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Tag: "protects" at biology news

Newly found sensing system enables certain bacteria to resist human immune defenses

...sensory and gene regulation system named PhoP/PhoQ protects invading bacteria, and scientists believe if they develop a better understanding of this system they could develop new drugs that are more effective at protecting people from infection. Likewise, now Dr. Otto and his research group are hoping for ...

Researchers identify protein pathway involved in Parkinson disease development

...ound that the mitochondrial protein PINK1 normally protects cells from oxidative stress and promotes cell survival by regulating function of the protein TRAP1. When PINK1 is mutated, however, the protective TRAP1 pathway is disrupted, leading to mitochondrial damage. Other scientists recently have linked ...

Researchers develop buckyballs to fight allergy

... be the basis of aging. “The immune system both protects us and causes harm, so we are always interested in finding new pathways to help manage the harmful effects,” said Kepley....

New vaccine prevents CMV infection and disease in mice

...he mouse vaccine generates an immune response that protects against both infection and development of disease when the virus is present by completely disarming the virus’s ability to replicate and establish a persistent infection. The work is currently online in advance of publication in the July issue of Jo...

New study suggests potential for a broadly-protective HIV vaccine

... that it may be possible to develop a vaccine that protects against the myriad strains of the HIV virus. HIV is extremely variable, so an effective vaccine may need to stimulate the body to produce cross-reactive antibodies that will neutralize multiple viral strains. These results demonstrate that induction ...

Molecule that destroys bone also protects it, new research shows

...une diseases such as rheumatoid arthritis actually protects bone in the oral cavity from infectious pathogens ...action in rheumatoid arthritis(RA), IL-17 actually protects bone in the oral cavity from infectious pathogens such as Porphyromonas gingivalis, a bacterium that...

Hepatitis E takes a piggyback

...n their first 30 days, because a maternal antibody protects them. Vaccines are currently under development against HEV, although Satou and Nishiura suggest that changes in husbandry practices and avoiding eating raw liver might be more cost-effective measures should HEV’s hold on pig farms weaken....

Jefferson scientists find rabies-based vaccine could be effective against HIV

...oss of CD4 cells. "We still need a vaccine that protects from HIV infection, but protecting against developing disease can be a very important step," Dr. Schnell says, noting that he and his colleagues aren’t sure how long the viral immunity will last. According to Dr. Schnell, the study demonstrated a ...

New details on how the immune system recognizes influenza

...or vaccines are a major component of immunity that protects against these viruses. Strains of influenza virus can vary enough in their neutralizing B cell epitopes that a vaccine against one strain may not protect against another strain. But if epitopes are conserved between virus strains, the immunity a ...

'Guardian of the genome' protein found to underlie skin tanning

...rocess." There is even the possibility that p53 protects against skin damage in a second ?and previously unsuspected ?way. The protein not only causes skin to tan in response to sunlight, it may also underlie people's desire to spend time in the sun. The same process that causes POMC to produce alpha-MS...

Why doesn't the immune system attack the small intestine?

...bsorbs essential nutrients from food and drink and protects the body from invasive microbes, is literally teeming with bacteria, which help break down waste. The presence of so many bacteria is a potential trigger for an immune system response. Why do T cells almost always ignore the small intestine, leaving ...

Tumor-suppressor gene is critical for placenta development

...first tumor-suppressor gene, a class of genes that protects cells from becoming cancerous. It has since been shown to be inactivated in many cancers. In this study, researchers shut off the Rb gene in stem cells that give rise to most of the placenta, resulting in an abnormal placenta and death of the embr...

Ebola outbreaks killing thousands of gorillas and chimpanzees

...orilla does not protect only that gorilla, it also protects gorillas further down the transmission chain," said Peter Walsh of the Max Planck Institute for Evolutionary Anthropology, the lead author on the study. "Thus, protecting remaining ape populations may not require vaccinating a high proportion of indi...

Destructive enzyme shows a benevolent side

...ular and Cellular Biology. "The stress response protects cells from these conditions by sequestering mRNAs ...cay suggests that something in the stress response protects these mRNAs from being degraded, even though the degrading enzyme PMR1 is there in the stress granul...

What recognizes what in plant disease resistance?

...encodes a protein that specifically recognizes and protects against one pathogen or strain of a pathogen carrying a corresponding Avirulence (Avr) gene. In tobacco and its relatives, the N resistance protein confers resistance to infection by the Tobacco mosaic virus (TMV). The authors used N, and the TMV ...

Mosquito repellents that emit high-pitched sounds don't prevent bites

... they emit repels female mosquitoes, and therefore protects people in the vicinity from bites and disease. To test these claims a team of Cochrane Researchers conducted a systematic review looking for trials conducted with EMRs. They located ten field trials that had been carried out in various parts of th...

Researchers uncover protection mechanism of radiation-resistant bacterium

...remely resilient bacterium Deinococcus radiodurans protects itself from high doses of ionizing radiation (IR). The results of the recent study, titled "Protein Oxidation Implicated as the Primary Determinant of Bacterial Radioresistance" were published in the March 20 edition of PLoS Biology. These discoveri...

Protein found to shield pancreatic cancer cells from self-destruction

An overexpressed protein protects human pancreatic cancer cells from being forced to devour themselves, removing one of the body's natural defenses against out-of-control cell growth, researchers at The University of Texas M. D. Anderson Cancer Center report in the March issue of Mol...

Knocking out survival protein could aid leukemia treatment

...emia might be to knock out a specific protein that protects cancer cells from dying, a new study shows. The findings suggest that a drug that can block this "survival protein" might on its own be an effective therapy. But such a drug used in combination with several existing drugs might also offer an ef...

Key found to kill cystic fibrosis superbug

...chers has identified a weakness in the armour that protects the B. cenocepacia bacterium from the effects of antibiotics. They hypothesize that preventing the synthesis of a key sugar required for this armour, 4-amino-4-deoxy-L-arabinose (Ara4N), may lead to a susceptibility within the cell membrane to antibi...

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