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Tag: "quest" at biology news

MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks

...d Dr. Brent. "It is a critical step forward in our quest toprovide an accurate simulation of intracellular biochemical networks.""I've designed Moleculizer to be intuitive for biologists," said Dr.Larry Lok, a mathematician who conceived and programmed Moleculizer."Its parallel simplifications in simulatio...

Scientists identify molecule that regulates well-known tumor suppressor

...t abnormally high levels of PKB/Akt activity. In a quest to determine what molecules regulate normal PTEN, Dr. Tak W. Mak from the Ontario Cancer Institute and the University of Toronto and colleagues used a genetic screening method in fruit flies and identified the molecule DJ-1 as a PTEN suppressor. In ...

Study: 'homemade' gene expression technology unreliable

...enomes of humans and other animal species in their quest to find cures for a variety of diseases. "Human genome mapping has made the production of these microarrays possible," Spencer said. "Our interest is in how environmental factors ?drugs, pollutants, workplace substances, natural toxins, food chemica...

15-year hunt finds cause of pseudothalidomide syndrome

..., in 1995, two Colombian geneticists started their quest to fully understand Roberts syndrome. Without their push, the gene for Roberts might still be unknown. Colombian Hugo Vega had noticed an unusual number of patients with Roberts syndrome in the clinic at the University of Bogotá. Fairly quickly, he ...

Newly discovered protein an important tool for sleeping sickness research

...d functions, is a significant breakthrough in this quest because Sabatini and his colleagues were able to demonstrate that the protein is the key regulator of base J synthesis. This will provide the scientists a new tool to elucidate the biological function of this unique modified DNA base in the regulatio...

Breakthrough System for Understanding Ocean Plant Life Announced

...d functions, is a significant breakthrough in this quest because Sabatini and his colleagues were able to demonstrate that the protein is the key regulator of base J synthesis. This will provide the scientists a new tool to elucidate the biological function of this unique modified DNA base in the regulatio...

ORNL, UC Berkeley unravel real-world clues to Earth's mysteries

...ornia could be a gold mine to researchers in their quest to understand the complex biological relationships and how these inner workings might apply on a grander scale. In a paper to appear today on Science Online, researchers from the Department of Energy's Oak Ridge National Laboratory and the Universit...

Going To Extremes To Improve Human Health

...extreme range of environmental conditions in their quest to test and understand the human body's response to everyday stresses. The instrument, called an environmental chamber, is a 12-foot-square room capable of simulating altitude up to 18,000 feet, holding temperature constant at a set point between 14...

Snapin: A protein with therapy potential for autism

... correlate with specific disorders and Firestein's quest is to discover how these dissimilar patterns come about and why. A new paper by Firestein and her colleagues at Rutgers, The State University of New Jersey, examines the role of the protein snapin in nerve branch, or dendrite, patterning and its pot...

Rodent social behavior encoded in junk DNA

...very is the latest in a two decades-old scientific quest for the neural basis of familial behavior begun at the NIMH Intramural Research Program in the mid l980s by now NIMH director Thomas Insel, M.D. By l993, his team had discovered that the distribution of brain receptors that bind to the hormone vasopr...

Team of international scientists departs today to discover the unknown in China's Himalayan region

In the quest to discover new species, a team of international scientists leaves today on a month-long expedition to explore the undiscovered treasures in the Mountains of Southwest China, an extension of the great Himalayan mountain range. "Expedition Everest: ...

Columbia scientists develop cancer terminator viruses

Results advance quest for viral-based therapies for cancer Researchers at Columbia University Medical Center continue to make strides in their work to develop the next generation of effective viral-based therapies for cancer. Two papers about promising research with gen...

Scientists map one of biology's critical light-sensing structures

...r graduate student Jeremiah Wagner, caps a 30-year quest by biologists to drill down to the inner workings of how plants, fungi and bacteria use light to guide their development. It will likely spur a rush by scientists to capitalize on the new knowledge and may one day lead to such things as plants whose...

Recreating 'Flowers for Algernon' with a happy ending

...long-term use. "It became something of a Quixotic quest -- an impossible dream," Silva admitted. "We thought, 'Wouldn't it be nice to find a drug that is already FDA-approved, safe for lifetime use and could be tested in mice and humans with NF1?' Fortunately, our optimism was rewarded." It took a medi...

Seal rookeries could provide a reliable food source for endangered California condors, study finds

...berlain and his colleagues embarked on a worldwide quest for feather and bone samples that would reveal the body chemistry of condors through the ages. "This work was fun," Chamberlain recalls. "First we got modern feathers from the Ventana Wildlife Society in Big Sur, Calif., and other groups involved in ...

ASU researchers 'wire' DNA to identify mutations

...ifferences among the populace will aid the ongoing quest to understand and prevent disease. "There is a high demand to track mutations for cancer research or future applications in personalized medicine," said Zhang, an associate research professor of the Center for Single Molecule Biophysics in the Biod...

Researchers reverse juvenile diabetes in animal model

... cure for diabetes -- finding a cure is a personal quest for him. As an international leader in the field of immunogenetics, Dr. Trucco has pioneered numerous important studies and also maintains a federally funded national bone marrow HLA typing center within his lab.With this funding, Dr. Trucco and his ...

Mining for gems in the fungal genome

... developed a new method that may speed the ongoing quest for medically useful compounds in fungi. By manipulating a single fungal protein, the team, led by professor of plant pathology and medical microbiology Nancy Keller, pinpointed the genes responsible for creating dozens of secondary metabolites, a...

New RNAi tools enable systematic studies of gene function

...f the Broad Institute and a senior author. "In the quest to develop comprehensive tools for gene discovery in mice and humans, this technology will be a key piece in the puzzle." To evaluate the RNAi library's performance, the scientists sampled a subset that targets approximately 1,000 human genes. They ...

St. Jude projects 90 percent cure rate for ALL

...0 percent is an important step toward our ultimate quest of curing all children with this disease." ...

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