene inserted into the mice is taken from the water-dwe...HIV protein enlisted to help kill cancer cells
...are sick, but they keep growing because they don't react to internal signals urging them to die. Now researchers at Washington University School of Medicine in St. Louis have found an efficient way to get a messenger into cancer cells that forces them to respond to death signals. And they did it using one ...Racing neurons control whether we stop or go
...e chance to knock ‘go?out of the race. It needs to react strongly and rapidly after the stop signal is given," Schall said. "If it is successful, the subject stops his or her planned movement. If it is unsuccessful, the subject goes ahead. In individuals with impulse control problems, ‘stop?more often lose...Homing pigeons get their bearings from their beaks
...nts of the magnetic field vector separately. They react to the Earth’s external magnetic field in a very sensitive and specific manner, thus acting as a three-axis magnetometer. The study suggests that the birds sense the magnetic field independent of their motion and posture and thus can identify thei...MU researcher placing eye implants in cats to help humans see
...ip includes several thousand microphotodiodes that react to light and produce small electrical impulses in parts of the retina. "We are really excited about the potential uses for this technology and the potential to create improved vision in some of the millions of people affected worldwide with retina...Genetic pathways to curable and incurable forms of pancreatic cancer identified
...o to cause symptoms. The cells in this cancer also react differently to a key signaling protein, TGFb, which can induce cancer cells to change shape and become more mobile and invasive. It turns out that the cystic pancreatic cancer cells are resistant to these effects of TGFb and these types of cancers ar...Need oxygen? Cells know how to spend and save
..." Semenza says, "so it's vital for them to quickly react to slight changes in oxygen levels." The protein-s...ytochrome coxidase, or COX for short. If electrons react with oxygen before reaching COX, they generate "free radicals" that can damage or destroy cells. The...Detecting poisons in nectar is an odour-ous task for honeybees
...es suggests that honeybees may have the ability to react to toxins, even if they cannot taste them. Rese... eating a toxin. This suggests that honeybees can react to toxins in nectar, but that this ability may mainly be after they have ingested the toxins....