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Tag: "prostate" at biology news

Study: Harmless virus kills some cancers

...on-disease-causing virus to kill cervical, breast, prostate and squamous cell cancer cells in laboratory cultu...pproach in four types of cancer ?cervical, breast, prostate and squamous cell - all epithelial cell cancers. Epithelial cells are those that cover or line all o...

First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology

... an equal ability to be internalized by antigen on prostate cancer cells. At the same time, chicken-produced antibodies lacked the sugar residue, fucose, which greatly increases their cell-killing activity compared to CHO-produced antibodies." To create the antibody-producing chickens, the researchers first ...

UCLA cancer researchers shake loose hidden biomarker

... a way to move an important biomarker expressed in prostate cancer, shaking it loose from one location in a ce...tant implications for using immunotherapy to treat prostate cancer, said Ayyappan K. Rajasekaran, a Jonsson Cancer Center researcher and senior author of the ar...

Tamoxifen-like drug suggests new ways to selectively block estrogen

...eene said. "We could create designer androgens for prostate cancer, or designer glucocorticoids to treat inflammation." Since "the primary regulator of cofactor recruitment is receptor conformation," added study co-author Donald McDonnell of Duke, findings such as this should lead to the emergence of "a new ...

Chemists synthesize molecule that helps body battle cancers, malaria

...s melanoma, breast cancer, small-cell lung cancer, prostate cancer, HIV-1 and malaria. An extract from the bark of the South American tree Quillaja saponaria Molina, QS-21A is available only in small quantities. "Now that we have synthesized this remarkable molecule and confirmed its structure, we are in a p...

Researchers find promising cancer-fighting power of synthetic cell-signaling molecule

...s found that Enigmols suppress the growth of human prostate tumors implanted in mice, which is a commonly used model to test new anti-cancer drugs. They were also effective in two other mouse models for colon cancer. "We do not know why Enigmols affect such a wide range of tumor cell types," Merrill said. "B...

Test for early detection of prostate cancer shows promise

...nical study of a new blood protein associated with prostate cancer, researchers have found that the marker, called EPCA or early prostate cancer antigen, can successfully detect prostate cancer in its earliest stages. At the same time, th...

Nanoscale Diagnostic Sets Sights on Alzheimer's

... already experimented with biomarkers for AIDS and prostate cancer. This research was supported by both NSF's Engineering Research Centers program and the NSF Office on International Science and Engineering. Comments from the researchers: "This study is a major step forward in identifying a routine diagnos...

Estrogen-like Component of Plastic Stimulates Growth of Certain Prostate Cancer Cells

...n toencourage the growth of a specific category of prostate cancer cell,potentially affecting the treatment ef...hed in the January 1 issue of CancerResearch, such prostate cancer cells proved to be vulnerable toexposure to the chemical BPA (bisophenol A), an industrial ch...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...l work just as well at inhibiting the migration of prostate and colon cancer cells," said senior researcher Dr. Xin-Yun Huang, Professor of Physiology and Biophysics at Weill Cornell Medical College in New York City. The findings have just been published in Proceedings of the National Academy of Sciences. F...

Researchers identify target for cancer drugs

...cells that contributes to many malignant brain and prostate cancers. While scientists have identified elements of this pathway, other key components have remained a mystery. Researchers at Whitehead Institute now have discovered a missing puzzle piece, a finding that may present drug makers with a significant...

Mitochondrial DNA mutations play significant role in prostate cancer

...mtDNA) playan important role in the development of prostate cancer, according toresearch by scientists at Emor...alifornia,Irvine, sequenced segments of mtDNA from prostate cancer patients andfound a variety of mutations, including various mutations in the mtDNAcytochrome ...

Imaging Lymph Nodes with Nanoparticles

...articles toassess lymphoid spread in patients with prostate cancer. Now, in apaper published in this month's PLoS Medicine, they have gone furtherby extending the analysis to patients with different types of cancer,and producing an algorithm that allows semiautomation of the procedure.The authors developed th...

Columbia research lifts major hurdle to gene therapy for cancer

...to a specially designedvirus. The virus eradicated prostate cancer cells in the lab and inanimals while leaving normal cells unscathed. Genetherapy based on the new technique should also be effective for a widerange of tumors - such as ovarian, breast, brain (glioma), skin(melanoma) and colon cancer - becaus...

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