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Tag: "prostate" at biology news

Firefighters face increased risk for certain cancers

...icantly higher rates of non-Hodgkin's lymphoma and prostate cancer than non-firefighters. The researchers also confirmed previous findings that firefighters are at greater risk for multiple myeloma. Grace LeMasters, PhD, Ash Genaidy, PhD, and James Lockey, MD, report these findings in the November edition ...

Computer scientists unravel 'language of surgery'

...mally invasive procedures involving the heart, the prostate and other organs. Although only a tiny fraction of hospital operations involve the da Vinci, the device's value to Hager's team is that all of the robot's surgical movements can be digitally recorded and processed. In a paper presented at th...

Scientists explore how complex organs develop from a simple bud

...on. An investigation into the morphogenesis of the prostate gland and seminal vesicles is included, as well as an in-depth look at the genetic and cellular interactions critical to placental development. Research on this process in mouse kidneys generated a real-time tracking procedure which has significant i...

Mayo discovers protein as potential tactic to prevent tumors

... Ph.D., co-leader of the Mayo Clinic Cancer Center prostate cancer research program. "CDK2 is a key protein component in the cellular mechanism that leads to repair of damaged DNA." If cells pass this quality control checkpoint, they can resume the process of dividing into two daughter cells. If, however, ...

'Trojan Horse' agent halts bone metastasis in mice

...bility of VEGF121/rGel to halt the growth of human prostate cancer cells in the bones of mice, investigators s...s. In this study, investigators implanted human prostate cancer cells, which are highly metastatic to bone, directly into the leg bone marrow of experimental...

Older men treated for early prostate cancer live longer than those who are not

... who received treatment for early stage, localized prostate cancer lived significantly longer than men who did...sed with early-stage and low-or intermediate-grade prostate cancer. Studies have shown that the slow-developing nature of prostate cancer during its earliest st...

Exposure to dioxins influences male reproductive system, study of Vietnam veterans concludes

... reproductive health by limiting the growth of the prostate gland and lowering testosterone levels, researcher...that there is a link between dioxins and the human prostate leading us to speculate that dioxins might be decreasing the growth of the prostate in humans like t...

Gene chip technology shows potential for identifying life-threatening blood infection

...eater than deaths from breast, colon, pancreas and prostate cancer combined. Currently, a diagnosis of sepsis or non-infectious systemic inflammation is made by sending cultures of patients' blood, sputum, or urine to the laboratory for analysis, which can take several days. Gene chips could cut the typica...

Jefferson scientists find aging gene also protects against prostate cancer development

...e that is involved in regulating aging also blocks prostate cancer cell growth. The researchers, led by Kimmel...ill aid in better understanding the development of prostate cancer and lead to new drugs against the disease. SIRT1 is a member of a family of enzymes called ...

New path from estrogen to survival in breast cancer cells described

...ntly found to be over-expressed in both breast and prostate cancers. Yeh and his team show that this protein, by itself, doesn't have any relationship to the cancer, but when modified by the protein NEDD8, can act like a tumor suppressor. The researchers also found that SIRT1, a key protein involved in this...

Gene therapy study takes aim at prostate cancer

... that takes a gene called RTVP-1 directly into the prostate tumor will prove effective in preventing recurrenc... is simple, said Kadmon. "One injection into the prostate that should take no more than 10 minutes, although patients will be monitored in a special unit of t...

Targeted virus compels cancer cells to eat themselves

...owed in lab experiments that the virus kills human prostate and human cervical cancer cells while sparing normal tissue. In addition to demonstrating the therapeutic potential of the virus, called hTERT-Ad, Kondo says the international research team also clarified the mechanism by which such conditionally ...

Genetic 'roadmap' charts links between drugs and human disease

...e mechanisms underlying a novel drug candidate for prostate cancer, and that a drug currently used to treat on...reen for molecules that disrupt hormone signals in prostate cancer cells and then used the Connectivity Map to help uncover its precise molecular action. As con...

Scientists use gene signatures to match cancer and other diseases with potentially effective drugs

...therapies for drug-resistant leukemia and advanced prostate cancer. Scott Armstrong, MD, PhD, a pediatric on...d gedunin, with a mechanism by which some advanced prostate tumors continue to grow aggressively despite hormone-blocking treatments. A paper in Cancer Cell rep...

Major cancer study aims to identify protein markers for early-stage disease

...dy being applied in the clinic: Elevated levels of prostate specific antigen (PSA) hint at the presence of prostate cancer, while elevated levels of cancer antigen 125 (CA-125) suggest possible cancer of the ovary or...

Gene discovery opens door to tackling disease

...ene that could lead to breakthroughs in breast and prostate cancer, as well as diabetes. The gene, called SLI...strogen in breast cancer cells and testosterone in prostate cancer cells. "Most of those cancers depend on the hormones to stay alive, so if we can use SLIRP t...

Lack of key enzyme associated with development of rare tumor

...drenal glands and in even larger amounts in normal prostate glands, Dr. Stratakis added. Other forms of PDE11A are found in several other tissues, including the testes, skeletal muscle, and the heart. Dr. Stratakis noted that although the evidence associating the mutation in the gene for PDE11A to the devel...

New research: Soy germ isoflavones reduce bone loss

...promote women's health, bone health, heart health, prostate health and cognitive function. A focus of the study, SoyLife® is a range of ingredients from soy germ, rich in isoflavones. More than just an isoflavone concentrate, SoyLife® offers the complete spectrum of natural soy compounds, the Soy Matrix TM ,...

3-D model reveals secrets of metastasis

...hree dimensions. His study, which focused on human prostate tumor cells, appeared this week in the online early edition of Proceedings of the National Academy of Sciences. "Two-dimensional assays ignore the obstacles that cells face in their natural contexts," explains Zaman, who recently became an assistan...

First-ever genomic test predicts which lung cancer patients need chemotherapy to live

...er now kills more Americans each year than breast, prostate and colorectal cancers combined. But toxic chemotherapy drugs are prescribed only to patients with relatively large and aggressive tumors. Early-stage patients ?those with small, stationary tumors ?are considered at low risk of recurrence. Hence, t...

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