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Tag: "proof" at biology news

Neurons grown from embryonic stem cells restore function in paralyzed rats

...cessful demonstration of functional restoration is proof of the principle and an important step forward. We must remember, however, that we still have a great distance to go," says Elias A. Zerhouni, Director of the National Institutes of Health. "This study provides a 'recipe' for using stem cells to rec...

Ammonia-loving archaea win landslide majority

...on of the genomes from soil organisms, thus giving proof that crenarchaeota are in fact active and not just dormant residents in the soil. Crenarchaeotal gene counts also do not change with soil depth, while bacterial gene counts drop significantly as one goes deeper. "It might mean that they can ...

HIV infection requires an accomplice: B cells with special protein direct HIV to T cells

...eterrent against T cell infection as well, further proof that to invade T cells, HIV requires DC-SIGN to be expressed on B cells. ...

Bird brains shrink from exposure to contaminants

...says new University of Alberta research--the first proof that natural exposure to a contaminant damages the brain of a wild animal. "These residues have been persisting since the late 1960s--that's what is really disturbing," said Dr. Andrew Iwaniuk, a post-doctoral research fellow in the U of A's Depar...

Diabetes hits 275 Australians each day as pandemic spreads

...obesity occurring each day, we now have compelling proof that Australia's diabetes epidemic is in full flight." Professor Zimmet said. In addition to measuring the development of new cases, the follow-up study showed that during the last 5 years: People's waistlines increased on average by 2.1 cm and th...

Protein's role in regulating cell death sets direction for cancer research

... University study has found. "This work provides proof in principle that pharmacological inhibition of calpain may be used to block cell death in situations where this is not desirable, such as in neuronal cells of Alzheimer's or Parkinson's patients, but to promote cell death in cancer cells where this ...

Researchers discover new gene responsible for brittle bone disease

...he findings of the current study provide the first proof that osteogenesis imperfecta can be inherited in a recessive manner. Previously, the genes known to be involved in OI were dominant, meaning that if you had a defect in the gene in your chromosome, you developed the disease. That left open the possib...

Boston University biomedical engineers win major grant for pursuit of the '$1,000 Genome'

...pproach to DNA sequencing. "We are very close to a proof of principle that we can read a small number of these bases, perhaps six or eight, using this method," said Meller. "From there, it is a small step to reading tens, and later hundreds, at a time. That would produce an orders-of-magnitude reduction in...

An artificial cornea is in sight, thanks to biomimetic hydrogels

...rs ago, in a pilot study for a Bio-X grant to show proof of concept, Ta began to test the hydrogel in assays to make sure it was not toxic to cells. Soon other experts joined the effort. Jaan Noolandi in Ophthalmology managed projects, worked with potential sponsors and provided insight into polymer physic...

'Erectile dysfunction' drugs heighten natural anti-cancer activity

... to lack an immune system, tumors were unaffected, proof of principle, the scientists say, that the drug is abetting the immune system’s own cellular response to cancer. In a report published in the Nov. 27 issue of the Journal of Experimental Medicine, the Hopkins team says boosted levels of the chemic...

Natural protein stops deadly human brain cancer in mice

...the public within three to four years. "This was proof of the idea that BMPs could stop glioblastoma by depleting the stem-cell-like population that feeds it," says Henry Brem, M.D., chairman of the Department of Neurosurgery at Hopkins and a collaborator in the study. "This opens exciting doors to futur...

Learning during sleep?

...ted. Their new study offers the hitherto strongest proof that new information is transferred between the hippocampus, the short term memory area, and the cerebral cortex during sleep. According to their findings and contrary to previous assumptions, the cerebral cortex actively controls this transfer. The ...

Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration

...tment of blinding diseases," he says. "We now have proof of principle that our approach to repairing damaged retina by transplantation of appropriate cells can be successful." Swaroop sees several next steps in his quest to find treatments for retinal and macular degeneration. His research team will co...

Light wine intake is associated with longer life expectancy in men

...uit smoking, if you smoke. There is no scientific proof that drinking wine or any other alcoholic beverage can replace these conventional measures....

Faster, low cost sequencing technologies needed to drive era of personalized medicine

...ding to Zhang. The researchers' first goal is a proof of principal for their approach. They plan to synthesize a universal DNA nanoarray on a 100 micrometer by 100 micrometer chip, about the size of a dust mite, by 2009. The award to Zhang and his team was one of nine grants given by the NIH to achi...

'Exercise pill' switches on gene that tells cells to burn fat

...rmanent, turned on before birth. While a dramatic proof of concept that metabolic engineering is a potentially viable approach, it offers no help to an adult whose muscles are already formed and who now would benefit greatly from having more active, fat-burning muscles. That is why the potential of c...

Satellites shed light on global warming

...r altimeter that oceanographers were able to offer proof of their existence by mapping the sea surface height and seeing them move by following the measurements of the surface. Radar altimeters work by sending thousands of separate radar pulses down to Earth per second then recording how long their ech...

No sex for 40 million years? No problem

...e have been around for millions of years. "Our proof that natural selection has driven their divergence into distinct species is another example of these miniscule creatures surprising scientists ?and their ability to survive and adapt to change certainly raises interesting questions about our understa...

Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer

...s first-in-human study and we've seen an exciting proof of concept with no significant drug-related toxicity," says principal investigator Charles Lu, M.D., associate professor in M. D. Anderson's Department of Thoracic, Head and Neck Medical Oncology. Blinded analysis of pretreatment and post-treatm...

Application of Genomatix in silico methods reveals novel cancer associated genes

...ghted that an ever increasing number of scientists proof the validity of our concepts and experience the value of our integrated approach. This excellent work, carried out by researchers at The Conway Institute of the University College, Dublin, The Mater Misericordiae University Hospital in Dublin and The...

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