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Tag: "prostate" at biology news

Experimental RNA-based drug kills prostate cancer cells effectively and safely

...ug -- the first of its kind -- tricks its way into prostate cancer cells and then springs into action to destr...hat keeps the cells alive. In tests in mice with prostate cancer, the drug shrank the size of their tumors by half, while the tumors in control mice that did ...

Selenium-protein deficiency raises prostate cancer risk

...lated mice were mated. One was prone to developing prostate cancer. The other had lower levels of selenoprotei...al model system of selenium-containing proteins to prostate cancer and, by extrapolation, the mechanism by which selenium prevents cancer," said Diamond. Furth...

New human retrovirus originated in mice

...scovered the virus in patients with a rare type of prostate cancer. The patients in the study have a genetic m...means implicate the virus, dubbed XMRV, in causing prostate cancer. The virus may well have flourished as a result of the failure of the defense mechanism; and ...

COX-2 inhibitors significantly reduce risk of cancer

...pes of cancer in the United States: breast, lung, prostate and colon cancer. NSAIDs are non-steroidal, anti-inflammatory drugs that block the COX-2 enzyme pathway that is often activated in inflammation, cancer, heart disease and other disorders. Harris and his colleagues studied the use of celecoxib (Cele...

Inflammation and drugs to control this activity studied in a variety of tumors sites

... have evidence linking chronic inflammation in the prostate to a greater risk of developing prostate cancer. Results of repeat biopsies of prostate tissue over a five-year period from men who had abnor...

AIDS-related cognitive impairment exists in two separate forms

...tly, physicians cannot predict which patients with prostate cancer should receive extra therapy after surgery ...es provides much needed prognostic information for prostate cancer patients who fall in the "gray zone" of traditional tests. This experimental "universal bead...

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

...tly, physicians cannot predict which patients with prostate cancer should receive extra therapy after surgery ...es provides much needed prognostic information for prostate cancer patients who fall in the "gray zone" of traditional tests. This experimental "universal bead...

Macrophage signaling may affect hormone resistance in prostate tumors

Interaction between prostate cancer cells and immune cells called macrophages m...nists, the most common and effective treatment for prostate cancer, according to a new study by researchers at the University of California, San Diego (UCSD) Sc...

UCLA scientists uncover mechanism of response to targeted therapy

...ge. CCI-779 had previously been tested at UCLA in prostate cancer patients and researchers knew it targeted the mTOR protein. Previous studies also had shown that inhibitors of mTOR also might inhibit HIF. "We theorized that by inhibiting mTOR, which contributes to HIF levels, we might be able to significa...

Basic research leads to a novel cancer therapy

...ncer, melanoma, ovarian cancer, pancreatic cancer, prostate cancer, and testicular cancer. The studies are in various stages of clinical trials (phases I through III), and most of them are being carried out in combination with other therapies. Ullrich is very pleased with the quick approval of SUTENT®. He sa...

Curry and cauliflower could halt prostate cancer

...real potential for the treatment and prevention of prostate cancer, particularly when combined with certain ve...urcumin could be effective in treating established prostate cancers," said Ah-Ng Tony Kong, a professor of pharmaceutics at Rutgers, The State University of New...

New compound protects against liver cancer

...strong link to inflammation, such as liver, colon, prostate and gastric cancers. It could also play a role in preventing diseases such as neurodegeneration, asthma and emphysema. The findings are featured in the February 15, 2006, issue of the journal Cancer Research. CDDO-Im is a synthetic compound that bel...

New hybrid virus provides targeted molecular imaging of cancer

...mouse models of common diseases such as breast and prostate cancer." Their next step was to work closely with the team of M. D. Anderson researcher Juri Gelovani, M.D., Ph.D., chair of the Department of Experimental Diagnostic Imaging, a pioneer in development of molecular-genetic imaging tools. "We could s...

Human prostate grown from embryonic stem cells

In a giant step towards understanding prostate disease, Melbourne scientists have grown a human prostate from embryonic stem cells. A study published in the March edition of Nature Methods describes how h...

'Virus chip' detects new virus in prostate tumors

...ic scientists have discovered a new virus in human prostate tumors. The type of virus, closely related to viru...SARS virus three years ago. While the genetics of prostate cancer are complex, one of the first genes implicated in the disease was RNASEL, a gene that serves ...

Researchers use 'trickery' to create immune response against melanoma

...slow release over a period of several years. Using prostate cancer as a model disease, proof of concept nanosc...1 nanometer = 0.000000001 meter), which can target prostate cancer cells with high specificity and efficiency. Once bound to prostate cancer cells, the nanopart...

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

...slow release over a period of several years. Using prostate cancer as a model disease, proof of concept nanosc...1 nanometer = 0.000000001 meter), which can target prostate cancer cells with high specificity and efficiency. Once bound to prostate cancer cells, the nanopart...

The nude mouse tale: Omega-3 fats save the life of a terminal cancer patient

...essed the growth of human mammary, ovarian, colon, prostate and pancreatic cancer cells that were injected int...that Inuit Eskimo populations have less breast and prostate cancer deaths. So far, though, most studies in this country are limited to animal models, but a case...

Genes involved in biofilms

...ues involving infections of the middle ear, of the prostate gland, pneumonia in patients with cystic fibrosis, osteomyelitis, etc. In the interior of the biofilm, bacteria present greater resistance to antibiotics, to the opsonisation by antibodies and to phagocytosis, which explains the chronic character o...

Cancer support cells may evolve, fuel tumor growth, study shows

...s involved a genetically engineered mouse model of prostate cancer developed in Van Dyke's UNC laboratory. The...pulated epithelial cells ?the target cell type for prostate cancer ?causing them to divide at an accelerated rate. First, they found that this accelerated divi...

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