Scripps scientists find potential for catastrophic shifts in Pacific ecosystems
..., market systems) and their dynamics and have been proven in small-scale ecological applications, medical applications, meteorological applications and in financial applications by investment banks. "We have shown by analyzing this data with these methods that there is a limit as to what our understanding ...Oldest cranial, dental and postcranial fossils of early modern European humans confirmed
...ublic, excavated more than 100 years ago, has been proven for the first time, through modern radiocarbon dating, to be the oldest cranial, dental and postcranial assemblage of early modern humans in Europe. A team of researchers from the Natural History Museum in Vienna, from the University of Vienna in Au...Supercomputers to focus brains on AIDS dilemma
...e, the target for the protease inhibitors that had proven so effective until the recent emergence of drug-resistant mutants. The new drug possibilities flow out of a long series of molecular dynamics simulations by McCammon's group. These simulations have focused on the catalytic domain of HIV-1 integrase,...Measles Deaths Worldwide Drop By Nearly 40% Over Five Years
...es (SIAs) every three to four years. The SIAs have proven especially effective. From 1999 to 2003, more than 350 million children throughout the world were vaccinated against measles through SIAs. As measles wards shut down all over the African continent, a long-term budget item in many hospitals can be fr...Live vaccines more effective against horse herpes virus
...know that the MLV has been in use for decades, has proven to be reasonably safe, and in -- my opinion -- it should be the vaccine of choice, at least in non-pregnant animals," said Klaus Osterrieder, associate professor of virology in the College of Veterinary Medicine at Cornell. The college is home to the...Promising new West Nile therapy cures disease in mice
...rly for people over 50. We currently do not have a proven therapy for people with serious West Nile disease, so we will continue to aggressively pursue all promising leads for an effective treatment," says Anthony S. Fauci, M.D., director of NIAID. Scientists do not know why some people infected with West ...50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel
...site is present in those proteins although not yet proven to operate. "Cells are fastidious in the way they regulate activity at their borders," Goldstein added. "Our work shows how sumoylation controls one important process at the cell surface and hints that it may influence others." Additional authors i...Nanoscale Diagnostic Sets Sights on Alzheimer's
...io-Barcode Diagnostic Method Could Rival PCR If proven successful in further clinical studies, the procedure could become the first tool for early diagnosis of Alzheimer's, and the first test to conclusively identify the disease in living patients. Chad Mirkin and William Klein of the National Science F...UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders
...l grant funding, Witte said. UCLA researchers have proven their skill at ushering scientific discoveries from the lab to modern medicine. Several targeted therapies were developed based on UCLA research, including Gleevec and the breast cancer drug Herceptin. Additionally, UCLA scientists played key roles i...PCRM develops world's first cruelty-free insulin assay
... medical labs will use it," said Barnard. "We have proven that if researchers are willing to make the effort, there are effective, humane alternatives to animal-based assays and other testing procedures--alternatives that could help save the lives of millions of people and animals." There are an estimated ...Beyond lithium for bipolar disorder
While lithium treatment has proven to be a godsend for many of the two million Americans with bipolar disorder, it is not without its downside. People on the drug may develop hypothyroidism, tremors, cognitive impairment, and excessive thirst and urination and gain weight. However, b...Scientists identify molecular events that drive cell senescence
...he symptoms sinceno therapies have been clinically proven to slow or prevent progressionof the disease. Amyloid protein deposits are present in the early phaseof the disease - a fact that suggests a gene vaccination would be astep forward in slowing the progression of dementia.From the mouse studies and in ...Gene vaccine for Alzheimer's disease shows promising results
...he symptoms sinceno therapies have been clinically proven to slow or prevent progressionof the disease. Amyloid protein deposits are present in the early phaseof the disease - a fact that suggests a gene vaccination would be astep forward in slowing the progression of dementia.From the mouse studies and in ...Study identifies predictors of HIV drug resistance in patients beginning triple therapy
...hinking. "Myhypothesis was this: While it had been proven that individually thechemicals don't impact nerve cell development, the combination of allthree might pose increased risks," she says.So Reinisch decided to test the chemical cocktail, in similarproportions to those found in Brick, on a species of su...Clam embryo study shows pollutant mixture adversely affects nerve cell development
...hinking. "Myhypothesis was this: While it had been proven that individually thechemicals don't impact nerve cell development, the combination of allthree might pose increased risks," she says.So Reinisch decided to test the chemical cocktail, in similarproportions to those found in Brick, on a species of su...Gene therapy converts dead bone graft to new, living tissue
...-growing proteins directly into the bone. This has proven successful for the small bone transplants used in spinal fusion, but not for larger grafts, because the proteins' effectiveness wear off in just hours. By contrast, the gene therapy method triggers the tissue surrounding the graft to produce the prot......nfections. Oral adenovirus vaccines have long been proven to be safe and effective. The researchers believe their process for constructing a replicating live recombinant adenovirus could lead to more economical vaccines that provide longer-lasting disease protection, which would be particularly beneficial f...