Neuronal 'traffic jam' marks early Alzheimer's disease
...transport hypothesis, then neuronal cultures could prove valuable in testing diagnostic and therapeutic approaches, said Goldstein. The researchers are also analyzing more brain tissue samples from humans with Alzheimer's disease, to confirm their findings of the early transport defects and their effects ...Termites feed through good vibrations
...have some signals that trigger attention ?that may prove useful in artificial intelligence. CSIRO entomologist Theo Evans says laboratory experiments have found that termites use their ability to detect vibrations to determine which food source is most suitable. The termites can also detect how the vibrat...Current human embryonic stem cell lines contaminated UCSD/Salk team finds
...therapy, thescientists said. However, it may still prove difficult to completelyeliminate the Neu5Gc, because is has become metabolically incorporatedinto the currently available, federally-funded human embryonic stemcell lines."With this discovery, the preexisting general concern about usinganimal product...Timing is everything: First step in protein building revealed
...rger shift, indicating a much bigger separation.To prove eIF1 was being released from the ribosome complex, theresearchers examined how fast the pieces of the ribosome come together,and how long it takes them to fall apart under various circumstances.Their results support the idea that two separate steps t...Novel Enzyme Shows Potential As An Anti-HIV Target
...SIRT1’s enzymatic activity, inhibiting SIRT1 could prove to be a promising anti-HIV therapy. Future study will have to verify whether inhibiting SIRT1 can successfully put the brakes on HIV transcription and control the virus (See also “A New Paradigm in Eukaryotic Biology: HIV Tat and the Control of Tran...Gene variations explain drug dose required to control seizures
...aid the researchers. A similar approach might also prove useful for other conditions, such as Parkinson's disease and cancer, in which patients' drug dosage requirements vary substantially, they added. Rigorous clinical study is required before any such method could be put into practice, the researchers e...Study shows nanoshells ideal as chemical nanosensors
...s that use a singlenanoshell, something that could prove useful for engineers who aretrying to probe the chemical processes within small structures such asindividual cells, or for the detection of very small amounts of amaterial, like a few molecules of a deadly biological or chemicalagent....Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
...r,?says Lachman.Lachman suggests the vaccine might prove helpful in keeping humanHER2/neu tumors from metastasizing, or spreading, but adds that thisnotion must be tested in human clinical trials.Lachman believes that the vaccine will address two additional safetyconsiderations “because it is built of RNA ...A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020
...r,?says Lachman.Lachman suggests the vaccine might prove helpful in keeping humanHER2/neu tumors from metastasizing, or spreading, but adds that thisnotion must be tested in human clinical trials.Lachman believes that the vaccine will address two additional safetyconsiderations “because it is built of RNA ...UCLA scientists transform HIV into cancer-seeking missile
...f many cancer cells. The UCLA team is the first to prove that modified HIV will target and bind with P-glycoproteins. "P-glycoproteins cause big problems by making the cell resistant to chemotherapy," said Chen. "They act like soccer goalies and punt therapeutic drugs out of the cancer cell. This prevents...New Breast Cancer Test Could Save Lives
... women are dependent on self-examination which can prove unreliable. This latest technology has the ability to image through dense breast tissue, and therefore can reach a far wider section of women than X-ray mammography can. Women below 50 in particular will benefit from this new test, which is much mor...Key Trigger Of Opioid Withdrawal Symptoms Found
..."suggesting that neurotransmitter transporters may prove to be useful targets for management of opioid dependence," they wrote. The researchers also wrote that, since GABA is a neurotransmitter that inhibits nerve impulses, drugs to inhibit the GABA transporter "could produce their therapeutic effect throu......small protein fragments (known as "peptides"). To prove this, the researchers produced a synthetic "perfume" containing a mixture of protein fragments. By manipulating the combination of fragments in the perfume, the sexual attractiveness of males could be increased. In the experiment none of the females ...Chemists identify key gene in development of type 1 diabetes
...d ISO-1 to block the MIF protein. If human studies prove the effectiveness of ISO-1, the compound or its derivatives could ultimately save lives, reduce health care costs and help prediabetic people, particularly children, avoid a lifetime of insulin injections, Al-Abed says. Prediabetic individuals are th...Towards precise classification of cancers based on robust gene functional expression profiles
...d ISO-1 to block the MIF protein. If human studies prove the effectiveness of ISO-1, the compound or its derivatives could ultimately save lives, reduce health care costs and help prediabetic people, particularly children, avoid a lifetime of insulin injections, Al-Abed says. Prediabetic individuals are th...Antibiotic might fight HIV-induced neurological problems
...to proceed with a clinical research trial first to prove its safety and efficacy against HIV-associated cognitive impairment." SIV and HIV both affect the same tissues in the same way and use the same tricks to infect cells and outwit treatments, but SIV infects only non-human primates, and HIV only infec...Effective Cancer Treatments Follow The Clock
...ircadian machinery to the immune system that might prove to be useful drug targets.?/p>...LUCA technologies confirms real-time methane generation
...mple, the Daqing Field in Northeast China -- could prove to be important sites for the bioconversion of residual oil to methane and the restoration of these 'spent' sites to economic energy production." Potential for Methane "Farming" It has long been known that certain microorganisms are "methanogens" ?......rt cell differentiation. And with time, they might prove an important resource for developing cell-based therapies for heart disease. ### Citation: Winitsky SO, Gopal TV, Hassanzadeh S, Takahashi H, Gryder D, et al. (2005) Adult murine skeletal muscle contains cells that can differentiate into beating ca...Scientists identify molecule that regulates well-known tumor suppressor
...ining the prognosis of some human cancers, and may prove to be a suitable target for cancer therapy. The phosphatidylinositol 3' kinase signaling pathway regulates cell growth and survival, and is inhibited by activity of the tumor suppressor PTEN. Research indicates that PTEN exerts its tumor suppressor ...