Elusive HIV shape change revealed; Key clue to how virus infects cells
...S virus to enter and infect cells. Their findings, published in the Feb. 24 issue of the journal Nature, offer clues that will help guide vaccine and treatment approaches. Researchers led by Howard Hughes Medical Institute Investigator Stephen Harrison, PhD, and Bing Chen, PhD, focused on the gp120 protein, p...Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
...amoeba. It is also the first genome sequence to be published from this class of amitochondrial human pathogens. The analysis reveals the degradation of the E. histolytica genome in its transition from a free-living organism into a parasite of the human gut. At the same time, scientists also cataloged the rete...Antarctic ice shelf retreats happened before
...rctic ice shelves is not new according to research published this week (24 Feb) in the journal Geology by scientists from Universities of Durham, Edinburgh and British Antarctic Survey (BAS). A study of George VI Ice Shelf on the Antarctic Peninsula is the first to show that this currently 'healthy' ice shelf...Anti-bacterial additive widespread in U.S. waterways
...more easilydetectable.Using an empirical model and published data on the environmentaloccurrence of triclosan, the researchers predicted triclocarbanconcentrations for 85 U.S. streams. The study results suggest that theantimicrobial contaminant is present in 60 percent of the U.S. waterresources investigated, ...Plants, animals share molecular growth mechanisms
... of cells in the plant." Results of the study are published in the February issue of the journal The Plant Cell. "Perhaps by learning about this pathway for actin filament formation, we can engineer plant cells to grow in different ways or alter how cells respond to external stimuli so they can defend themse...Researchers Uncover Key Step In Manufacture of Memory Protein
... Section on Cellular Neurobiology. The researchers published their work in the January 20 issue of Neuron. Specifically, the researchers discovered that the enzyme carboxypeptidase E, (CPE) is needed to deliver the early, or inactive, form of BDNF ?proBDNF ?to a special compartment in the neuron (nerve cell.)...Plants respond similarly to signals from friends, enemies
...to burrow in and harm the plant. In a new finding published in Proceedings of the National Academy of Sciences, researchers at North Carolina State University have found that the two strangers communicate with the plant in very similar ways. The plant's responses to both friend and foe are also remarkably sim...Research advances quest for HIV-1 vaccine
...istic for HIV discovered thus far. The research is published in the February issue of Immunity. Vaccination has been a successful strategy for protecting humans from many potentially harmful viruses. However, designing a suitable vaccine for HIV-1 has been a highly challenging and thus far unsuccessful endeav...The secret to longevity in tubeworms
... for this long has been a mystery. In a paper just published in the premier open-access online journal PLoS Biology, Erik Cordes and colleagues now provide a solution: by releasing its waste sulfate not up into the ocean but down into the sediments, L. luymesi stimulates the growth of sulfide-producing microbe...Male circumcision reduces risk of HIV transmission from women to men
...cquiring HIV than do circumcised men.In the study, published in the Feb. 15 issue of The Journal ofInfectious D...culated using a statistical model thatincorporated published data to estimate the rates of HIV infectionamong the three types of sexual partners.For the men in t...Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering
...thepast ten years more than 3,000 papers have been published usingGeneChip technology. For more information, please visitwww.Affymetrix.com....A much-needed shot in the arm for HIV vaccine development
...IDS Vaccine Enterprise'sscientific strategic plan, published online in the freely available,open-access global health journal PLoS Medicine.The Global HIV/AIDS Vaccine Enterprise is an international alliance ofindependent agencies and organizations conducting or supporting HIVvaccine research. In June 2004, th...New Technique for Tracking Gene Regulators
...chool of Medicine, and Stony BrookUniversity, have published the first results using their technique inthe December 29, 2004 issue of Cell, where they describe thehuman-genome binding sites of a regulator protein known as CREB.“Though scientists have now decoded almost all of the entire humangenome ?the series...Bound for destruction: Ubiquitination protects against improper Notch signaling
...d fromdigestion by that protease. Now, in a report published in the December29 issue of Current Biology, Shigeo Hayashi (Group Director, Laboratoryfor Morphogenetic Signaling) and colleagues at the RIKEN Center forDevelopmental Biology (Kobe, Japan) have identified the means by whichunstimulated cells protect ...Combination therapy boosts effectiveness of telomere-directed cancer cell death
...imes worth it, as we can see .A new research study published in the January issue of Cancer Cellprovides exciting new information about how to boost the effectivenessof a promising cancer treatment that targets telomeres in an attempt tointerfere with the ability of a cancer cell to continuously divide. Telom...GATA: a graphic alignment tool for comparative sequence analysis
...imes worth it, as we can see .A new research study published in the January issue of Cancer Cellprovides exciting new information about how to boost the effectivenessof a promising cancer treatment that targets telomeres in an attempt tointerfere with the ability of a cancer cell to continuously divide. Telom...Whole genome fine map of rice completed
...uence of the Chinese hybrid rice genome, which was published in the Journal Science in 2002, CAS researchers ha...hed the fine map of the rice genome. In an article published by the recent issue of PLoS Biology (Vol.3 Issue 2, 2005), scientists led by the Beijing Institute o...Imaging Lymph Nodes with Nanoparticles
...abnormal pattern on MRI scans. Ina previous paper published in the New England Journal of Medicine,Ralph Weiss...d in patients with prostate cancer. Now, in apaper published in this month's PLoS Medicine, they have gone furtherby extending the analysis to patients with diff......f human neurological disease,according to research published in the Dec. 16 issue of Nature. Dr.Adela Ben-Yakar, an assistant professor of mechanical engineering atThe University of Texas at Austin, led the development of thetechnique. It acts like a pair of tiny “nano-scissors,?able to cut,for example, nano-...