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Tag: "protein" at biology news

Salk scientists hammer out a pathway that promotes muscle cell survival in mice

...lar switch, called cAMP responsive element binding protein (CREB), had hunched backs, muscle wasting, and other signs of unhealthy muscles. Although CREB had long been studied for its role in glucose regulation in metabolic tissues like the liver and pancreas, its function in muscle tissue was unknown. Then,...

Machine preservation may promote more organ sharing

...igh blood pressure, stroke or elevated levels of a protein called creatinine. Levels of creatinine, which is produced by muscle, are used to determine kidney function. The current study included 120 ECD kidney transplants -- 95 kidneys were preserved with machine and 25 with simple cold storage preservat...

Protein enables discovery of quantum effect in photosynthesis

...University in St. Louis, did when he contributed a protein to a study performed by his collaborators at Lawre...s moniker? The taco shell protein. Taco shell protein It's called bacteriochlorophyl (BChl) a protein, but Blankenship fondly calls it the taco shell ...

'Insulator' helps silence genes in dormant herpes virus

... during a latent period, the virus binds to a host protein called CTCF, a protein known to act as an insulator in mammals and in fruit flies. What's more, the findings revealed that ...

Gene malfunctions cause schizophrenia, depression symptoms in mice

...d biochemical abnormalities in the function of the protein produced by the DISC1 gene. The researchers concluded that the different effects of antipsychotic and antidepressant drugs on the two mutant strains "might provide clues to effective medications for these patient groups. Indeed, these mice could r...

pHLIP, a novel technology to locate and treat tumors

...nd potentially treat tumors using a short piece of protein that acts like a nanosyringe to deliver “tags?or t...ademy of Sciences. The researchers show that, the protein fragment, called “pHLIP?(pH (Low) Insertion Peptide) can be injected into the abdomen of a mouse, fi...

The sound of proteins

Biologists have converted protein sequences into classical music in an attempt to he...attempts, which have focussed on DNA sequences and protein folding, and hence closer to the musical depth of popular compositions. They are currently piloting ...

Vaccine prevents prion disease in mice

...mentia and abnormal limb movements. Prion is a protein that is also an infectious agent. The proteins are so similar to proteins found normally that the immune system does not fight them off. To develop a vaccine that would stimulate the mice's immune system, researchers attached prion proteins to a gene...

Keeping the immune system from starting a 'food fight'

...ess. The researchers found that animals lacking a protein enriched in fat cells, called STAMP2, develop acut...onsume an overload of nutrients, the flood control protein may become overwhelmed and give out, leading to the chronic, low-grade inflammation characteristic o...

Simple home spit test to spot deadly pre-eclampsia

...oms are raised blood pressure and the excretion of protein in the urine. While there is no cure, other than the delivery of the baby and removal of the faulty placenta, early detection and management of the problem can have a big impact on patient outcome. ...

Anthrax paralyzes immune cells with lethal toxin, UF research shows

...a pair of scissors, snipping off the ends of a key protein and preventing the transmission of messages within...d form of the toxin, as well as images showing how protein expression changed in cells. After scrutinizing the images for hours, During finally identified one ...

How to steer a moving cell

...ing. The researchers hope to fully define the protein components of the compass to gain a better underst...tic cell in order to analyze the components of its protein network. The cell fractionation equipment developed in Klemke’s lab is the first method to enable r...

Newborn neurons like to hang with the 'in' crowd

...ed a virus carrying the gene for green fluorescent protein into the hippocampus, a brain region harboring neu...ously identified a subunit of the NMDA receptor, a protein complex that transduces signals sent by neighboring cells, as the newborn neurons' life-saving equip...

Genetic roots of bipolar disorder revealed by first genome-wide study of illness

...oot of the lithium-sensitive pathway than does the protein that lithium is thought to target. Scientists can now try to develop more effective medications by focusing on new compounds that act on the DGKH enzyme or regulate how much of the enzyme is produced. The DGKH gene is on chromosome 13. Several o...

Gene mutation linked to cognition is found only in humans

...w study showed that a certain form of neuropsin, a protein that plays a role in learning and memory, is expre...as the extra 45 amino acids in this form may cause protein structural and functional changes. They note that in order to understand the genetic basis that unde...

New Brandeis research sheds light on memory by erasing it

...s by manipulating a so-called "memory molecule," a protein kinase known as CaMKII. "The core problem in memory research has been understanding what the storage molecule actually is. Identifying this molecule is essential to understanding memory itself as well as any disease of memory, " explained lead auth...

Molecule that destroys bone also protects it, new research shows

...tion site," Gaffen said. IL-17 is a cytokine, a protein hormone made by "T helper" cells of the immune system that stimulate immunity. Gaffen noted that until recently, immunologists believed there were only two major types of "T helper" cells -- TH1 and TH2 -- which were believed to be responsible for ne...

Scientists identify prion's infectious secret

...dt-Jakob disease, result from a kind of infectious protein called a prion. Remarkably, in recent years resear...arrays—glass slides covered with thousands of tiny protein fragments. Traditionally, these arrays are used for finding binding sites within well-behaved protei...

Survival of the rarest: Fruit flies shed light on the evolution of behavior

..."tagged" one of the types with a green fluorescent protein that glows under ultraviolet light. Then, over the course of a year, Fitzpatrick sat in a darkened room for several hours a day counting glowing larvae under a microscope. The researchers found that when the fruit fly larvae were competing for foo...

LIAI scientists make important finding on cytomegalovirus transmission

... used an antibody to block the action of the IL-10 protein in the salivary glands of mice by inhibiting binding of IL-10 to its receptor. "IL-10 is a messenger molecule which suppresses the protective T cell response that would normally attack the cytomegalovirus," he said. "By blocking the ability of the ...

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