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Tag: "published" at biology news

New drug shows promise as powerful anticancer agent

Research published in the March issue of the journal Cancer Cell describes a small molecule inhibitor of polo-like kinase1 (Plk1) that could lead to a new avenue for targeted cancer therapy. The compound, ON01910, is a potent inhibitor of human tumors in a mouse model ...

Alzheimer's cognitive decline slowed

...abolic activity in the brain, according to a study published in the April 24, 2005 online issue of the journal Nature Medicine by researchers at the University of California, San Diego (UCSD) School of Medicine. PET scans demonstrated an increase in the brain's use of glucose, an indication of increased brain...

Scientists identify molecule that regulates well-known tumor suppressor

...e well-known tumor suppressor, PTEN. The research, published in the March issue of Cancer Cell, has important implications for determining the prognosis of some human cancers, and may prove to be a suitable target for cancer therapy. The phosphatidylinositol 3' kinase signaling pathway regulates cell growth a...

Birds brains reveal source of songs

...Govern Institute about his recent study, which was published online in advance of the May issue of the free access journal, Public Library of Science Biology. "We've known there are several brain areas involved: a motor circuit for producing the song, and a learning circuit, called the AFP (for anterior forebr...

Survey finds silver contamination in North Pacific waters

...try, Geophysics, Geosystems, an electronic journal published by the American Geophysical Union and the Geochemical Society. Ranville found silver concentrations as high as 1.2 parts per trillion in samples of North Pacific surface waters taken during the cruise. This is about 50 times higher than baseline lev...

Buying Time Through Hibernation on Demand

...estigator Mark Roth, Ph.D., whose findings will be published in the April 22 issue of Science. "We think this ...ddition to mice, Roth and colleagues in previously published work have demonstrated the ability to metabolically arrest ?and subsequently re-animate ?such model ...

Anti cancer virotherapy well tolerated in first human administration, research finds

...in adult humans. Previously the Shafren group has published research on CVA21 that showed success in specifically targeting and killing melanoma cells in mice . The virotherapy technique involves the specific targeting and killing of cancer cells through the introduction into the body of the appropriate vira...

U-M team recovers ancient whale in Egyptian desert

...estigator Mark Roth, Ph.D., whose findings will be published in the April 22 issue of Science. "We think this ...ddition to mice, Roth and colleagues in previously published work have demonstrated the ability to metabolically arrest ?and subsequently re-animate ?such model ...

Love's all in the brain: fMRI study shows strong, lateralized reward, not sex, drive

... the July issue of the Journal of Neurophysiology, published by the American Physiological Society. The researc... the July issue of the Journal of Neurophysiology, published by the American Physiological Society. ...

Navigating an integrated yeast network

...ents of a cell influence one another. New research published in the Open Access journal Journal of Biology shows that such maps can also reveal cryptic interactions and enable accurate predictions about interactions that haven't been observed experimentally. A living cell contains thousands of proteins, genes...

Researchers uncover sequence of major rice pathogen

...esearch paper that describes the M. grisea genome, published in the April 21 issue of the journal Nature. It is estimated that rice blast, the leading cause of rice loss, is responsible each year for killing enough rice to feed 60 million people worldwide. In the Nature paper, Dean and his co-authors shed so...

miRNA profiling

To be published in the June 1 issue of G&D, Dr. Thomas Tuschl and colleagues describe the most comprehensive profile to date of microRNA (miRNA) expression during zebrafish development. The authors cloned 154 distinct miRNAs (10 of which are completely novel) in...

Researchers make gains in understanding antibiotic resistance

... professor of chemistry at Yale, the research team published its findings in the April 22, 2005, issue of the j... it." Steitz cited, for example, recent statistics published in the journal Nature, stating that hospitals in the United States see some two million cases of ant...

Harmful chemicals may reprogram gene response to estrogen

... for the two-year study. The study results will be published in the May 2005 issue of the Proceedings of the National Academy of Sciences. The discovery is important because it changes conventional thinking about the way in which genetic predisposition and things in the environment interact to increase diseas...

Silence the gene, save the cell: RNA interference as promising therapy for ALS

... fatal motor neuron disease. Their results will be published in the April issue of Nature Medicine, and in the journal's advanced online publication March 13. In addition to silencing the mutated gene that causes ALS, the EPFL researchers were able to simultaneously deliver a normal version of the gene to mot...

Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis

...gator at St. Jude Children's Research Hospital, is published in the February 18 issue of Science. Mcl-1 blocks the biochemical cascade of reactions that trigger apoptosis ("cell suicide") of HSCs, according to Joseph Opferman, Ph.D., assistant member of St. Jude Biochemistry. Expression of Mcl-1 thus ensures ...

Revolutionary nanotechnology illuminates brain cells at work

...zheimer's and Parkinson's disease. The research is published in the May 30-June 3 on-line early edition of the Proceedings of the National Academy of Sciences. "The fluorescent imaging technique allows us to see living cells do their jobs live and in color," explained Sakiko Okumoto, lead author of the study ...

Researchers report new pro-inflammatory role for anti-inflammatory enzyme

...called inducible nitric oxide synthase. In a study published in the Journal of Biological Chemistry, scientists report that the predominantly anti-inflammatory enzyme, endothelial nitric oxide synthase, is also involved in nitric oxide production in response to infection. This discovery may eventually provide ...

Two are better than one

...with mixtures of customized antibodies. In a study published recently in the Proceedings of the National Academy of Sciences (USA), a team of Weizmann Institute scientists have demonstrated how the right combination might form a web that destroys the cancer cell's communication network, ultimately demobilizing...

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

...ptoms of the disease develop, according to a study published in the May 19, 2005, issue of the New England Jour...ildren with Hurler Syndrome, results of which were published in the May 6, 2004, issue of the New England Journal of Medicine. In that study, Kurtzberg's team de...

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