protein 2 5

Tag: "protein" at biology news

Deconstructing brain wiring, one neuron at a time

...g discovered as a postdoctoral fellow at UCSF. The protein that ordinarily coats rabies virus particles was r...ess the bird virus's receptor, a bird cell surface protein known as TVA. Such neurons will then be "disguised" as bird cells and the rabies virus ?now acting l...

NIDA study identifies genes that might help some people abstain from smoking

...nnect to their neighbors) and a cyclic G-dependent protein kinase gene, which plays a key role in normal brain development. In addition to genes implicated in intracellular signaling and intercellular interactions, a number of genes involved in other processes have also been identified. While many of the ge...

Lighting up life: Cold Spring Harbor Protocols presents tips for creating glowing plants

...st over a decade ago, biologists isolated a unique protein from jellyfish that could be inserted into other o...te a brilliant green color. This green fluorescent protein (GFP) has allowed biologists to make many new discoveries regarding how living cells function. But o...

Natural antibiotics yield secrets to atom-level imaging technique

...used to construct a detailed image of a peptide or protein and to reveal how it sits in the cell membrane," providing clues for modifications that might make synthetic AMPs even more effective in overcoming ever-increasing bacterial resistance. For instance, rearranging parts of the molecule might make it fi...

Researchers develop marker that identifies energy-producing centers in nerve cells

A protein that causes coral to glow is helping researchers a...he central nervous system. This fluorescent marker protein may shed light on brain cell defects believed to play a role in various neurological diseases. The r...

Investigating the measles virus as a tool to kill multiple myeloma

... Laboratory strains of measles virus seek out this protein and use it as a receptor by which to enter the can...oncentrates iodine. This characteristic of the NIS protein can be exploited as a target in cancer therapy because it can concentrate radioactive iodine, thus p...

Scientists identify pancreatic cancer stem cells

...c than cancer cells that did not have one of three protein markers they believe to be associated with pancrea...solate those that had one or more of three surface protein markers -- CD44, CD24, and ESA. They chose these markers, called cell adhesion molecules, because t...

NIH researchers discover protein that appears to regulate bone mass loss, the cause of osteoporosis

...used by a deficiency in an important immune system protein known as CD40 ligand. This protein is crucial for the development and maturation of immune cells, and without it people with X-linked H...

Heart failure: Intervention possibilities from imaging programmed cell loss

... attached a radioactive substance to annexin A5, a protein that binds to dying cells, said Hofstra. They then used nuclear imaging that produces three-dimensional computer-reconstructed images to reveal information about both structure and function to measure the amount of annexin A5 absorbed. Annexin A5 bou...

Sandia researchers take new approach to studying how cells respond to pathogens

...cell selection and sorting followed by analysis of protein content in the selected cell subpopulations. "I... dimensions. The end results of the imaging and protein analysis are large amounts of data that must be categorized and understood. Computational modeling i...

Jefferson scientists find rabies-based vaccine could be effective against HIV

...he surface of HIV, while the other was an internal protein from simian immunodeficiency virus (SIV). They use... They then developed a new vector, a viral surface protein from another virus, vesicular stomatitis virus (VSV). Two years after the initial immunization, they...

Gut research yields new anti-cancer approach

...mmation of encouraging the action of the PPARgamma protein (with activator compounds) against discouraging it...mma inhibition destroyed cancer cell microtubules, protein structures that form part of the skeleton of cells. Beyond providing structural support and shape...

Gene tests and brain imaging reveal early dementia

...s based on the well-established fact that the APOE protein affects the risk of developing Alzheimer's. APOE is a lipid-transporting protein important in, amongst other things, the repair of cerebral neurons. Roughly one person in five carri...

Scientists identify molecular cause for one form of deafness

... Researchers have now learned that mutations in a protein called espin can cause floppiness in tiny bundles of protein filaments within the hair cells, impairing the passage of vibrations and resulting in deafness. Fi...

Aspirin discovery may improve cancer treatments

...ed the effects of salicylates on the inhibition of protein synthesis. "Our research showed that treating ...nslation initiation factor eIF2Ą, thus inhibiting protein synthesis," Professor Williams said. "Inhibiting or slowing down protein synthesis reduces the ac...

Researchers design pulsed mircrojet system to deliver protein drugs without pain or bruising

...novel pulsed microjet system engineered to deliver protein drugs into the skin without the pain or bruising t...formed every year for the delivery of vaccines and protein therapeutics such as insulin, growth hormone and erythropoietin, a red blood cell booster. Needle-f...

Changes in amino acids in the 1918 influenza virus cut transmission

...ied two key molecular structures: hemagglutinin, a protein located in of the surface of the influenza virus, and sialic acid, a cellular molecule that is recognized by hemaglutinins of both human and avian strains of influenza virus. These molecules are key to initiation of infection. There are 16 different...

Fascinating spider silk

...n spider (Araneus daidematus). While purifying the protein by dialysis, the researchers observed the separati...erent fluid phases. Whereas one phase consisted of protein dimers, the second consisted of oligomers—multiple protein units linked together. After the addition...

Mutation improves memory, may lead to memory-enhancing pill

...found the first genetic evidence that control over protein synthesis plays an important role in the formation...e is control at the level of translation—in making protein from messenger RNA, a less appreciated mode of regulation." When the regulatory protein eIF2a is ...

Researchers identify gene involved in dog size

...hat variation in one gene—IGF-1, which codes for a protein hormone called insulin-like growth factor 1, is very strongly associated with small stature across all dog breeds studied. “We have been intrigued by the population structure of dogs, which over the years have been selectively bred, allowing us t...

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