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Tag: "proteins" at biology news

Effect on breast tumors of DNA alternations in 3 genes described

...s genes that promote normal cell growth to produce proteins that cause malignant behavior, or unregulated cell growth. Until now, data has been very limited regarding the mechanism and causes of hypermethylation, especially for hypermethylation in breast cancer. The purpose of the current study was to determ...

First demonstration of new hair follicle generation in an animal model

...ofessor of Dermatology. “The wnts are a network of proteins implicated in hair-follicle development.? Resear... we can influence wound healing with wnts or other proteins that allow the skin to heal in a way that has less scarring and includes all the normal structures o...

Decoding protein structures helps illuminate cause of diabetes

...ures quickly and accurately enough to catch moving proteins in mid-fold and see the shapes of intermediate ste...atoms. Though often depicted as static blobs, proteins are more like collections of balls and springs, constantly in motion, and their endless atomic twitc...

Newly identified mechanism for silencing genes points to possible anti-cancer strategies

...the individual cells to produce the many different proteins that make up the body. Scientists are only beginni...f human genes, for example, are actively producing proteins in a given cell at a given time. The remaining 90 percent are silenced by a various mechanisms that ...

Study of protein folds offers insight into metabolic evolution

...tein evolution, the researchers examined metabolic proteins at the level of their component structures: easily recognizable folds in the proteins that have known enzymatic activities. These protein domains catalyze a range of functions, breaking ...

Danish researches solve virus puzzle

...ploits the machinery of human cells to produce the proteins which the virus needs in order to replicate to bil... a 'cook book' which contains the recipes of which proteins the virus needs for replication. The work process of a virus The cell has ribosomes, a kind ...

Discovery of 'master switch' for the communication process between chloroplast and nuclei of plants

... Many of the nuclear genes that encode chloroplast proteins are regulated by a "master switch" in response to environmental conditions. This "master switch," like a binary computer, can activate or de-activate certain sets of genes based on stress signaling processes. "One of our suggestions in the paper i...

Individuals and populations differ in gene activity levels, not just genes

...ger" RNA is produced, leading to formation of more proteins corresponding to that gene. Those proteins are the building blocks that make up living cells and tissue. "The difference between genetic inf...

Proteasome activator enhances survival of Huntington's disease neuronal model cells

...y and from clogging up with damaged proteins. When proteins or peptides mutate, they can present major problem...on would improve catalytic degradation of abnormal proteins in HD. We first genetically engineered proteasome activators involved in either non-ubiquitinated pr...

Uniform language for describing genes of pathogenic and beneficial microbes

...r scientists to compare the functions of genes and proteins in a wide range of disease-related organisms. The ongoing initiative is part of the Plant-Associated Microbe Gene Ontology (PAMGO) project, a recently-established interest group of the worldwide Gene Ontology Consortium. The GO Consortium has been w...

York mathematician probes geometric route to combat viruses

...ave highly symmetrical external shells formed from proteins that encapsulate the viral genome. Dr Twarock has ... protein shells that pinpoint the locations of the proteins and the bonds between them. With collaborators Professor Cristian Micheletti, from the International...

Deconstructing brain wiring, one neuron at a time

...combinant rabies virus could contain genes for any proteins of interest, Callaway says, and he adds that once scientists can identify a neural circuit, they can then deactivate it, and test for changes in brain function. ...

Lighting up life: Cold Spring Harbor Protocols presents tips for creating glowing plants

...choosing appropriate plant tissues, designing test proteins for maximal GFP detection, and setting up microscope equipment for imaging in plants. This information will be useful to a broad range of scientists interested in plant biology and imaging technologies. A second freely accessible article ( http:...

Natural antibiotics yield secrets to atom-level imaging technique

...d gastrointestinal tracts also crank out the short proteins in response to invading pathogens. In addition to fighting bacteria, AMPs attack viruses, fungi and even cancer cells, so drugs designed to mimic them could have widespread medical applications, said Ramamoorthy, who is an associate professor of c...

Cure for cancer one step closer

...ogenic vials which will help preserve the tissue's proteins and genetic material almost indefinitely. The Wesley Research Institute is a leading medical research facility with a commitment to patient care, ethical conduct and quality research that aims to improve quality of life through better diagnosis an...

Sandia researchers take new approach to studying how cells respond to pathogens

... red and give researchers the opportunity to track proteins and see, for example, the dynamic cellular production of proteins or protein-binding processes inside or on the surface of the cells. The team is developing one pl...

Blood sugar's manufacture limited by building blocks' supply

...ino acids. Amino acids are the main ingredients of proteins and the source of a key substrate in blood sugar's production. "Gluconeogenesis is a complicated process," said Mukesh K. Jain of Case Western Reserve University. "It fundamentally requires two big things: the building blocks and the [glucose-buil...

Jefferson scientists find rabies-based vaccine could be effective against HIV

...tically weakened rabies virus to ferry HIV-related proteins into animals, in essence, vaccinating them against...ested the effects of inserting two different viral proteins into the rabies virus genome, and using such viruses-based vaccines in preventing disease in rhesus ...

Gut research yields new anti-cancer approach

...small molecule dramatically reducing levels of the proteins called tubulins, the building blocks of cancer cel.... Gut tumor cells have evolved to include "efflux" proteins that recognize standard chemotherapies as foreign, and "pump them out" of tumor cells. Even for brea...

A 'traffic light' for neurons means 'go' for improving brain research

...irus to insert genes for producing light-sensitive proteins into cells of interest. The gene ChR2 is derived from an algae that makes affected neurons more active when exposed to blue light. Deisseroth and collaborators first showed this in a paper in Nature Neuroscience in 2005. In this week's paper, they de...

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