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Tag: "proteomics" at biology news

How to steer a moving cell

...have developed new technology which, combined with proteomics ?the large-scale study of the structure and functi...s from several disciplines ?biologists, chemists, proteomics researchers and computational biologists who can integrate large data sets ?have applied a global ap...

Mine runoff continues to provide clues to microbial diversification

...o might have implications into helping study human proteomics because not everyone’s individual genome will be sequenced.? The pink microbial biofilm communities found in the mine runoff provide perfect research subjects because they have fewer organisms than most communities found in nature. The reason, Hett...

Scientists use nanoparticle to discover disease-causing proteins

.... "The problem with the current method of using proteomics - protein profiling - is that we use very small sample amounts so sensitive that we can't effectively use existing technologies to study them," Tao said. "In addition, to study a specific protein and its function, we want to preserve its natural envi...

Proteins may predict lung transplant rejection

...and those who did not. The researchers combined proteomics (the study of proteins), the latest in mass spectrometry technology and the best analytical methods from the field of bioinformatics (the use of computers and statistics to analyze and find patterns in scads of data). They hypothesized that proteins ...

Newly identified biomarker detects and regulates spread of brain tumors

...ples from patients with various CNS diseases using proteomics to examine simultaneously all proteins in biological samples. To validate the study's results, attractin levels in a set of 100 normal and tumoral brain samples also were examined. The researchers found elevated attractin levels in 97 percent of mali...

Researchers in Montréal and the US create model of key immune-system component

... in infections by using a global approach based on proteomics and genomics. This approach will expedite developm...nes. The major investments made in recent years in proteomics research in Québec and Canada have enabled us to pool our resources and apply promising new approach...

Study offers innovative profile of enzyme that aids tumor growth

...sible due to the availability of an activity-based proteomics probe for this enzyme. Such probes are now available for many enzyme classes that participate in cell metabolism, so Cravatt suggests "a large swath of the enzyme proteome" could be addressed using the study's experimental strategy. "The success...

Scientists make first step towards 'holy grail' of crystallography

...y acute with the advent of structural genomics and proteomics which aim to determine the structures of thousands of proteins. Protein crystallography plays a major role in this understanding because proteins, being the major machinery of living things, are often targets for drugs. To direct the proteins to be...

Two NIH initiatives launch intensive efforts to find roots of common diseases

... to those influences, using new tools of genomics, proteomics and metabolomics. "Differences in our genetic makeup certainly influence our risks of developing various illnesses," said David A. Schwartz, M.D., Director of the National Institute of Environmental Health Sciences, also part of NIH, and co-chairman...

Salmonella caught red-handed

...els is largely lacking. Infection biologists and proteomics researchers have now identified all the proteins involved in Salmonella metabolic paths during an infection. Dirk Bumann of Hannover Medical School led a team including Daniel Becker, Claudia Rollenhagen, Matthias Ballmaier and Thomas Meyer of the Ma...

Next good dinosaur news likely to come from small packages

...eveal the history of life on Earth. But tacking on proteomics means scrutinizing life at a molecular level ?life that existed thousands of years ago. Ostrom's work has spanned from examining organic matter in meteorites to reconstructing who eats who in the food web from the tropics to the arctic. The trail is...

The closest look ever at the cell's machines

...he set with the highest quality," Aloy says. "Most proteomics studies in the past have shown whether molecules interact or not, in a 'yes/no' way. The completeness of this data lets us see how likely any particular molecule is to bind to another. By combining such measurements for all the proteins in the cell, ...

Novel protein complex enables survival in hostile environment

...," Johnson said. By use of genome-sequence-driven proteomics techniques, they identified the gene for the enzyme. A search showed that this gene exists only in hydrothermal vent methanogens and their close relatives, but not in other microorganisms. From the sequence of the fsr gene, Johnson and Mukhopadhya...

Micro RNAs play role in egg making

...e process of oogenesis and fertilization. Using a proteomics tool developed at Carnegie Mellon, the scientists compared maturing fruit fly eggs. One group of eggs was missing a gene essential for producing miRNAs, whereas another group of eggs had normal miRNA production. (All plants and animals have DICER, th...

Rutgers to lead $52.7 million protein research program

...e basis for plans to greatly expand our efforts in proteomics and related disciplines," added McCormick. The research program will be funded by the Protein Structure Initiative (PSI) of the National Institute of General Medical Sciences (NIGMS), one of the National Institutes of Health. "With demonstrated expe...

Nanowires can detect molecular signs of cancer, scientists find

...h high selectivity and sensitivity. "Genomics and proteomics research has elucidated many new biomarkers that have the potential to greatly improve disease diagnosis," the scientists write. "The availability of multiple biomarkers is believed to be especially important in the diagnosis of complex diseases like...

Proteomics brings researchers closer to understanding microbes that produce acid mine drainage

...sm. That's at least as good as most people do with proteomics on single organisms growing in the laboratory," Banfield said. "The exciting thing to me is we can start to study the organisms in situ, and that's really a big step forward." Of the 2,033 proteins detected, 572 were unique to the biofilm bacteria. ...

Team Invents Device For Weighing Individual Molecules

...ules based on their weight. Today, high-throughput proteomics searches are often done at facilities possessing a...his, the team will likely collaborate with various proteomics labs for side-by-side comparisons of already known information on the mass of biological molecules w...

Product improves peptide identification for proteomics research

... 80 percent more peptides than preceding models in proteomics applications, such as protein identification and b...ce and productivity are essential, particularly in proteomics research." "The LC/MSD Trap XCT Ultra is the latest example of Agilent's integrated approach to fac...

Integration of Agilent's MS technology, Proteome Systems' software to help scientists in proteomics research

...: A) and Proteome Systems, a leading international proteomics company, today announced they have signed a market...yze and integrate complex data on the forefront of proteomics research." ...

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