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Tag: "protocol" at biology news

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

...land cancerous tissues. The labs followed a common protocol for allsteps of sample preparation and microarray analysis and the resultinggene expression profiles were analyzed and compared.Sample correlation within each lab was extremely high; microarray datafrom the RNA samples had the highest correlation val...

International trial of two microbicides begins

...N 035) is available at www.hptn.org/index.htm. The protocol chair of the study is Salim Abdool Karim, MBChB, Ph.D., of the University of KwaZulu-Natal in Durban, South Africa. ...

MetaChip provides quick, efficient toxicity screening of potential drugs

...N 035) is available at www.hptn.org/index.htm. The protocol chair of the study is Salim Abdool Karim, MBChB, Ph.D., of the University of KwaZulu-Natal in Durban, South Africa. ...

Ophthalmologists Use Artificial Silicon Retina Microchip To Treat Vision Loss

...Medical Center and Rush. Pollack says the current protocol has been modified to reduce the likelihood of inadvertant scientific bias. "We operated on the right eye of each of the initial 10 patients. For the next 20 patients we will randomly select which eye will receive the ASR chip. In addition, post-opera...

Ophthalmologists implant five patients with artificial silicon retina microchip

...Medical Center and Rush. Pollack says the current protocol has been modified to reduce the likelihood of inadvertant scientific bias. "We operated on the right eye of each of the initial 10 patients. For the next 20 patients we will randomly select which eye will receive the ASR chip. In addition, post-opera...

Alzheimer's cognitive decline slowed

...ed five week later. As a result of the bleeds, the protocol was redesigned to perform the procedure under general anesthesia and all subsequent procedures were performed without complication. Cognitive outcomes were assessed in the six patients who completed the NGF delivery procedure safely. The Mini Mental...

Roche clinical trial registry and results database launched

... are proud to go live with our publicly accessible protocol registry and clinical trial results database today...roach on the databases and will ultimately include protocol information and results from all Phase II to Phase IV clinical trials completed after 1 October, 200...

Biomarkers isolated from saliva successfully predict oral and breast cancer

... goal is to provide the optimized and standardized protocol to assure consistent results." The studies are supported by grants from the U.S. Public Health Service (National Institute of Dental & Craniofacial Research) and the UCLA Jonsson Comprehensive Cancer Center to David T. Wong. ...

OneWorld Health drug receives 'Orphan' designation from U.S. and European regulatory agencies

...zil. The U.S. Orphan Drug Act provides for formal protocol assistance when requested by the sponsors of drugs for rare diseases or conditions. The EMEA regulations are similar, and have the added advantage of applying to all 25 members of the European Union. Orphan Drug Designation also provides incentives s...

Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX

...w GeneChip(R) Globin-Reduction kits and associated protocol developed in conjunction with PreAnalytiX -- a joint venture between QIAGEN N.V. (Nasdaq: QGEN; Frankfurt, Prime Standard: QIA) and BD (Becton, Dickinson and Company). The new kits optimize the PreAnalytiX PAXgene(TM) Blood RNA System for use with Af...

Study Finds Moderate Hypothermia A Safe Treatment For Traumatic Brain Injury In Kids

..., mortality and complications during the treatment protocol and during hospitalization, the study also assessed functional and cognitive outcome in these children with severe traumatic brain injury. After severe TBI, 48 children less than 13 years of age admitted within six hours of injury were randomized by...

Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease

...to formulate and submit to the FDA a pivotal trial protocol for the use of STN AAV-GAD in the treatment of Parkinson's disease. "The results of the trial are highly encouraging, in terms of both safety and efficacy," stated Eric J. Nestler, M.D., Ph.D., member of the Neurologix Scientific Advisory Board and ...

Results of world's first gene therapy trial for arthritis show approach safe, feasible

...rial of its kind and safety was a key concern, the protocol was designed so that the gene would be delivered t... otherwise healthy patient population, the ex vivo protocol was the most appropriate approach to take at the time," stated Paul Robbins, Ph.D., professor of mol...

Computers close in on protein structure prediction

...ns from other genomes, such as a mouse or fly. The protocol was first tested on a blind annual prediction test considered to be the highest standard for removing bias from protein structure prediction models. "We can't compute the energies perfectly, but the biggest problem is the search through possible sha...

DNA from feathers tells tale of eagle fidelity

..., but this is a first for birds." By developing a protocol for extracting DNA from feathers, the researchers also have added another tool to help conservation biologists study rare and elusive birds of prey. The researchers used a technique called DNA fingerprinting to help them genetically "tag" individual...

Updated data on novel HPV vaccine confirms efficacy in large population

...he vaccination period or who may have violated the protocol (e.g. by missing visits, etc.), the vaccine prevented 99 percent of HPV 16 or 18-related high-grade cervical pre-cancers (1 of 9,342 pts versus 81 of 9,400 in the placebo group) with an average follow up of 25 months. The vaccine was generally we...

Bacteria in Household Dust May Trigger Asthma Symptoms

...nducted a home inspection, and used a standardized protocol to collect samples. Dust samples were collected from bedroom, kitchen and living room floors, bedding, and upholstered furniture and assayed for endotoxin. A disease association analysis was performed to correlate endotoxin concentrations to specific...

New cell transplantation technique restores insulin production in diabetics

...correct needle placement. "We used a steroid-free protocol to suppress the immune system, so that the body accepted the transplanted cells," Dr. Krishnamoorthy said. "We also developed a 'sandwich technique' to close the access site through the skin, where the islet cells are injected. The sandwich technique...

Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool

A standard Internet protocol that checks errors made during email transmissions...tivated and we just don't see them turning on. Our protocol will offer greater overall sensitivity in detecting the expression of any gene, even if a gene turns...

Diabetes researchers pioneer islet cell xenotransplantation in primate studies

...o diabetic rhesus macaques using an anti-rejection protocol developed by Drs. Christian Larsen and Kenneth Cardona of the Yerkes Research Center and the Emory Transplant Center. The isolation method developed by the U of A researchers is simple and reproducible with the neonatal pig islets having some growth ...

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