A New Era of Hope for the World's Most Neglected Diseases
...there is sufficient funding, at standard attrition rates these projects would be expected to deliver eight or nine new neglected-disease drugs within the next five years. “The post-2000 renewal of neglected-disease R&D activity is good news for patients with neglected diseases,?writes Moran. There are...Penicillin, amoxicillin: Step aside for strep throat treatment
...t doctors are shocked to learn of the high failure rates of the older medications," said Pichichero, a professor of Microbiology and Immunology. "The treatment paradigm for treating strep sore throats has been changing slowly, and endorsing the use of cephalosporins as a first-line treatment is something ...Looking for the genes that affect a person's level of response to alcohol
...e scientific and clinical community know that high rates of consumption at any age lead to poorer outcomes, both in terms of psychosocial as well as medical functioning. While some individuals might say 'I'm not an alcoholic' or 'I'm not one of those down and out alcoholics,' the truth is that high levels...Do the Europeans turn ill sitting up so late?
...nce decrements, mood disorders, increased accident rates and considerable decrease in the quality of life.Sleep loss may also predispose individuals to conditions such as burn-out and cardiovascular diseases. The EU has granted a 4,4 million Euro funding for this research project from the Marie Curie 6th ...Microarray technology for tailoring breast cancer therapy
...hers gave significantly better(P=0.007) prediction rates than histological grading, tumour stage and age - which are all accepted prognostic markers for breast cancer. The present lack of criteria to help tailor breast cancer treatment to individual patients indicates a need to develop new techniques for ...Leading lampreys to slaughter: Pheromone for scourge of Great Lakes identified
...s has been shown to work," said Sorensen. "Capture rates are up six-fold." Most lamprey traps have been simple, rather ineffective devices, but now the attractants have opened up many new possibilities for attracting lampreys safely, easily and inexpensively into streams, where they might be captured. In t...Jefferson scientists identify gene defect leading to abnormal skin development and cancer
...s has been shown to work," said Sorensen. "Capture rates are up six-fold." Most lamprey traps have been simple, rather ineffective devices, but now the attractants have opened up many new possibilities for attracting lampreys safely, easily and inexpensively into streams, where they might be captured. In t...Some good news for the world's poor
...portunities as well as the upward pressure on wage rates in the labor market. Explaining the large difference in impact between the 15,000 lifted out of poverty in India and the 800 in China, Dr. Fan said this was because China had already achieved rapid and very large reductions in poverty before 1999. "...Johns Hopkins flu expert calls for mandatory vaccination of health care workers
...cisely link seasonal hospital absenteeism and high rates of non-vaccination, she notes. "We need to close ...mpaigns can be effective at increasing vaccination rates among health care workers by as much as 60 percent. And to the surprise of those conducting these s...Amazon trees much older than assumed, raising questions on global climate impact of region
...zon, where we found the slowest growing trees, the rates of carbon uptake are roughly half what is predicte... shade under the canopy of large trees. The growth rates they measured for Central Amazon trees are among the slowest in any forest on Earth. These results, ...New study pinpoints epicenters of Earth's imminent extinctions
...rocess, the authors note that current human-caused rates of species loss are 100-1,000 times greater than natural rates. In recent history, most species extinctions have occurred on isolated islands following the introduction of invasive predators such as cats and rats. This study shows that the extinction...Pretreating rogue cancer cells with aspirin cripples their resistance to targeted therapy
...rocess, the authors note that current human-caused rates of species loss are 100-1,000 times greater than natural rates. In recent history, most species extinctions have occurred on isolated islands following the introduction of invasive predators such as cats and rats. This study shows that the extinction...Scientists fetch useful information from dog genome publications
...and cytosine DNA bases and appear to suffer higher rates of mutation." SINEs of genetic diversity Another study appearing in the dog genome section of Genome Research highlights an important source of canine genomic variation: SINEs, or short interspersed elements. SINEs are abundant mobile DNA e......and cytosine DNA bases and appear to suffer higher rates of mutation." SINEs of genetic diversity Another study appearing in the dog genome section of Genome Research highlights an important source of canine genomic variation: SINEs, or short interspersed elements. SINEs are abundant mobile DNA e...Antibacterial coatings cut infection rates
...ical devices such as catheters could cut infection rates following surgery and significantly reduce health care costs and improve quality of life for patients, researchers at the University of South Australia have found. A significant number of hip and knee implants are prone to infection after surgery an...Birth defects: 8 million annually worldwide
...ren occur, the report finds. Both high prevalence rates and larger numbers of births contribute to the dif...ort notes major demographic reasons for the higher rates of birth defects in poorer countries, including more women of advanced age having children and a gre...MRSA use amoeba to spread, new research shows
...se 5 per cent between 2003 and 2004, and mortality rates increased 15-fold between 1993 and 2002. ...Combination therapy improves AIDS-related lymphoma outcome
...d chemotherapy significantly improves the survival rates of HIV-positive men and women treated for lymphoma...stigators found combined therapy improved survival rates for patients with ARL and standard level of risk to rates comparable to those in non-HIV patients wi...Parents need to be educated about HPV vaccinations for daughters
... infection despite the vaccination. Falling death rates have also been due to improved forms of treatment for advanced disease, principally in the form of concomitant chemotherapy and radiotherapy." Professor Kitchener concluded: "HPV vaccines provide hope for major international programmes of primary pr...Hormonal male contraception reversible after few months for all men
...onths. Various factors were associated with higher rates of recovery including older age, Asian origin, shorter treatment duration, and higher sperm concentrations at baseline. Although these factors modulated the speed of recovery, spermatogenesis recovered to levels compatible with fertility in all men. ...