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Tag: "protective" at biology news

Topical treatment shown to inhibit HIV and herpes simplex virus infection

...ially increase susceptibility to HIV and limit any protective effect of microbicides." said Betsy Herold, M.D., Professor of Medicine and Chief of Pediatric Infectious Disease at Mount Sinai and the senior investigator on this study. "We are currently conducting a 14-day study to assess whether or not there is ...

Scientists Replicate Hepatitis C Virus in Laboratory

... virus, and did not have the HCV viral envelope, a protective shell of lipids and proteins that surrounds the viral RNA in fully-formed HCV. The naked HCV construct was then placed into human liver cells in a cell culture medium. The NIDDK scientists found evidence of HCV proteins and HCV RNA within the human ...

Computers to be used to find blueprint for new influenza drug

...rk by being chemically very similar to part of the protective coating around the cells in our throats that the flu virus first attacks when a person becomes infected. The flu virus would be deceived into attacking the drug, called an inhibitor, instead of the cells. The three-year project will be largely carri...

Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates

...ctedby Parkinson disease and is reported to have a protective effect on DAneurons. The authors observed increased DA neuron development andsubsequently transplanted these neurons into monkeys treated with anagent called MPTP, which is considered a primate model for Parkinsondisease. These transplanted cells wer...

NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis

...esearchers found that neurons are sensitive to the protective effect of interferons, inducing pathways to fight the virus' spread. However, their findings showed that interferons fight the virus at different stages of the virus' life cycle. First, they inhibit viral RNA and protein synthesis. If this fails, int...

New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines

...oy. The Duke team discovered that certain broadly protective antibodies, which recognize and latch onto the HIV...e failed in part because certain proteins on HIV's protective outer coat trigger only short-lived, self-reactive antibodies instead of long-lasting, HIV-specific ...

NYU study reveals how brain's immune system fights viral encephalitis

...esearchers found that neurons are sensitive to the protective effect of interferons, inducing pathways to fight the virus' spread. However, their findings showed that interferons fight the virus at different stages of the virus' life cycle. First, they inhibit viral RNA and protein synthesis. If this fails, int...

Substance protects resilient staph bacteria

...ute to evading human immune defenses. Biofilms are protective cell-surface structures. Biofilm formation does not depend on PGA, but other research in Dr. Otto's laboratory has indicated that PGA production is greater when a biofilm is present. Further, Dr. Otto says all 74 strains of S. epidermidis that his gr...

PGA on a tour under the skin

... which the organism becomes so pathogenic once the protective barrier of the skin is removed remains unclear. In their study appearing online on February 3 in advance of publication in the March 1 print edition of the Journal of Clinical Investigation,.Michael Otto and colleagues from Rocky Mountain Laboratori...

Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries

...pathology, and his colleagues first discovered the protective role of AIM six years ago. In the current study, scientists exposed mice lacking AIM to a fatty diet that would normally induce atherosclerosis. After several weeks, researchers found little to no atherosclerotic lesions. Comparatively, in mice that...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

...variant Creutzfeld-Jakob." He says there "must be protective mechanisms working there, but we don't know what they are." The other members of the Weissman research team include Motomasa Tanaka and Peter Chien. The Weissman study was supported by Howard Hughes Medical Institute, The David and Lucile Packard Fo...

Scientists discover how plants disarm the toxic effects of excessive sunlight

...singlet oxygen. By modifying plants to enhance the protective pathway, "we could be able to get larger crop yield per photon of light," he says. And by making cells more resistant to singlet oxygen, scientists may be better able to design bioenergy systems that use sunlight as an alternative to traditional fos...

Marburg haemorrhagic fever in Angola update

...close contacts, infection control in hospitals and protective clothing for staff work to interrupt chains of tra...ties, staff from the mobile teams, fully suited in protective gear, are seen as taking away relatives and loved ones who may never again be seen alive. WHO staff...

First frozen egg baby born in Canada

...ed from the ovaries of the patient is drawn into a protective device, invented by Drs. Chian and Tan, called a "Cryoleaf", and then placed in a special vitrification solution. The eggs undergo super-rapid cooling at a rate of more than 20,000ºC per minute, which prevents ice crystal formation and increases egg ...

Leprosy microbes lead scientists to immune discovery

...arch gives us insights about how the body develops protective immunity against bugs that invade our cells--or fails to. Now we know the players, and we would love to look at them in other diseases such as tuberculosis in the lungs and juvenile diabetes." Harvard School of Public Health is dedicated to advancin...

Global analysis of membrane proteins

All cells are encased within a protective lipid membrane. The membrane is studded with many hundreds of different proteins that transport nutrients, ions, and water into and out of the cell. Such membrane proteins also help cells recognize each other in the body, and make the nervous system ...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

...d siRNA into nanoparticles that, in effect, form a protective shield around their precious genetic cargo. These nanoparticles, in turn, are attached to transferrin, a protein that typically carries iron molecules through the bloodstream until it meets up with a transferrin receptor on the surface of another cel...

Chromosome Deletion Predicts Aggressive Neuroblastoma

...ss of material at that site apparently removes the protective effect of a tumor suppressor gene, and thereby allows the tumor to grow. Patients in the study with the chromosome deletion had a three-year overall survival rate of 66 percent, compared to 83 percent for patients without the deletion. Dr. Attiyeh's...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

...eces of DNA on the ends of chromosomes that act as protective caps -- allowing DNA ends to be copied completely when cells are replicated. This is the first major piece of telomerase for which the structure is known. Telomerase plays a key role in most cancers, and this work ultimately may lead to targets for ...

Plant Sacrifices Cells to Fight Invaders

...ammed cell death (PCD). Plants use PCD to create a protective zone of dead cells around the infection site to prevent the invading pathogen from spreading. But how the plants keep from killing themselves after they turn on the cell-suicide process was a mystery. Now, in the May 20 issue of the journal Cell, Ya...

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