Navigation Links

Tag: "proteasome" at biology news

Compound from marine bacteria shows potential as multiple myeloma therapy

...r cells' proteasomes from working effectively. The proteasome work as a cell's "garbage disposal," chewing up and disposing of old, unwanted proteins. With their proteasome jammed, cells die from the backup of damaged proteins. "Proteasome inhibition is a key therapeutic ...

MIT research holds promise for Huntington's treatment

...mpound also had a strong protective effect against proteasome disruption, thus blocking one of the toxic effects of the huntingtin protein. The B2 compound also promoted large inclusions and showed a protective effect in a cellular model of Parkinson's disease, another neurodegenerative disorder caused by misf...

Johns Hopkins lab scientists tame overactive CF protein

... latches onto the damaged CFTR and sends it to the proteasome for destruction," Zeitlin says. "Using RNA interfe...by the use of RNA interference was superior to the proteasome inhibitor, researchers found. Both the drug and RNA interference also staved off inflammation cause...

Brain enzyme treatment relieves memory lapse in Alzheimer's mice

...th Alzheimer's after death found evidence that the proteasome remained intact but largely unable to degrade prot... cascade that results in the partial inhibition of proteasome activity more rapidly than is likely as the result of the accumulation of misfolded or undigestable ...

Study reveals how cells destroy faulty proteins in cystic fibrosis

...asome. This trash system is known as the ubiquitin proteasome pathway. "We've identified the trash collectors that recognize misfolded proteins, decide if they might be toxic to the cell and mark them with ubiquitin. The ubiquitinated proteins, including faulty CFTR, are then degraded or shredded by the pro...

MIT finds most complex protein knot ever seen

...rolase may prevent it from getting sucked into the proteasome as it works, Mirny said. The researchers hypothesi...oteins with complex knots can't be pulled into the proteasome as easily, and the knots may make it harder for the protein to unfold, which is necessary for degrad...

Researchers wake up viruses inside tumors to image and then destroy cancers

... both surprised and lucky," he says. "Velcade is a proteasome inhibitor, but it also induces the lytic cycle thereby activating the TK in the Epstein-Barr virus. Once the TK is activated, we can image the tumors." To test their findings, the researchers used mice carrying human Burkitt's lymphoma, a cancer ...

Proteasome activator enhances survival of Huntington's disease neuronal model cells

...such protein build up in the cell is the ubiquitin proteasome system (UPS). In Huntington's disease (HD) brains...al proteins in HD. We first genetically engineered proteasome activators involved in either non-ubiquitinated protein degradation pathways (PA28ƒ×) or subunits of...

Penn researchers link cell's protein recycling systems

...aylor and his group study fruit flies in which the proteasome is disabled by a genetic mutation, which results i...w that this system can compensate for the impaired proteasome function, which in itself tells us that the two pathways intersect,” says Taylor. “The question was,...

1

Other Tags
(Date:6/25/2015)... According to a new ... Area), Technology, Material (Optical Prism, Piezoelectric, Capacitive & ... Others) & Geography - Global Forecast to 2014 ... is expected to reach $14,500.07 Million by 2020, ... Browse 76 market Tables and 109 Figures spread ...
(Date:6/24/2015)... SAN JOSE, Calif. , June 24, 2015 ... leading developer of human interface solutions, today announced ... fingerprint sensor to provide secure authentication for its ... Having recently reached more than 200 million shipments ... shipment with Sharp reinforces Synaptics, strength, scalability and ...
(Date:6/23/2015)... 2015   Valencell, a leader in ... a recent study that illustrates its PerformTek biometric ... activity. In a study conducted at Valencell,s Biometric ... the Apple Watch against a chest strap – ... activity. The study demonstrated that Valencell,s biometric technology ...
Breaking Biology News(10 mins):Fingerprint Sensors Market Worth $14,500.07 Million by 2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 4Synaptics Brings Natural ID Technology to Sharp's Newest Flagship Smartphone 2Valencell Delivers Breakthrough Heart Rate Accuracy on the Wrist 2Valencell Delivers Breakthrough Heart Rate Accuracy on the Wrist 3
(Date:7/4/2015)... New York, NY (PRWEB) , ... July 04, 2015 , ... When a hacker gains ... the home front and at the office. On Wednesday, July 1st, the FTC issued ... their credentials as part of a verification process for a password reset instigated by the ...
(Date:7/3/2015)... ... ... The Harvest Hope Food Bank will hopefully be getting a large donation of ... the area of Greenville SC are making it their mission to collect as many canned ... asking for donations from the public as well. As part of the canned food drive, ...
(Date:7/3/2015)... ... July 03, 2015 , ... ... opened registration for a new SEO training system called "Page One Engine" ... organic traffic generation has received glowing reviews from several well-known marketers. HonestyFirstReviews.com's Tiffany ...
(Date:7/3/2015)... ... ... Scientists at several top US cancer centers believe they now know why ... here to read the complete story , just posted on the Surviving Mesothelioma website. ... and New York University exposed mice with a mutation on the tumor suppressor gene ...
(Date:7/3/2015)... ... 03, 2015 , ... B. E. Smith, the only full-service ... a national president recruitment for Regional Care, Inc. in Scottsbluff, Neb. ... Smith has recently placed more than 1,000 healthcare executives into organizations. , ...
Breaking Medicine News(10 mins):Health News:New FTC Scam Alert Shows Latest Example of Social Engineering Dangers 2Health News:New FTC Scam Alert Shows Latest Example of Social Engineering Dangers 3Health News:New FTC Scam Alert Shows Latest Example of Social Engineering Dangers 4Health News:Greenville Area AlignLife Offices to do a Thanksgiving in July Food Drive 2Health News:Greenville Area AlignLife Offices to do a Thanksgiving in July Food Drive 3Health News:Page One Engine - Review Of Dori Friend's SEO Training Course Released 2Health News:Study Finds Small Amounts of Asbestos May Trigger Mesothelioma in People with Genetic Mutation, According to Surviving Mesothelioma 2Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 2Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 3
Other Contents