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Tag: "pumps" at biology news

Purdue proves concept of using nano-materials for drug discovery

...mor chemotherapy drugs. These proteins act as tiny pumps that quickly remove chemotherapy drugs from tumor cells, making the treatment less effective. Cancer cells exposed to chemotherapy drugs produce a disproportionately large number of the pumps, causing the cells to become progressively more resistant ...

Development of portable infectious disease detector

...y. However, puttingmicroscopic arrays of channels, pumps and valves to move around minuteamounts of liquid on silicon chips proved to be considerably moredifficult than most of the inventors had expected and the products thatthese companies have created thus far have been too expensive for thepoint-of-care...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

...ed.?/p> So UF scientists developed a system of pumps they can use to expose bacteria to changing concentrations of an antibiotic, mimicking the concentration profile present in a patient at the actual site of an infection. They then measure how quickly the bacteria are killed or see if they regrow, and...

Alcohol consumption disrupts breastfeeding hormones

...ming the beverages, the women used electric breast pumps to stimulate lactation. Blood samples taken throughout the procedure were analyzed for oxytocin and prolactin, the two key hormones that control lactation. Alcohol disrupted release of both hormones during lactation: oxytocin levels decreased an ave...

'Sinkers' provide missing piece in deep-sea puzzle

...es that the animals eats. The larvacean constantly pumps water through both filters, which typically become clogged after about 24 hours of use. At this point the larvacean abandons its house and swims off to create a new one. The cast-off larvacean house eventually deflates like a punctured balloon and si...

Implantable pumps extend lives of patients too sick for transplant

...rt's left ventricle ?the chamber of the heart that pumps blood throughout the body ?is too weak to pump eno...fferent trials testing different device models and pumps designs. ...

Drug resistance may travel same path as quorum sensing

...ces. "We believe that the drugs exported by these pumps may actually be similar in structure to molecules ..., and when it does, it increases the number of the pumps to try to send out the molecules. The doctor is trying to kill the bacterial cells with drugs, but t...

Genes affecting blood pressure change as children become adults

...s ?such as heart rate and how much blood the heart pumps with each beat ?near the beginning and end of the biologically tumultuous times. Researchers left much-discussed obesity out of this equation, focusing instead on genes and environmental factors directly influencing blood pressure and hemodynamics. ...

Use of amino acid supplement following a heart attack provides no benefit, may be harmful

... of how much blood the left ventricle of the heart pumps out with each contraction). The randomized, double-blind, placebo-controlled trial included 153 STEMI patients; 77 were 60 years or older. Participants were enrolled from February 2002 to June 2004. Patients were randomly assigned to receive L-argi...

Little known DNA repair enzyme may be a tumor suppressor gene

... of how much blood the left ventricle of the heart pumps out with each contraction). The randomized, double-blind, placebo-controlled trial included 153 STEMI patients; 77 were 60 years or older. Participants were enrolled from February 2002 to June 2004. Patients were randomly assigned to receive L-argi...

An elephant tail

... of how much blood the left ventricle of the heart pumps out with each contraction). The randomized, double-blind, placebo-controlled trial included 153 STEMI patients; 77 were 60 years or older. Participants were enrolled from February 2002 to June 2004. Patients were randomly assigned to receive L-argi...

U of MN uses robotic surgery techniques in cardiac cell therapy research

... the left ventricle, the chamber of the heart that pumps blood into the aorta, the main artery through which oxygen-rich blood flows from the heart to the body. Taylor said more research needs to be done to determine which types of cells are most beneficial to infuse into damaged hearts, as well as if the...

UF scientists test improved gene therapy method for hereditary heart conditions

...AAV-9 to contain copies of a therapeutic gene that pumps out an enzyme missing in a mouse model for Pompe disease. The ailment is caused by a single defective gene that fails to produce adequate levels of an enzyme that normally breaks down the carbohydrate glycogen, used to store energy. The disease cause...

Methane-belching bugs inspire a new theory of the origin of life on Earth

... indirectly, from yet another protein machine that pumps an osmotic imbalance across the membrane. "It's difficult to imagine that something so complex could have emerged all at once," Ferry says, as the chemoautotrophic theory requires. The acetate-producing species appears to be the direct descendant of...

UNH researcher restoring oyster reefs to Great Bay

...y could be significant: Each oyster, says Grizzle, pumps 20 or so gallons of water each day through them, retaining particles as small as a virus. "They're marvelous filters," he says. Further, he notes that oyster reefs, much like seagrass beds or coral reefs, support a variety of marine life. "Oyster r...

Five new technologies that promise to transform medicine

...evels. And further into the future are links smart pumps that, when signalled, instantly deliver the correct medication. Another prediction is the use of miniature telescopes that restore vision for patients with degenerative eye disease. The telescopes are powered by sunlight passing through the pupils...

New biochip helps study living cells, may speed drug development

... than patch-clamping, he said. Ion channels and pumps establish a difference in electrical potential across a cell's membrane, which cells use to create energy and transfer electrical signals. By quickly allowing ions in and out, they are useful for rapid cellular changes, the kind which occur in muscle...

Cigarette smoking impedes tendon-to-bone healing

...f surgery. The researchers implanted tiny, osmotic pumps under the skin of the rats, and those pumps delivered either nicotine or an inactive saline solution. Saline pumps were implanted to ensure that...

PNAS study reveals why organs fail following massive trauma

...rough adaptive immune system. This second system pumps out an endless variety of immune cells on the hope that one or more will be the right shape to link up with, and become activated by, any invader encountered. When one of those immune cells, called lymphocytes, recognizes a bacterium or virus present...

MIT designs portable 'lab on a chip'

...ric field across the chip. Current electro-osmotic pumps require more than 100 volts of electricity, but th... Thorsen's group is working toward integrating the pumps into a portable blood analysis device, which soldiers could carry onto the battlefield. If exposure ...

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