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Tag: "propose" at biology news

New drug could reduce tissue damage after heart attack

...we were able to design the CRP inhibitor. "We now propose to develop a CRP inhibitor as rapidly as possible for testing in patients with heart attacks. "The drug would be given as soon as patients arrived in hospital. If effective, it would reduce the amount of damage in the heart, thus limiting both earl...

Scientists show how thinking can harm brain cells

... California at San Diego, the Rochester scientists propose a strategy of chemical preconditioning to induce adaptations in nerve cells that would enable the cells to better withstand toxic attacks, prevent injury, and preserve function. "Preconditioning would allow the nervous system to experience stress an...

Chlamydia parasite lives off our fat

...ggests an entirely novel pathogenic mechanism. "We propose that Chlamydia use lipid droplets in a previously unknown pathway for lipid acquisition," says Kumar. "Alternatively, it is possible that the recruitment of lipid droplets constitutes an example of 'organelle mimicry' where Chlamydia escapes recognit...

Brain activity related to processing faces is similar in people with, without autism

...amygdala, the "anxiety center" of the brain. They propose that the use of behavioral interventions aimed, perhaps, at de-sensitizing autistic individuals to the anxiety triggered by looking at faces may help to improve the quality of social interactions, at least from the perspective of caregivers and other...

New view of cancer: 'Epigenetic' changes come before mutations

...ld have remained off. Feinberg and his colleagues propose that cancers develop via a three-step process. First, there is an epigenetic disruption of progenitor cells within an organ or tissue, altered by abnormal regulation of tumor-progenitor genes. This leads to a population of cells ready to cause new gr...

Plants reveal a secret and bring researchers nearer a cleaner future

...he "Kok cycle" with an additional intermediate and propose a new reaction mechanism on a molecular basis for the release of dioxygen. This gives new insight into the mechanism of photosynthesis. In order to study this process, the use of synchrotron light was crucial: "A very intense and stable X-ray beam ...

Brain networks change according to cognitive task

... task at hand." The Northwestern researchers also propose to explain the role of each brain region as it interacts within a complex network to achieve a specific cognitive goal. The conventional method for analyzing fMRI data, which can only show which brain regions are active in a given task, showed two b...

Study charts origins of fear

...ng NR2B in the pre-frontal cortex of the brain, we propose that fear memory originates from a network of receptors, rather than one simple area," Zhuo says. "It is more complex than previously thought." The next step, according to Zhuo, is to determine how NR2B directly affects memory formation and storage ...

Clearing jams in copy machinery

... toolbelt as needed. O'Donnell and his colleagues propose two explanations for how the polymerase switch is controlled. "One possibility is that the beta clamp may sense when Pol III stalls, triggering a change in beta that pulls the polymerase from the primed site, allowing Pol IV to take over synthesis,"...

Opiate cocktail may spare cells from morphine's dark side

...pendence. In light of their findings, the authors propose that an opiate cocktail that combines morphine with small doses of methadone would increase the effectiveness of morphine for the treatment of chronic pain. He, L., and Whistler, J.L. (2005). An Opiate Cocktail that Reduces Morphine Tolerance and De...

Simple explanation for complex pattern of feather development

...ome of the secrets of branched feather growth, and propose how the unique complexity of feathers may have evolved. Ornithologist Prum led a team including anatomists Matthew Harris and John Fallon at the University of Wisconsin, statistician Scott Williamson at Cornell and Hans Meinhardt at the Max Plank Ins...

UCR biochemist goes to Washington with high-protein corn

Daniel Gallie's findings propose a useful approach to feed the world's growing population Corn with twice its usual content of protein and oil and about half of its usual carbohydrate content is what Daniel Gallie, professor of biochemistry at UC Riverside, will present at a congre...

Change in gene may be underlying molecular defect in some colorectal cancers

...opment in the U.S. population, it is reasonable to propose testing to determine whether healthy persons with MGMT promoter methylation in normal colorectal mucosa are at higher risk of developing a colon tumor than those without such methylation." In an editorial, Edward Giovannucci, M.D., Sc.D., of the Har...

Hormones and growth: The control of body size and developmental growth rate in fruit flies

...ation. On the basis of their findings, the authors propose that under normal conditions, growth of prothoracic gland during development helps larval flies determine when a critical body weight has been reached and when metamorphosis should be initiated. ...

Researchers predict infinite genomes

...view of microbial genomes, Tettelin and colleagues propose describing a species by its "pan-genome": the sum of a core genome, containing genes present in all strains, and a dispensable genome, with genes absent from one or more strains and genes unique to each strain. The pan-genome is more than mere synt...

Mechanism regulating tooth shape formulation found

...panese colleagues from the University of Kioto now propose a 'balance of induction' mechanism directing the placement of tooth shape features called cusps. Position and shape of cusps determine whether a tooth shape belongs to human or mouse, for example. Whereas developmental initiation of cusp formation is...

Discovering an ecosystem beneath a collapsed Antarctic ice shelf

... from the planet's crust. Domack and his coauthors propose that methane from deep underwater vents likely provide the energy source capable of sustaining the chemical life at the observed 850-meter [approximately 2800-foot] depth. Such extreme cold-vent regions have previously been found near Monterey, Cali...

Depression gene may weaken mood-regulating circuit

...ircuitry during early development, the researchers propose that the short variant leads to stunted coupling in the circuit, a poorly regulated amygdala response and impaired emotional reactivity ?resulting in increased vulnerability to persistent bad moods and eventually depression as life's stresses take th...

Mouse with designer liver has enhanced glucose tolerance, insulin response

...signals flowing through IRS and Akt proteins. "We propose that Gab1 acts as a negative regulator on insulin signal strength in the liver," said Dr. Feng. "In this work, by making a new liver-specific gene knockout mouse model, we found a novel balancing mechanism for control of liver insulin signaling. Our ...

Python a 'hearty' eater

...y role in pumping blood. Hicks and his colleagues propose that these animals could be an informative model for investigating fundamental mechanisms leading to cardiac remodeling and ventricular growth in other animals, including humans. Hicks' research is supported by the Integrative Organismal Biology pro...

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