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Tag: "proteins" at biology news

FSU researchers determine a critical factor in workings of proteins

Scientists know that a better understanding of how proteins bond could lead to more effective treatments for g... department of physics. "Rapid association between proteins is crucial in a wide array of biological processes, such as the utilization of and defense against t...

Proteins important in Alzheimer's, Parkinson's disease travel in the slow lane

...vania School of Medicine have been able to observe proteins important in Alzheimer’s and Parkinson’s disease m... along axons, extensions of nerve cells that carry proteins away from the cell body. Understanding this process of axonal transport is important for studying ma...

Scientists find new genetic clue to cause of Alzheimer's disease

...heir search for genetic influences amid a group of proteins that transport APP within cells, looking for small changes, or "misspellings," in seven genes involved in moving APP within cells. To start, the scientists combed two large data sets of genetic information from families in which more than one pers...

Researchers find hepatitis A and hepatitis C attack same protein to block immune defenses

...triggers antiviral responses. "With 30,000-plus proteins in the cell, it’s really remarkable that these two...r the survival of any virus in the liver." MAVS proteins project from tiny structures called mitochondria, which are found in large numbers in each liver cel...

HIV protein enlisted to help kill cancer cells

...e can do this, we've started creating a battery of proteins that can push cancer cells to die." Hawkins says...ar biology and pharmacology. Hotchkiss was seeking proteins that inhibit apoptosis in patients with life-threatening infections and found that TAT-Bim had the u...

Cheaper, better disease treatments expected from faster approach to developing antibodies

...sed as factories to produce antibodies (protective proteins of the human body that fight viruses, cancer cells and other harmful agents). However, previous approaches required an antibody that looked promising to be transferred from bacteria to mammalian cells to pursue large-scale, commercial production. ...

Producing medicines in plant seeds

Using plants to produce useful proteins could be an inexpensive alternative to current med...versity have succeeded in producing in plant seeds proteins that have a very strong resemblance to antibodies. They have also demonstrated that these antibody v...

Inflammation may play role in metastasis of prostate cancer

...n of metastasis," said Karin. "We have shown that proteins produced by inflammatory cells are the 'smoking gun' behind prostate cancer metastasis. The next step is to completely indict one of them." One in six men will be diagnosed with prostate cancer, and one in 33 will die of metastatic disease. Early...

Notorious cancer gene may work by destroying messenger

...omote cancer by causing PMR1 to halt production of proteins that normally put the brakes on cell growth ?tumor...ls use that mechanism to control the production of proteins such as growth factors, which activate genes in response to a hormone or other signal. PMR1 also...

Einstein's tea leaves inspire new blood separation technique

...). Separating blood plasma from red blood cells, proteins and other microscopic particles is an essential step in many common medical tests, including those for cholesterol levels, drugs in athletes, blood types in donors and glucose levels in diabetics. Current testing requires samples to be taken in a doc...

Scientists map key landmarks in human genome

... features," said Fisher. Transcription factors are proteins that bind to particular DNA sites in "promoter" re...ore, like ribbon around a spool that is made up of proteins called histones, and the nucleosomes are located along the chromosomes like beads on a string. Nu...

Applied scientists create wrinkled 'skin' on polymers

...ing of flow at very small scales and stretching of proteins and DNA. These new efforts, while at early stages of development, are very promising." ...

Scientists create dual-modality microbeads to improve identification of disease biomarkers

...ads are mixed in a liquid such as urine. Viruses, proteins or other biomarkers are captured on the bead surfa... virus in the liquid sample based on the number of proteins or viruses attached to the surface of the beads. Tushar Sathe, a graduate student in the Wallace...

Chemical switch triggers critical cell activities

...et another NEDD8. By continually passing the NEDD8 proteins from the right hand to the left hand and on to E2,...ay crystallography, scientists bombard crystals of proteins with X-rays and use the patterns formed by beams bouncing off the crystals to create computer-genera...

Scientists discover a new risk factor for Alzheimer's

...m reasoned that inherited defects in some of these proteins might cause more APP to be shunted into endosomes, causing more amyloid-beta to be made, thereby increasing risk for Alzheimer's. When the team investigated these genes, only SORL1 was associated with an increased risk of Alzheimer's. "What we hav...

Researchers hot on the trail of brain cell degeneration

...the study, the Rho protein, belongs to a family of proteins able to influence signals that had been linked to cell degeneration. The two teams' analysis demonstrated that over-stimulation causes activation of Rho as well as cell destruction signals. Blocking Rho activity by genetic modification keeps the prot...

Nanotechnology shows promise as next wrinkle fighter

...sting polymer films, by applying various cells and proteins to see if there are toxic reactions. ...

Cancer researchers add spice to research against rare neuromuscular disease

...ses, the extra amino acids become part of abnormal proteins that clump up inside neurons, creating a clog that can bring normal molecular activity to a standstill. The clumps of material eventually become toxic to neurons. In Kennedy's disease, a vital molecule known as CREB-binding protein or CBP becomes ...

Freeze! Scientists film proteins at work by freezing them at different states

...his week in Science. Most of the research done on proteins is based on their study in a resting state and the... the field? Bourgeois explains. Filming certain proteins whilst reactions occur has been possible at the ESRF for some years. However, experiments until toda...

Jefferson researchers' discovery may change thinking on how viruses invade the brain

... dynein-LC8 interaction, and attempt to find other proteins that could be involved in viral transport. ...

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