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Tag: "promoters" at biology news

Bacteria collection sheds light on urinary tract infections

...ring subtherapeutic doses of antibiotics as growth promoters in animals. E.coli is common bacteria found in humans and animals. Thousands of E.coli live in the organs of humans and animals and provide multiple benefits such as aiding in digestion of certain nutrients. However, E.coli is also commonly associat...

Genetic therapy reverses nervous system damage in animal model of inherited human disease

...imit the number of injections by the use of strong promoters that could increase the amount of enzyme that comes from corrected cells." Although encouraged by their findings, the researchers note that any clinical trials in humans might be years in the future. ### Video comparing a cat with AMD to one that ...

Whole genome promoter mapping - Human Genome Project v2.0?

...rn gene expression on or off. If we know where the promoters are, we can study how the genetic switches work in...ther. The identification of such a large number of promoters means that we can begin to answer these sorts of questions." ...

Master regulatory gene found that guides fate of blood-producing stem cells

...n factor, called NF-Y, was required for activating promoters of all of these genes. What's more, they found that fully assembled NF-Y was activated in stem cells and disappeared when the stem cells became mature cell types, through the induction and loss of one its subunits, NF-Ya. "When we overexpressed NF-Y...

'Perception' gene tracked humanity's evolution, scientists say

...hin promoter was unique to humans. Other primates' promoters were far more homogeneous. Exactly how prodynorphin influences human perception is unknown. Evidence for its various effects comes entirely from clinical studies of people who have mutations in the gene. Past clinical studies have also indicated a ...

Basic work on E. coli identifies two new keys to regulation of bacterial gene expression

...tigated the interaction between RNA polymerase and promoters from the E. coli chromosome. RNA polymerase reads ...p found that there is a specific region within DNA promoters that makes contact with a highly conserved but previously underappreciated segment of the sigma subu...

Learning the language of DNA

...standing the language of cells lies in identifying promoters - the DNA regions at the start of genes that regul...ate their activity. "We have identified the core promoters of the large majority of genes in the mouse and human genomes, expanding the number of known promote...

Scientists map key landmarks in human genome

... used the technique to locate nucleosomes in 3,692 promoters (regions of DNA that interact with regulatory fact...free regions, respectively. Analysis revealed that promoters of genes that had similar expression status (they were all "off" or "on") had related nucleosome loc...

Beyond the DNA: Chemical signatures reveal genetic switches in the genome

...ures of modified histones that correspond to known promoters and enhancers. These findings enabled us to genera...nable scientists to quickly identify enhancers and promoters for a gene, which will lead in turn to rapid identification of factors that control its expression."...

Effect on breast tumors of DNA alternations in 3 genes described

...ecific genes that are most likely to become cancer promoters when exposed to a process called DNA promoter hypermethylation. Hypermethylation is a process that causes genes that promote normal cell growth to produce proteins that cause malignant behavior, or unregulated cell growth. Until now, data has been v...

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