Bound for destruction: Ubiquitination protects against improper Notch signaling
...ptors that have not been activated by a ligand are protected fromdigestion by that protease. Now, in a report published in the December29 issue of Current Biology, Shigeo Hayashi (Group Director, Laboratoryfor Morphogenetic Signaling) and colleagues at the RIKEN Center forDevelopmental Biology (Kobe, Japan) ha...Female sex hormones play a vital role in defense against sexually transmitted diseases
...dies can figure out that women too, like mice, are protected in primary exposure by estradiol, contraceptive cr...ound in the body. The estradiol-treated mice were protected 100 percent, whereas the progesterone-treated mice and mice that didn't receive any hormones, showed...Enzyme shown to help protect genomic stability
...closed, unavailable for transcription and possibly protected from dangerous genetic recombinations with other regions of the genome. A report on the research, which was conducted in yeast, appears in the February 18 issue of Molecular Cell. "There are regions of the genome that have to be inaccessible," says ...Experiments provide proof of how traveling in groups protects insects
...urs anyway, but any given individual is far better protected than it would be if it were on its own." The research, supported by the USDA, is part of a larger study designed to learn whether scientists can predict and possibly change the path of massive insect bands, he said. "In the United States nowadays, ...Experiments provide proof of how traveling in groups protects insects
...urs anyway, but any given individual is far better protected than it would be if it were on its own." The research, supported by the USDA, is part of a larger study designed to learn whether scientists can predict and possibly change the path of massive insect bands, he said. "In the United States nowadays, ...Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
...Research,on Nov. 29, 2004, showed that the vaccine protected 86 percent ofexperimental mice against HER2/neu-as..., 86 percent of mice thatreceived the vaccine were protected against the cancer. The experimentwas repeated numerous times with the same result, says Lachman.Res...A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020
...Research,on Nov. 29, 2004, showed that the vaccine protected 86 percent ofexperimental mice against HER2/neu-as..., 86 percent of mice thatreceived the vaccine were protected against the cancer. The experimentwas repeated numerous times with the same result, says Lachman.Res...Study of genomic DNA leads to new advances in cancer diagnostics
...esults suggest that a cell's DNA, or chromatin, is protected during malignancy. This effect was confirmed using three pairs of cell types (normal melanocytes and melanoma cells, normal breast epithelium and breast carcinoma cells, and normal fibroblasts and fibrosarcoma cells) and diagnostic biopsy samples. W...Photos show jaguar vamping for camera
... the park, which may contain more jaguars than any protected area in Latin America. Normally the cameras, which are tripped by an infrared beam, capture little more than a fleeting glimpse of wildlife. No one knows why this particular jaguar spent so much time in front of the camera, where it alternatively sa...Biodiversity hotspots identify conservation priorities
...s recent pledge to triple the size of his nation's protected area network. "The new hotspots analysis ensures that we will continue to direct conservation funds to the areas where we can have the greatest possible impact," said Peter Seligmann, CEO and chairman of the board of CI. "It also points out the need...WHO Warns Of Increased Risk Of Vector-borne Diseases In Tsunami-affected Areas
...situations and support the communities so they are protected from disease, and have access to treatment when they need it". "To reduce the risk of a dengue fever or malaria cases, WHO is strengthening its support to national authorities to implement effective vector-borne disease prevention and control activi...Promising new West Nile therapy cures disease in mice
... Emerging Infectious Diseases. "It also completely protected the mice against death." The researchers decided to develop the potential treatment--known as a monoclonal antibody--after finding that antibodies taken from the blood of people who recovered from West Nile fever could cure mice infected with West N...Measles Deaths Worldwide Drop By Nearly 40% Over Five Years
...r of losing their children to measles, they're now protected by an effective and inexpensive vaccine," said Carol Bellamy, Executive Director of UNICEF. "What clearer proof could there be of the value of investing in immunization?" The dramatic decline in measles deaths is made possible through the commitment...New strategies to reduce hospital-aquired infections
... problem, some of these harmful pathogens are also protected by amoeba that are resistant to chlorination, temp... and success in Europe to ensure that patients are protected from dangerous waterborne pathogens. Health and government agencies continue to stress the need for...Distributed Basic Local Alignment Search Toolkit (W.ND-BLAST)
... problem, some of these harmful pathogens are also protected by amoeba that are resistant to chlorination, temp... and success in Europe to ensure that patients are protected from dangerous waterborne pathogens. Health and government agencies continue to stress the need for...Wake Forest scientists find new combination vaccine effective against plague
...id. He said the research shows that the mice were protected for at least three months after immunization. The... Mizel plans to determine if immunized monkeys are protected against the plague. If they are then efforts will be initiated to begin studies in humans. ...New vaccine means bye-bye to bacteria in the lung
... with this vaccine induced antibody production and protected the mice from exposure to a deadly dose of the bacteria. Importantly, the mice could be repeatedly given the vaccine and the immune response against P. aeruginosa was boosted. Usually, adenovirus vectors do not allow for repeated infection. These re...Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine
...over six weeks with rV10 developed antibodies that protected them from many times the lethal dose of the bacteria. "Our data, the authors conclude, "provide the first evidence of plague vaccines that do not suppress innate immune responses ?and that may be useful for plague vaccination in animals, and, perhap...Scientists discover global pattern of big fish diversity in open oceans
...high seas diversity. "The high seas are the least protected places on this planet ?a region where legal and pirate fishers rub shoulders in the pursuit of big fish and even bigger profits," says Callum Roberts of the University of York in the United Kingdom. "Conservationists are fighting to place some areas ......that a single treatment with a DNA-binding protein protected against nerve damage that in humans can lead to limb loss." The results of the pre-clinical studies were recently presented to the American Diabetes Association in California and the first phase of clinical trials has now begun. An estimated 50 per...