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Tag: "provoke" at biology news

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...e genes through lateral transfer. "This study will provoke interest in what secrets may lie undiscovered in the sequences of other supposedly 'simple' amoeba genomes." Named for its effectiveness in killing other cells, E. histolytica was long considered to be a 'primitive' organism ?originating from the ti...

Inflammatory molecules released by pollen trigger allergies

How do pollen particles provoke allergic reactions? A new study in the February 21 issue of The Journal of Experimental Medicine puts some of the blame on bioactive molecules that are released from pollen. These molecules bind to immune cells and cause them to launch a typical alle...

UCSD researchers maintain stem cells without contaminated animal feeder layers

...ls were to be transplanted into people, they would provoke an immune system attack eliminating their therapeutic value. While several laboratories have attempted to grow stem cells in alternative cultures, problems have remained. In some cases, human feeder layers were developed but this added another measu...

UCLA scientists store materials in cells natural vaults

... will be compatible with living cells and will not provoke an immune reaction. Previous efforts have relied upon viruses or artificial chemicals to house and deliver drugs or other substances to targeted cells. RESEARCH: Scientists at the David Geffen School of Medicine at UCLA have exploited thousands of t...

Scripps scientists find potential for catastrophic shifts in Pacific ecosystems

...onment and that small, random physical changes can provoke an amplified response in the biology in ways that may not be easily or symmetrically reversed. These measurements show that asymmetrical and even irreversible ecological change is possible." Irreversibility means that if the ecosystem changes dramat...

New insights into how Huntington's disease attacks the brain

...icits toxic interactions from neighboring cells to provoke the fatal brain disorder. The May 5 edition of Neuron reports the findings. "This is really important because most current disease models and drug development efforts rely on the assumption that Huntington's disease arises from within the target bra...

Attacks of King George III's madness linked to key metabolism molecule

... of George III's hair contained arsenic, which can provoke porphyria attacks. The authors of that report suggested that, ironically, he may have been exposed to arsenic contamination of a substance his doctors gave him as treatment. PGC-1 alpha is a "transcriptional coactivator" that acts as an on-off switc...

Woods Hole Research Center plans controlled burn in Amazon rainforest

...es in the canopy; longer, more intense dry seasons provoke leaf thinning; and both of these changes allow the litter to become dry enough to sustain a fire. Once a forest has burned a first time, the combination of a more damaged forest canopy and a stock of larger fuel from trees killed by prior fires make ...

Taking a bite out of a fellow worker helps wasps recruit new foragers

...actions. O'Donnell said the biting did not always provoke an individual to begin foraging immediately, noting the biting seems to have a cumulative effect. Some insects were bitten multiple times for hours before leaving the nest to forage. "Going off the nest to forage, where they are exposed to all kind...

Manipulating single cell receptor alters animal behavior

...ts, both stimulated by the same cell receptor, can provoke different behaviors in mammals. The broad implica... kidneys and lungs produce enzymes that eventually provoke production of angiotensin. It previously was known that angiotensin has robust behavioral effects o...

Mayo Clinic researchers challenge sepsis theory

...h a change in certain cellular receptors that then provoke widespread inflammation, even in the absence of bacteria or their poisons. "We think people have been focusing too exclusively on a single causal factor of sepsis for the last 150 years and, as a result, therapeutically aiming at the wrong target --...

Pilot study successful in taming allergic reactions to food

...protection from accidental ingestion of items that provoke reactions and, eventually, to induce complete or near-complete tolerance to those items. Burks and his colleagues modeled the study on a commonly used method for treating seasonal allergy sufferers to alleviate symptoms. In this approach, called ...

Engineer ramps up protein production, develops versatile viral spheres

... into the bloodstream with the hope that they will provoke a strong, albeit general, response by the immune system. The process is akin to advertising a product to a random audience and hoping some consumers become interested. With an engineered capsid, in contrast, a vaccine maker could attach a very spec...

Nanoscale microscope sheds first light on gene repair

...ic material, DNA double-strand breaks. Such breaks provoke a rapid and highly coordinated series of events to identify and repair the damage. The response is critical, and there is an increased risk for cancer, developmental abnormalities and immunological problems when components of the repair processes ar...

Researchers discover surprising drug that blocks malaria

...o hijack red blood cells, then wildly multiply and provoke its life-threatening symptoms. "This opens the possibility for important new drugs for malaria that won't become resistant. New drugs are urgently needed because the parasite has evolved resistance against virtually all types of commonly used drug...

A new study of living cells could revolutionize the way we test drugs

... "We added ethanol ?which is essentially vodka ?to provoke a response from the cell. Ethanol is known to increase the transparency of cellular membranes which we hoped would give a signal we could detect," says Dr Irina Barbolina, who carried out the experiments. It worked. As soon as the yeast got a tast...

Researchers from the University of Navarra analyze new kinds of cancer-fighting antibodies

...re directed to the immune system cells in order to provoke a stronger reaction against cancer. This has the advantage of exploiting a mechanism with an action distinct from the other strategies currently being used to treat cancer, and is capable of interacting with the current treatments so as to make both ...

New vaccine prevents CMV infection and disease in mice

...hiding or masking the proteins that would normally provoke an immune response, or by fooling the immune system into mounting a response that doesn’t work to eradicate the virus. “We needed a way to make the host defense system sit up and take notice,” said Christopher S. Morello, Ph.D., first author of ...

Research shows cord blood comparable to matched bone marrow

... a group of proteins on bone marrow cells that can provoke the immune system to respond. When doing bone marrow or cord blood transplants, doctors generally try to have the donors’ and recipients’ HLA types match as closely as possible. Wagner added that increasing the inventory will increase the chance of...

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