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Tag: "propose" at biology news

Super predators and mass extinctions

...every 26 million years, leading some scientists to propose that they may be caused by rare collisions with comets or asteroids. A researcher in Poland thinks it may be possible that extraordinary predators are at fault instead. Adam Lipowski (Adam Mickiewicz University) constructed a numerical model of many...

Reservoirs may accelerate the spread of invasive aquatic species, researchers say

...at freshwater lakes, Havel, Lee, and Vander Zanden propose they could provide a haven that helps invaders from saline and brackish habitats adapt to fresh water. Several invasive species are suspected to have benefited from the use of reservoirs as avenues, including Daphnia lumholtzi, a water flea from the...

Stopping smallpox in its tracks: A new anti-viral approach

...einherz and colleagues from Harvard Medical School propose a new antiviral therapy ?a low molecular weight inhibitor of signaling mediated by the smallpox growth factor (SPGF). SPGF targets the erbB-1 signaling molecule, which normally initiates an intracellular cascade that facilitates viral replication. ...

Iron exporter revealed that may explain common human disorder

...for hemochromatosis, Andrews said. The researchers propose that, in patients with the disease, perturbations in iron homeostasis result from a failure to control iron export through ferroportin, leading to increased iron release from macrophages and enhanced intestinal absorption. Indeed, patients with the d...

Not-for-profit publishers call NIH public access rule a missed opportunity

...ure for more than 100 years," Hogan said. "What we propose would expand this partnership in a way that benefits the public, advances scientific research, and preserves this important relationship." "We believe the NIH rule will not achieve the goal of better access to science and will place an unreasonable ...

Scientists solve structure of key protein in innate immune response

...pocket near its amino terminus," says Dr. Lee. "We propose that this pocket is the main binding site for LPS because previous biochemical studies demonstrate that amino acid residues comprising the pocket are critical for LPS binding. Most, if not all, of the CD14 ligands compete with LPS for CD14 binding. T...

DNA Recombination and Repair—A New Twist to RecA Function

...olecules per helical turn in a RecA filament. They propose that the RecA molecules hydrolyzing ATP at any given moment are aligned in a “stripe?that runs along the side of the filament. This stripe of ATP hydrolysis moves around the fiber in a repeating pattern of six steps. At the 5' end of the fiber, ATP h...

Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers

..., researchers at UC Irvine and Humboldt University propose that insects such as grasshoppers, moths, butterfl...ects like grasshoppers discontinue breathing. "We propose that most insects stop breathing in order to lower their internal oxygen concentration to physiologi...

Novel Enzyme Shows Potential As An Anti-HIV Target

...-fold reduction in HIV transcription. The authors propose a cycle of transcriptional transactivation in which SIRT1 deacetylates Tat at the HIV promoter. Deacetylated Tat associates with CyclinT1 and TAR, and leads to transcription. Tat acetylation dissociates Tat from CyclinT1 and TAR, and transfers Tat to...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

... like? "As with currentsoftware collaborations, we propose a website where volunteers couldsearch and annotate shared databases. Individual pages would host taskssuch as searching for new targets, finding chemicals to attack knowntargets, and posting data from related chemistry and biologyexperiments. Volunt...

The secret to longevity in tubeworms

...and individual longevity, leading Cordes et al. to propose that L. luymesi also uses its roots to release sulfate back to the microbial consortia from which it draws its sulfide. Without this return of sulfate, the model predicts an average lifespan of only 39 years in a colony of 1,000 individuals; with it,...

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