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World's leading scientists announce creation of 'Encyclopedia of Life'

...fe efforts, including the scanning of key research publications and data, have been underway since January 2006, work has accelerated due to the support provided by the John D. and Catherine T. MacArthur Foundation and the recent discussion of the Encyclopedia of Life by renowned biologist Edward O. Wilson at the...

DOE JGI sets 'gold standard' for metagenomic data analysis

...pse of the identities of multiple genomes. All the publications to date have made the assumption that these tools will work as efficiently for metagenomes, "but we really didn't know." Nikos Kyrpides, DOE JGI Genome Biology Program Head, said that, to evaluate the magnitude of this problem and identify the inh...

Lighting up life: Cold Spring Harbor Protocols presents tips for creating glowing plants

... cells for studies in cell division. Both of these publications join a growing library of high-quality methods from Cold Spring Harbor Protocols that span a broad spectrum of topics essential to researchers across many disciplines. ...

Erectile dysfunction in diabetes is due to selective defect in the brain

...ive Physiology, one of 11 peer-reviewed scientific publications issued monthly by The American Physiological Society (APS) ( www.The-APS.org ). Background Sexual dysfunction is a well-recognized consequence of diabetes mellitus in men. Erectile dysfunction, retrograde ejaculation and the loss of seminal ...

Getting to the heart of the heart

...yonic development. "There have been a number of publications about stem-like cells in the heart, but these are the first studies to identify such cells during embryonic development, and to show that they give rise to different cell types," says Orkin, who is the David G. Nathan Professor of Pediatrics at Harva...

Genetic 'roadmap' charts links between drugs and human disease

... the September 29 issue of Science and in separate publications in the September 28 immediate early edition of Cancer Cell. The three papers show the map's ability to accurately predict the molecular actions of novel therapeutic compounds and to suggest ways that existing drugs can be newly applied to treat disea...

Scientists use gene signatures to match cancer and other diseases with potentially effective drugs

...r: That set of genes makes up the signature. The publications describe how the Connectivity Map, which in its initial edition contained links to 164 different drugs and other chemical compounds, was used to obtain information on treatments for obesity, Alzheimer's disease, and cancer, and to suggest new therapi...

Virtual realities against pain

...y more activities. In this study, peer-reviewed publications on ADTs and pain have been reviewed to determine the clinical effectiveness and importance of using these techniques as analgesic. The results suggest that the ADTs can significantly reduce the pain associated with medical treatment. The use of analg...

BioMed Central launches Biology Direct

... online at www.biology-direct.com , launches with publications in the fields of Systems Biology, Computational Biology, and Evolutionary Biology, with an Immunology section to follow soon. Biology Direct considers original research articles, hypotheses, and reviews and will eventually cover the full spectrum of ...

Blood flow in brain takes a twist, affecting views of Alzheimer's

...ergaard, M.D., Ph.D., who has produced a string of publications fingering astrocytes in diseases like epilepsy and spinal cord injury. "In a disease like Alzheimer's, for instance, perhaps it's the astrocytes themselves that are damaged first," she said. "It may be that for whatever reason, astrocytes are not do...

High-resolution light microscope reveals the fundamental mechanisms of nerve communication

...y.The STED microscope used to obtain data for both publications is able to attain a resolution of 50-70 nm; the original fluorescent spot, roughly 200 nm in diameter, is reduced in surface area within the imaging plane by roughly an order of magnitude using the STED technique. This resolution was sufficient for ...

Free access to a digital library for developing countries

...r's Environmental Online Library covers a range of publications in topics spanning the uncharted depths of the oceans to the outer reaches of our atmosphere. Springer, one of the founding publishers of OARE, has also made available works on environmental policy ?identifying how human behavior can be modified in t...

Fitting in: Newly evolved genes adopt a variety of strategies to remain in the gene pool

... the genome. "Our results contradict other recent publications that have focused on a single selective pressure as the basis for the retention of gene duplicates," explains Dr. Uwe Sauer, principal investigator on the project and Professor at the Institute of Molecular Systems Biology at the Swiss Federal Instit...

The shape of things to come: Morphology database going global

...ic name, common name, who found it and where, what publications it has been in and related species. Any and all relevant information we put in MorphBank." In the future, it may be possible to take a photo of a plant or an animal, send the image to the database and get back a reliable species identification, Gait...

Give thanks for the cranberry, say dental researchers

...es cranberry juice. "There is a massive number of publications about the effect of cranberries on urinary tract infections," said Koo, "but there are only few studies on the dental side." The cranberry research will be published in the January 2006 issue of Caries Research. Other authors include dentist Patrici...

New law for resolution allows unprecedented sharpness in fluorescence microscopy

... a square root term [1,2]: In one of their latest publications [2], the Göttingen-based research team verifies this new law with their experiments. They show that even with conventional objectives and focused light, resolutions of 16 nm are feasible. Therefore for the first time ever, it has been demonstrated ex...

Columbia scientists develop cancer terminator viruses

... Administration and available for patients. These publications are a continuation of research published in the Jan. 25, 2005 issue of PNAS, where the same research team, also led by Dr. Fisher, incorporated gene therapy into a specially designed non-replicating virus to overcome one of the major hurdles of gene ...

Hopkins scientists uncover 'tags' that force proteins to cell surface

...findings, described in the Sept. 11 advance online publications of Nature Cell Biology, might revolutionize efforts in drug and vaccine development, says the Hopkins team. "A typical step in drug development is to get cells in a dish to express the protein you want to target with drugs, and then to test thousand...

CoPub Mapper: mining MEDLINE based on search term co-publication

...to identify biological similarities between genes, publications from MEDLINE were identified in which pairs of gene names and combinations of gene name with specific keywords were co-mentioned. MEDLINE search strings for 15,621 known genes and 3,731 keywords were generated and validated. PubMed IDs were retrieve...

New Estimates For The Causes Of Child Deaths Worldwide

...h Organisation (WHO), analysed available data from publications and ongoing studies in 2000 to 2003 to obtain new estimates for mortality by cause in children younger than age 5 years. They found the four communicable disease categories account more than half (54%) of all child deaths. Infection of the blood or p...

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(Date:8/21/2014)... in the journal Carcinogenesis by researchers at ... the protein adenomatous polyposis coli (APC) in suppressing colorectal ... the U.S. , Lead author Kristi Neufeld, associate professor ... the Cancer Biology program at the KU Cancer Center, ... to understand the various activities of APC, a protein ...
(Date:8/21/2014)... A team of researchers at Louisiana ... for using affordable, consumer-grade 3D printers and ... can contain antibacterial and chemotherapeutic compounds for ... of doctoral students and research faculty from ... programs collaborated to create filament extruders that ...
(Date:8/21/2014)... Carolina State University have developed a novel and versatile ... applications for creating new materials as well as for ... technique allows us to model much larger and more ... quickly," says Nan Li, lead author of a paper ... State,s Department of Materials Science and Engineering. "This is ...
Breaking Biology News(10 mins):Research offers insight into cellular biology of colorectal cancer 2Research offers insight into cellular biology of colorectal cancer 3Louisiana Tech University researchers use 3D printers to create custom medical implants 2Louisiana Tech University researchers use 3D printers to create custom medical implants 3Researchers develop models to study polyelectrolytes, including DNA and RNA 2
(Date:8/22/2014)... THURSDAY, Aug. 21, 2014 (HealthDay News) -- The air ... U.S. Environmental Protection Agency reported Thursday. Significant progress ... in urban air in recent decades, the agency said ... been a nearly 60 percent reduction in mercury from ... decline in benzene, and an 84 percent fall in ...
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