proper 2 1

Tag: "proper" at biology news

Neuronal 'traffic jam' marks early Alzheimer's disease

..." within neurons that causes swelling and prevents proper transport of proteins and structures in the cells, according to new studies by Howard Hughes Medical Institute researchers. In mouse models of Alzheimer's disease and in human brain samples from people with the disease, researchers observed a charac...

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...undreds of proteinsrequire iron to carry out their proper function, so without thisnutrient, there is a complete reorganization of how cellular processesoccur."The cellular player responsible for the metabolic reprogramming is aprotein called Cth2. Thiele's team found that iron-deprived cellsoverproduce Cth...

Learning to fight an adversary that won't stay down

...that we can put the role of these organisms in the proper evolutionary perspective. This subject, and antibiotic resistance in particular, has fascinated Davies since he began postdoctoral work on antibiotics and resistance mechanisms at Harvard Medical School in the early 1960s. "The microbes are evolving...

An HIV Protein Plays a Surprising Role in Gene Activation

...can enhance transcriptional activity by supporting proper elongation of nascent transcripts. Tat, an activator encoded in the HIV genome, is required for HIV gene activation and viral replication. It affects these processes, the current model holds, by stimulating transcript elongation and increasing RNA p...

White blood cell waste disposal system plays critical regulatory role

...Although the specific mechanisms that regulate the proper ratios of neutrophil production and destruction are not well understood, it is known that the immune signaling molecules IL-17 and G-CSF stimulate neutrophil production. In addition, a newly discovered molecule called IL-23 that is produced by phagoc...

New RNA polymerase discovered in plants

... one of the four chemical subunits of DNA. Without proper DNA methylation, higher organisms from plants to humans have a host of developmental problems, from dwarfing in plants to tumor development in humans to certain death in mice. Pikaard thinks that Pol IV helps make siRNAs that then direct DNA methyla...

NJIT Presidential Award winner takes stem cell research another step

...ir magic: Under the right conditions, or given the proper signals, they have the ability to turn into different cell types. Arinzeh is doing exactly that: developing signals, in the form of biomaterials, that will help adult stem cells turn into cells that, if injected into a diseased area of the human bod...

Increased risk of osteoporosis associated with gene that one in five people have

...eaks down estrogen as a normal part of maintaining proper estrogen balance. Within the general population, several variations of the CYP1A1 gene exist, and the variants differ from one another by one or more DNA base pairs. "Previous studies showed that some CYP1A1 variants are linked to estrogen-related c...

WHO Warns Of Increased Risk Of Vector-borne Diseases In Tsunami-affected Areas

...or control strategies including establishment of a proper drainage system and engineering methods are key co...d populations live in temporary conditions without proper shelter. Different mosquitoes cause different vector-borne diseases. Dengue fever is carried by the...

Buying Time Through Hibernation on Demand

...se the bacterial or viral cause and administer the proper antibiotic. "Here's a patient group, quite commonly found in emergency rooms around the country, who would do well if they could just have their core body temperature taken down in order to buy them time until the pathology reports come back and the...

U-M team recovers ancient whale in Egyptian desert

...se the bacterial or viral cause and administer the proper antibiotic. "Here's a patient group, quite commonly found in emergency rooms around the country, who would do well if they could just have their core body temperature taken down in order to buy them time until the pathology reports come back and the...

Brain-mapping technique aids understanding of sleep, wakefulness

..." to tip from one side to the other and maintain a proper balance between time spent awake and time spent asleep is still a big mystery in brain science. By shedding light on the network of neural connections involved in sleep, he said, his and other studies will help unravel the mechanisms involved in slee...

White Blood Cell 'Waste Disposal' System Plays Critical Regulatory Role

...Although the specific mechanisms that regulate the proper ratios of neutrophil production and destruction are not well understood, it is known that the immune signaling molecules IL-17 and G-CSF stimulate neutrophil production. In addition, a newly discovered molecule called IL-23 that is produced by phagoc...

Nano-bumps could help repair clogged blood vessels

...of more new bone tissue, which is critical for the proper attachment of artificial joints once they are implanted. Now the biomedical engineers have seen the same kind of increased attachment for endothelial and vascular smooth muscle cells lining the insides of arteries, said Thomas Webster, an associate ...

Medical whistleblowers speak out

...er, is that "the race to approve new drugs without proper safety testing may be compromising the public's health." A research scientist from a major pharmaceutical company, who participated in the roundtable by speakerphone to protect anonymity, said that "drug companies will not conduct safety studies unle...

New understanding of DNA repair may pave way to cancer treatments

...ircumstances in order to devise ways to regain the proper balance," he said. The Ronai lab's work on ATF2 was started at Mount Sinai School of Medicine in New York City, from which Dr Ronai and his colleagues recently relocated to the Burnham Institute. This study was carried out in collaboration with Wolf...

Scientists discover that three overlapping signals in embryo help get the backbone right

... don't know what they'll become until they get the proper signal. This concept is at the root of today's excitement over embryonic stem cells, which are basically naïve cells that, theoretically, can be stimulated to become any tissue of the body. In fact, the proteins normally used by the embryo have rece...

UCSD medical/bioengineering reseachers show titanium debris satobtage artificial joints

...roscopic studies revealed osteoblasts did not form proper adhesions, with small- and medium-sized titanium particles concentrated inside cells. Increased production of the protein RANKL by osteoblasts recruited and activated osteoclasts at the insertion sites, further weakening the bone. Larger titanium par...

15-year hunt finds cause of pseudothalidomide syndrome

... the cells tend to stop growing or die, precluding proper development of the limbs, palate and other structures. The researchers were funded by the Japanese Ministry of Education, Culture, Sports, Science and Technology; the Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnologia; the Smile T...

Remote control flies? Fly behavior controlled by laser light

...jump-starting the nerve cell's activity before the proper moment, Lima and Miesenböck caged the ATP with other chemical compounds that could be removed by the laser light. Miesenböck says one of the most difficult parts of the experiment was deciding which particular nerve cells to target with the remote c...

1 2 3 4 5 6 7