Yale researchers find environmental toxins disruptive to hearing in mammals
...sing TBT on isolated cells only, Santos-Sacchi had proposed that the ear's ability to perceive sound would be compromised. He also speculated that whales and other marine mammals exposed to TBT would have altered sound localization abilities. The present findings confirm that their hearing is altered in mamma...New insight into machinery of immune cells' 'tentacles'
... WASp can still form immunological synapses, so we proposed that there was another unidentified pathway that regulated the process." In their experiments, the researchers concentrated on a protein called "Abl interactor" (Abi), which had been identified earlier in the Pendergast laboratory. The earlier resea...Major WHO study concludes calcium supplements can reduce complications during pregnancy
...is to test in a second round of simulations -- the proposed mechanics of the protease enzyme's nanomachinery--he used artificial restraints in the computer program to block the flaps from opening by expanding the gap between "ear" and "cheek." A new type of drug that binds there and controls flap motion could...Computer simulation hints at new HIV drug target
...is to test in a second round of simulations -- the proposed mechanics of the protease enzyme's nanomachinery--he used artificial restraints in the computer program to block the flaps from opening by expanding the gap between "ear" and "cheek." A new type of drug that binds there and controls flap motion could...Two NIH initiatives launch intensive efforts to find roots of common diseases
...tic variations and result in human diseases. The proposed federal funding level will enable GEI to perform genetic analysis ?or genotyping - studies for several dozen common diseases. The exact diseases to be studied will be determined by peer review. An initial survey of existing NIH-supported clinical stu...High resolution 'snapshots' detail dynamics of a cocaine antibody
... show some promise. Immunopharmacotherapy has been proposed as a way to neutralize the drug outside the central nervous system- basically soaking up the drug before it has a chance to cross the blood brain barrier-as a potentially effective new approach to treat cocaine abuse." Using a monoclonal antibody en...Less antibiotic use in food animals leads to less drug resistance in people, study shows
...es' success. The U.S. Food and Drug Administration proposed banning fluoroquinolones in poultry in 2000, but one drugmaker fought the ban until it was finally enacted in September 2005. Reducing the use of antibiotics in food animals, coupled with the authors' additional recommendation of "sensible use of f...Researchers unravel DNA tangles and enzyme seamstresses
... Baylor College of Medicine in Houston, Texas, who proposed the notion in an earlier conceptual report, and the lead author, Zhirong Liu, is a U of T postdoctoral fellow in Chan's research group. "These are the same general principles that can be applied to other areas of science and engineering to address va...Animal brains 'hard-wired' to recognize predator's foot movements, Queen's study suggests
...that don't fit the ballistic movement pattern of a proposed 'life detector'," he says. "Snakes, insects and spiders, or birds can generate pathological reactions not observed in response to 'normal' animals." ...Researchers test new way to quit smoking
...otine is a highly addictive substance. It has been proposed that the stress a person undergoes when giving up cigarettes, coupled with the burden of remembering to use alternative methods of nicotine delivery, is too much too soon. "If a person first becomes used to the patch or gum, it might make the transi...Forsyth scientists gain greater understanding of how embryos differentiate left from right
...ion transporter. Based on these observations, they proposed a detailed pH- and Vmem-dependent model of the early physiology of left/right patterning. Michael Levin, PhD. is an Associate Member of the Staff in The Forsyth Institute Department of Cytokine Biology and the Director of the Forsyth Center for Rege...Scientists discover basic defect in cystic fibrosis airway glands
...eabsorbed by other channels. In fact, it has been proposed that one of CFTR's functions is to inhibit the activity of a channel called the epithelial Na+ channel (ENaC). Nam Soo Joo and colleagues at Stanford University attempted to determine which hypothesis was correct by measuring the secretion from glan...Warbling whales speak a language all their own
... songs are hierarchical, confirming a theory first proposed by biologists Roger Payne and Scott McVay in 1971. Suzuki said that information theory also enabled the researchers to determine how much information can be conveyed in a whale song. Despite the "human-like" use of hierarchical syntax to communicate...The Amazon in 2050: Implementing the law could save a million square kilometers of rainforest
...t shows that simply implementing existing laws and proposed protected areas would spare the Amazon one million square kilometers of deforestation (one fifth of the entire forest area), avoiding 17 billion tons of carbon emissions to the atmosphere, the elimination of several forest formations, and the degrada...Diverse tropical forests defy metabolic ecology models
...l these forests," remembers Muller-Landau. "If the proposed general rules truly applied, they would be tremendously useful - for example, they would help us predict how much above ground carbon is stored in tropical forests. There are some general similarities among sites in the tree size distributions, so it...Malaria parasites develop in lymph nodes
... all end up in the liver, Ménard said. "Nobody had proposed that they actually might stop" in the lymph nodes and develop there, he observed. By 52 hours after the mosquito bites, no parasites remained in the lymph nodes, which suggests that they can't develop completely there, Ménard said. Only fully devel...Invasive species harms native hardwoods by killing soil fungus
...d interactions among native organisms -- have been proposed to explain the success of invasive species, this new work is the first to show that an invasive plant harms native plants by thwarting the biological "friends" upon which they depend for growth. The work, which provides striking evidence for a unique...Parents need to be educated about HPV vaccinations for daughters
...tand the context in which HPV vaccination is being proposed and that they realise that it is not a treatment for the virus once it has been contracted, or for cervical cancer if the disease has started to develop. Vaccination should not be misconstrued as a green light for sexually permissive behaviour ?rath...Predators keep the world green, ecologists find
...port the so-called "green world hypothesis," first proposed in 1960 by United States scientists Nelson Hairston, Frederick Smith and Lawrence Slobodkin. Despite being almost 50 years old, the green world hypothesis has been almost impossible to test until now. "Since the landmark paper by Hairston et al, eco......icularly. Forty years ago, evolutionary biologists proposed that such periods of drought led to rainforest refuges in which many new species of birds, butterflies, and plants arose. Recent geological work, however, has failed to find much evidence of such forest refuges in the Amazon basin, and the Pleistoc...