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Tag: "prompts" at biology news

Genetically modified natural killer immune cells attack, kill leukemia cells

...y modified to brandish a powerful "on-switch" that prompts them to aggressively attack and kill leukemic cells. This finding, from researchers at St. Jude Children's Research Hospital, suggests a way to improve the outcome of children who receive treatment for acute lymphoblastic leukemia (ALL) or other bloo...

Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells

...y modified to brandish a powerful "on-switch" that prompts them to aggressively attack and kill leukemic cells. This finding, from researchers at St. Jude Children's Research Hospital, suggests a way to improve the outcome of children who receive treatment for acute lymphoblastic leukemia (ALL) or other bloo...

Leprosy microbes lead scientists to immune discovery

...ave discovered how the body's early warning system prompts a rapid immune response by two separate armies of defensive cells. The finding helps explain why, when threatened by microbes like the leprosy bug, this initial defense sometimes succeeds in limiting the damage, but in other cases yields to a dangero...

Researchers test new therapy for advanced melanoma

...h Florida are testing a promising new therapy that prompts the immune system to aid in the fight against melanoma tumors. "This is a milestone clinical trial because it is the first time that electroporation is being used to deliver plasmid DNA in a gene therapy study in humans," said Richard Heller, PhD, U...

Environmental chemical cocktail may sabotage sperm

...er external compounds have acted on the cell, that prompts an appropriate response. In the case of sperm, increased cAMP production appeared to stimulate premature sperm capacitation. "The sperm were still alive and their ability to move was unaffected, but the spontaneous acrosome reaction meant that they w...

Thinking the pain away? Study shows the brain's painkillers may cause 'placebo effect'

Sham painkiller prompts brain to release endorphins, bringing real relief to those in pain Just thinking that a medicine will relieve pain is enough to prompt the brain to release its own natural painkillers, and soothe painful sensations, a new University of Michigan stud...

Elderly mice yield clues to the process of growing old

...ve found that an accumulation of genetic mutations prompts a cascade of programmed cell death that seems to u...mitochondria slow metabolism. In turn, that change prompts cells to produce fewer of the reactive free radical molecules. The symptoms of aging become pronoun...

Why do aneurysms form? New studies suggest leading role for white blood cells

... question of how those enzymes get there, and what prompts them to arrive, has been unanswered. "Neutrophils are known to carry some of these enzymes, called matrix metalloproteinases and chemokines, which help them attack invaders," says Upchurch. "We wanted to see what the role of neutrophils was in the e...

'Virus chip' detects new virus in prostate tumors

...ntification of this virus in human prostate tissue prompts many more questions than it answers, they emphasize. "A hit on the array is not the end of the project; it's the beginning," Ganem says. "Pathogen discovery is really hard work." The team intends to carry out epidemiology studies to determine how wi...

Wisconsin scientists discover a master key to microbes' pathogenic lifestyles

...erica and Africa. In most instances, the infection prompts only mild symptoms. Untreated, however, it can be fatal. What's more, the microbe can lay dormant in an infected host for years. "All of these organisms exhibit this property of latency," says Klein. "They can remain dormant until immune defenses ar...

Great (taste) expectations: Study shows brain anticipates taste, shifts gears

...fect. How the brain processes this faked input and prompts the body to respond is largely a mystery of neuroscience. Now, however, scientists have begun to peel back some of the neurological secrets of this remarkable phenomenon and show how the brain can be rewired in anticipation of sensory input to respo...

Honeybee decision-making ability rivals any department committee

... the waggle dance, the researchers found, and that prompts other scouts to visit a recommended site. If they agree it's a good choice, they also dance to advertise the site and revisit it frequently. Scouts committed to different sites compete to attract uncommitted scouts to their sites, the researchers hav...

Molecule does more than slice and dice RNA

... causes genes to be turned off and which, in turn, prompts a host of key developmental events. With the structure of Dicer solved, Doudna's group showed that the enzyme is more than a molecular cleaver -- it also carefully measures and snips strands of RNA into precise increments. When Dicer cleaves large s...

Advanced genomics and proteomics improve the diagnosis and treatment of a deadly lung disease

... causes genes to be turned off and which, in turn, prompts a host of key developmental events. With the structure of Dicer solved, Doudna's group showed that the enzyme is more than a molecular cleaver -- it also carefully measures and snips strands of RNA into precise increments. When Dicer cleaves large s...

Losing sleep undoes the rejuvenating effects new learning has on the brain

...e task, the researchers noted. Sleep restriction prompts use of a secondary strategy On the other hand, the sleep-restricted rats that were required to locate the platform using visual and odor cues did better on the task than their rested counterparts. This was an unexpected finding. Hairston et al. be...

Gene first linked to rare disease may trigger skin cancer, other tumors

... normal skin cells, chemical treatment or UV light prompts the transport of CYLD out into the cytoplasm, they reported. Once there, the protein binds and modifies the cancer promoter Bcl-3 to prevent its nuclear accumulation. In addition to elucidating the cause of cylindromas, the findings might have impor...

Researchers use multiphoton microscopy to watch chromosomes in action

... a cell's nucleus when an external stimulus (heat) prompts specific genes to activate, and how those activated genes direct the production of proteins, which protect the fly against the stress of heating. "Whenever a cell is stressed -- bingo, it will produce proteins that will help the cell resist stress,"...

Research links 'ecstasy' to survival of key movement-related cells in brain

...egally as "ecstasy," is a synthetic stimulant that prompts the secretion of large amounts of the neurotransmitters serotonin, dopamine and norepinephrine in the brain. This secretion can lead to prolonged periods of activity, hallucinations and euphoria. Before the United States banned it in 1985, MDMA was t...

Newly discovered behavior in cancer cells signals dangerous metastasis

... or "co-factor" in or around epithelial cells that prompts it to activate, the researchers said. They speculate that this co-factor could be activated by contact with stroma --the supporting structural cells of a tumor -- because the stroma is where the majority of epithelial-type cancer cells were observed....

A key antibody, IgG, links cells' capture and disposal of germs

...most invading microbes. Specifically, the antibody prompts phagosomes and lysosomes to dock and bind to each other with actin filaments, the first step in the unification of the two vesicles. Among the antibody's other known roles, Nohturfft's group has now shown that IgG serves to accelerate the creation...

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(Date:4/17/2014)... in PLOS Pathogens , children who live in ... mount an immune response to infection with malaria parasites ... high fever and illness and partially control the growth ... help researchers develop future interventions that prevent or mitigate ... year, approximately 200 million cases of malaria occur worldwide, ...
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