Common cancer gene sends death order to tiny killer
... colleagues in Hopkins's department of medicine to put miR-34a into colon cancer cells. Doing this killed cells that contained p53, but fewer were killed in cells lacking p53, further suggesting that this microRNA gets its kill orders from p53. When researchers examined pancreatic cancer cells known t...The insect vector always bites twice
...ected, vectors or non-vectors, were separated then put into contact with the serum of individual subjects, infected or uninfected, exposed to bites. Comparison of salivary protein immunogenic profiles obtained showed that they differ depending on the infection status of the subjects (exposed uninfected/i...Studies to find better ways to preserve human eggs, ovarian tissue under way
...uid nitrogen takes it to minus 196 degrees “You put it in a control-rate freezer that takes down the t...tcomes,” Dr. Song says. Later, researchers will put ovarian tissue preserved both ways into mice to see if it survives and starts making proper connecti...In mice, drug protects against diabetes and atherosclerosis
...he drug or an inert substance. One set of mice was put on a high-fat "western" diet at five weeks of age; half received the inhibitor drug. A second group of animals ate the western diet for eight weeks, at which time they developed severe atherosclerosis. Then they were started on the drug to determine ...Brightening prospects of using fluorescent nanotubes in medical applications
...lve. The result is a dark liquid that is routinely put into an ultracentrifuge that subjects them to forc...om the centrifuge, let it set for a while and then put it back in the ultracentrifuge for another 12 hours, the liquid separates into a number of distinct ...Breakthrough developments in rheumatoid arthritis reported
...eases like rheumatoid arthritis, PTPN22 appears to put people at higher risk of a wayward T-cell response. The group has since gone on to use modern genetic methods to search for single nucleotide polymorphisms, or SNPs, to identify players that have fallen under the radar of older methods. The grou...Runners -- Let thirst be your guide
...rts drinks, when exercising, a practice that could put some individuals engaging in prolonged types of endurance exercise at risk of potentially lethal water intoxication, say international experts who study disorders of water metabolism. Such exercise includes marathons, triathlons, and long distance cy...3-D ultrasound scanner provides in-depth view of the brain
...e is a commercial 2-D niche now, we are working to put a 3-D tool in there," Smith said. ...Putting feelings into words produces therapeutic effects in the brain
...e reduction in the amygdala response. “When you put feelings into words, you’re activating this prefro...u’re driving when you see a yellow light, when you put feelings into words, you seem to be hitting the brakes on your emotional responses.” As a result,...St. Jude study shows genes play an unexpected role in their own activation
...ing it and which signaling molecule caused cAMP to put CREB to work,” Brindle said. “It is another clue to how CREB might activate the genes for enzymes that make glucose in the liver, while activating different genes in the brain that are key to learning and forming memories.” A long-term implication...'Smart' mice teach scientists about learning process, brain disorders
...said. "It’s been shown that it can be done, but we put the system together and actually applied it." Normally, Cdk5 works with another enzyme to break up a molecule called NR2B, which is found in nerve-cell membranes and stimulates the cell to fire when a nerve-cell-signaling molecule, or neurotransmi...'Personality-gene' makes songbirds curious
... towards each of two unknown objects that had been put in its cage. One such novel object was a pink panther (see figure 2). The results from the group of selected birds were confirmed with data from free-living, unselected great tits. In the forest-living birds, the scientists also found a significa...Technique monitors thousands of molecules simultaneously
...l to form a carbonyl and then used the carbonyl to put a dye down. They placed a green dye at alternating..., and then used the alternate set of electrodes to put down a red dye. The result was a red and green chip, Washington University's colors. This, Moeller s...An ancient bathtub ring of mammoth fossils
...ific Northwest National Laboratory geologists have put out a call for teeth tusks, femurs and any and all other parts of extinct mammoths left by massive Ice Age floods in southeastern Washington. The fossils, in some cases whole skeletons of Mammathus columbi, the Columbian mammoth, were deposited in t...Premature births may be linked to seasonal levels of pesticides and nitrates in surface water
...initiatives of our time. To recognize that what we put into our environment has potential pandemic effects on pregnancy outcome and possibly on child development is a momentous observation, which hopefully will help transform the way humanity cares for its world," said James Lemons, M.D., Hugh McK. Lando...Molecule that destroys bone also protects it, new research shows
...ing indicates that inhibiting IL-17 too much could put people taking such a drug at risk for opportunistic infections such as periodontal disease and tuberculosis, she noted. "Developing knowledge about the molecules that contribute to host defense versus pathology is very important for gaining a fun...World's leading scientists announce creation of 'Encyclopedia of Life'
...id at TED. "What excites me is that since I first put forward this idea, science has advanced, technology has moved forward. Today, the practicalities of making this encyclopedia real are within reach as never before." Ultimately, the Encyclopedia of Life will provide users the opportunity to person...Female-led infanticide in wild chimpanzees
... from demographic shifts that alter sex ratios and put increased pressure on females competing for foraging areas. In their report, the authors note that the Sonso community had experienced a significant population increase in the ten years prior to the infanticide observations (42 individuals in 1996 to...Chemical maps hint at drug's effects on schizophrenia
... in metabolic side effects. "Clearly we need to put forth a major effort to link the changes in the blood to what happens in the brain," Kaddurah-Daouk said. "If we can apply these findings to the mysteries occurring in the brain, then perhaps we can finally unlock the secrets of these devastating dis...Study warns deep-sea mining may pose serious threat to fragile marine ecosystems
...tion on the Law of the Sea (UNCLOS) have currently put those projects on hold. In particular, says Halfar, restrictions by the International Seabed Authority—which overseas environmental protection and demands that profits from mining in international waters be shared with developing nations—redirected p...