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Tag: "prone" at biology news

U-M scientist to talk about tissue engineering at AAAS

...ich bone quality declines leaving them fragile and prone to breaking. Parathyroid hormone stimulates bone growth in these patients, and Krebsbach sees potential to use it for similar gains in tissue engineering new bone. Bone morphogenetic proteins help cells differentiate into specific kinds of bone, and...

Pulsating ultrasound enhances gene therapy for tumors

...gaps between the cells, making it leakier and more prone to taking up various genes, agents and compounds," said Victor Frenkel, Ph.D., a staff scientist for the diagnostic radiology department at the NIH Clinical Center in Bethesda, Md. Working with lead authors Kristin M. Dittmar, M.D., and Jianwu Xie, ...

Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression

...rtain mRNAs is making them inherently unstable and prone to degradation. This inherent instability is built into the 3' tail of the mRNA in the form of noncoding stretches of RNA called AU-rich elements. Lots of genes, including inflammatory cytokines and cancer-causing oncogenes, have these AU-rich eleme...

Insight into DNA's 'weakest links' may yield clues to cancer biology

...ding humans, contain regions that are particularly prone to breaking under conditions of stress and in canc... tend to duplicate late and also include sequences prone to forming kinks, or hairpin structures, like those observed in yeast. "The findings may ultimately...

Findings have implications for tracking disease, drugs at the molecular level

...out' quickly under continuous observation, and are prone to blinking on and off. "The gold particles, however, do not blink or burn out, even after hours of observation, and the brightest ones emit much more light than do molecules," he said. "We now have the ability to see single nanoparticles under cond...

To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists

...engineer jealous. Nevertheless, all organisms are prone to some level of damage because no replication machinery is perfect, and with large genomes of billions of bases of DNA to be copied many billions of times over the lifetime of an organism, a certain level of spontaneous mutations will occur -- mista...

Brain Scan Study of Smokers Reveals Signature of Craving

...ulty quitting smoking and may also be particularly prone to relapse, McClernon said. While experts advise that all people attempting to quit avoid situations or objects that remind them of smoking, the new results suggest that such measures may be particularly important for some smokers, he said. The Duke...

Excess liver gene protects against high-fat diet

...o lacked a second gene that made them particularly prone to cardiovascular disease. When fed normal mouse chow, mice with a greater than average number of the receptors exhibited a rise in blood cholesterol and triglyceride levels. In contrast, altered mice fed a high-fat, Western diet showed improvements...

Scientists inhibit cancer gene

...studies had demonstrated that these mice were very prone to tumors. For the new study, the Hunstman Cancer Institute team deleted the DGK iota gene in these mice and found that they developed few tumors, while mice with an intact DGK iota gene and an activated Ras gene exhibited significantly more tumors. ...

Major advance made on DNA structure

...repair, and why some DNA structures are inherently prone to damage and mutation. Understanding DNA structure, the scientists say, is just as necessary as knowing gene sequence. The human genome project, with its detailed explanation of the genetic sequence of the entire human genome, is one side of the coi...

Gambling monkeys give insight into neural machinery of risk

... the neurotransmitter serotonin might be more risk prone and impulsive," said Platt. "Disturbances in such neurotransmitter systems might be the basis of pathological conditions like pathological gambling, obsessive-compulsive disorder and depression. We can do pharmacological manipulation of the serotonin...

New Lab Research May Help Those Deafened By Immune System Attack

... lupus or rheumatoid arthritis. Such people may be prone to losing all or part of their hearing due to an overzealous autoimmune reaction. All eight study participants who had systemic autoimmune diseases showed signs of antibodies against IESCA. Six of them regained hearing after steroid treatment. U-M r...

Rodent social behavior encoded in junk DNA

...nk, the repetitive DNA sequences, which are highly prone to mutate rapidly, may ultimately exert their influence through complex interactions with other genes to produce individual differences and social diversity, according to Young. ...

Solution to 'legionella'

...rs of factory buildings and installations that are prone to be the focus for the proliferation of Legionnaires' disease. In order to validate the system, the team of INASMET-Tecnalia experts designed a refrigeration tower simulation within a biologically-isolated laboratory (P2 level). A wide range of tri...

Enzyme affects hypertension by controlling salt levels in body

...lation groups, such as African-Americans, are more prone to develop salt-sensitive high blood pressure, suggesting that genetic factors may play a role in the disease. One extension of the current work may lead to a better understanding of hypertension that is induced by low potassium intake. Previous stu...

New clues to the dark side of a key anti-tumor guardian

...mon molecular mechanism. Because neurons are less prone to tumor formation than other cell types, and because disruption of p53 activity in neurons was sufficient to extend lifespan in the fruit fly, the new findings suggest that by attending to p53 activity in different cell types, it may be possible to ...

Genetic testing still smart choice, despite uncertainties

...niversity. The testing can work miracles for women prone to miscarriages or who carry genetic diseases, he said. "If you are at risk for genetic diseases, it changes your outlook on starting a family," he said. "PGD allows them to get pregnant. It's a dramatic improvement when it works." More than 45,00...

Researchers show how air pollution can cause heart disease

...colleagues divided 28 mice, which were genetically prone to developing cardiovascular disease, into two gro...gh-fat diets. Mice exposed to PM2.5 also appeared prone to developing high blood pressure, another element of cardiovascular disease, because their arteries...

Gene increases risk of tuberculosis

...enetic differences that make some individuals more prone to developing disease than others. Indeed, a recent scientific study found that a particular region on the human chromosome 17 was associated with increased risk of developing active tuberculosis, but the exact gene(s) responsible for this effect wa...

Antibacterial coatings cut infection rates

... A significant number of hip and knee implants are prone to infection after surgery and in many cases are not amenable to treatment with antibiotics, according to Hans Griesser, Professor of Surface Science and Deputy Director of UniSA's Ian Wark Research Institute. "For patients in this situation it may ...

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